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Peter W. Reeh

Researcher at University of Erlangen-Nuremberg

Publications -  187
Citations -  13190

Peter W. Reeh is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Calcitonin gene-related peptide & TRPV1. The author has an hindex of 61, co-authored 180 publications receiving 12118 citations. Previous affiliations of Peter W. Reeh include Heidelberg University & University of Pécs.

Papers
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Journal ArticleDOI

Local NGF and GDNF levels modulate morphology and function of porcine DRG neurites, In Vitro.

TL;DR: The experiments demonstrate that the compartmented culture chamber can be a suitable model to assess neurite properties from trophic factor specific primary sensory neurons and insights into mechanisms of gain or loss of function of specific nociceptive neurites may be achieved.

The roles of TRPV1, TRPA1 and TRPM8 channels in chemical and thermal sensitivity of the mouse oral mucosa

TL;DR: In this paper, the authors found that the lipophilic capsaicin, mustard oil and menthol effectively get access to the nerve endings below the multilayered squamous epithelium, while cigarette smoke and its gaseous phase were weakly effective releasing CGRP.
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A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Phase I Study of Analgesic/Antihyperalgesic Properties of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Healthy Female Subjects.

TL;DR: AS8477 was well tolerated in this study and showed significant effects on down-scoring the VAS pain score and a significant difference in LEP for ASP8477 100 mg over placebo but did in subjects who demonstrated positive capsaicin skin effects.
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Prostaglandin E2 and I2 facilitate noxious heat-induced spike discharge but not iCGRP release from rat cutaneous nociceptors

TL;DR: PGE (2) plus PGI(2) can sensitize the afferent function of nociceptors in the rat skin, by increasing heat- induced spike discharge, but not the heat-induced efferent response i.e. iCGRP release.