P
Peter M. Rothwell
Researcher at University of Oxford
Publications - 815
Citations - 77220
Peter M. Rothwell is an academic researcher from University of Oxford. The author has contributed to research in topics: Stroke & Population. The author has an hindex of 134, co-authored 779 publications receiving 67382 citations. Previous affiliations of Peter M. Rothwell include Leicester Royal Infirmary & University of Edinburgh.
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Journal ArticleDOI
Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke
Ken B. Hanscombe,Matthew Traylor,Pirro G. Hysi,Stephen Bevan,M. Dichgans,Peter M. Rothwell,Bradford B. Worrall,Sudha Seshadri,Cathie Sudlow,Frances M K Williams,Hugh S. Markus,Cathryn M. Lewis +11 more
TL;DR: One coagulation factor, factor XIII subunit B (FXIIIB), showed consistent effects in the concordance analysis, the estimation of polygenic risk, and the validation with genotype data, with associations specific to the cardioembolic stroke subtype.
Journal ArticleDOI
Non-cardioembolic stroke/transient ischaemic attack in Asians and non-Asians: A post-hoc analysis of the PERFORM study.
Takao Hoshino,Takao Hoshino,Leila Sissani,Leila Sissani,Julien Labreuche,Julien Labreuche,Marie-Germaine Bousser,Ángel Chamorro,Marc Fisher,Ian Ford,Kim Fox,Michael G. Hennerici,Heinrich Mattle,Peter M. Rothwell,Philippe Gabriel Steg,Philippe Gabriel Steg,Eric Vicaut,Pierre Amarenco,Pierre Amarenco +18 more
TL;DR: Compared with non-Asian patients, Asian patients had significantly higher risk of haemorrhagic events when given antiplatelet monotherapy for secondary prevention after non-cardioembolic stroke/transient ischaemic attack.
Posted ContentDOI
Automated lesion segmentation with BIANCA: impact of population-level features, classification algorithm and locally adaptive thresholding
Vaanathi Sundaresan,Giovanna Zamboni,Campbell Le Heron,Peter M. Rothwell,Masud Husain,Marco Battaglini,Nicola De Stefano,Mark Jenkinson,Ludovica Griffanti +8 more
TL;DR: This work improves BIANCA, the FSL tool for WMH segmentation, and proposes LOCally Adaptive Threshold Estimation (LOCATE), a supervised method for determining optimal local thresholds to apply to the estimated lesion probability map.
Journal ArticleDOI
The Intracranial-B2LEED3S Score and the Risk of Intracranial Hemorrhage in Ischemic Stroke Patients Under Antiplatelet Treatment
Pierre Amarenco,Leila Sissani,Julien Labreuche,Eric Vicaut,Marie-Germaine Bousser,Ángel Chamorro,Marc Fisher,Ian Ford,Kim M. Fox,Michael G. Hennerici,Heinrich Mattle,Peter M. Rothwell,Philippe Gabriel Steg,Hans-Christoph Diener,Ralph L. Sacco,Jacoba P. Greving,Ale Algra +16 more
TL;DR: The Intracranial-B2LEED3S score helps identify patients who are at a high risk of bleeding, however, other variables need to be identified to improve the score (e.g., microbleeds).
Journal ArticleDOI
Current Status of Carotid Endarterectomy and Stenting for Symptomatic Carotid Stenosis
TL;DR: The key issue that remains to be determined reliably is how the procedural risks of stenting vary with patient characteristics, and not whether endarterectomy is better than stenting or vice versa, but for whom is one technique likely to be better than the other.