P
Philip Arevalo
Researcher at University of Chicago
Publications - 30
Citations - 816
Philip Arevalo is an academic researcher from University of Chicago. The author has contributed to research in topics: Population & Ecotype. The author has an hindex of 10, co-authored 27 publications receiving 458 citations. Previous affiliations of Philip Arevalo include Massachusetts Institute of Technology.
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Journal ArticleDOI
A major lineage of non-tailed dsDNA viruses as unrecognized killers of marine bacteria
Kathryn M. Kauffman,Fatima A. Hussain,Joy Y. Yang,Philip Arevalo,Julia M. Brown,William K. Chang,David VanInsberghe,Joseph Elsherbini,Radhey S. Sharma,Michael B Cutler,Libusha Kelly,Martin F. Polz +11 more
TL;DR: Data suggest that viruses of the non-tailed dsDNA DJR lineage are important but often overlooked predators of bacteria and archaea that impose fundamentally different predation and gene transfer regimes on microbial systems than on tailed viruses, which form the basis of all environmental models of bacteria–virus interactions.
Journal ArticleDOI
Adaptive radiation by waves of gene transfer leads to fine-scale resource partitioning in marine microbes.
Jan-Hendrik Hehemann,Philip Arevalo,Manoshi S. Datta,Xiaoqian Yu,Christopher H. Corzett,Andreas Henschel,Sarah P. Preheim,Sonia Timberlake,Eric J. Alm,Eric J. Alm,Martin F. Polz +10 more
TL;DR: In this paper, the authors describe a recent adaptive radiation leading to fine-scale ecophysiological differentiation in the degradation of an algal glycan in a clade of closely related marine bacteria.
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A Reverse Ecology Approach Based on a Biological Definition of Microbial Populations
TL;DR: A metric of recent gene flow is introduced, which when applied to co-existing microbes, identifies congruent genetic and ecological units separated by strong gene flow discontinuities from their next of kin, to facilitate the analysis of bacterial and archaeal genomes using ecological and evolutionary theory developed for plants and animals.
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Rapid evolutionary turnover of mobile genetic elements drives bacterial resistance to phages
Fatima A. Hussain,Javier Dubert,Javier Dubert,Joseph Elsherbini,Mikayla Murphy,David VanInsberghe,Philip Arevalo,Kathryn M. Kauffman,Bruno Kotska Rodiño-Janeiro,Bruno Kotska Rodiño-Janeiro,Hannah Gavin,Annika Gomez,Anna Lopatina,Frédérique Le Roux,Frédérique Le Roux,Martin F. Polz,Martin F. Polz +16 more
TL;DR: This article found that susceptibility to viral killing in marine Vibrio is mediated by large and highly diverse mobile genetic elements, which display exceedingly fast evolutionary turnover, resulting in differential phage susceptibility among clonal bacterial strains while phage receptors remain invariant.
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Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans
Haley L. Dugan,Jenna J. Guthmiller,Philip Arevalo,Min Huang,Yao-Qing Chen,Karlynn E. Neu,Carole Henry,Nai-Ying Zheng,Linda Yu-Ling Lan,Micah E. Tepora,Olivia Stovicek,Dalia J. Bitar,Anna-Karin E. Palm,Christopher T. Stamper,Siriruk Changrob,Henry A. Utset,Lynda Coughlan,Florian Krammer,Sarah Cobey,Patrick C. Wilson +19 more
TL;DR: The findings demonstrate that existing influenza-specific memory and route of exposure influence influenza immunity, and reveal that both preexisting immunity and exposure type shape protective antibody responses to conserved influenza virus epitopes in humans.