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Phillip D. Markham
Researcher at Litton Industries
Publications - 96
Citations - 11962
Phillip D. Markham is an academic researcher from Litton Industries. The author has contributed to research in topics: Virus & Simian immunodeficiency virus. The author has an hindex of 50, co-authored 95 publications receiving 11825 citations.
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Journal ArticleDOI
Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS
Robert C. Gallo,Syed Zaki Salahuddin,Mikulas Popovic,Gene M. Shearer,Mark H. Kaplan,Barton F. Haynes,Thomas J. Palker,Robert R. Redfield,James M. Oleske,Bijan Safai,Gilbert C. White,Paul Foster,Phillip D. Markham +12 more
TL;DR: Peripheral blood lymphocytes from patients with the acquired immunodeficiency syndrome (AIDS) or with signs or symptoms that frequently precede AIDS (pre-AIDS) were grown in vitro with added T-cell growth factor and assayed for the expression and release of human T-lymphotropic retroviruses (HTLV).
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Administration of 3'-azido-3'-deoxythymidine, an inhibitor of htlv-iii/lav replication, to patients with aids or aids-related complex
Robert Yarchoan,Kent J. Weinhold,H. Kim Lyerly,Edward P. Gelmann,Robert M. Blum,Gene M. Shearer,Hiroaki Mitsuya,Jerry M. Collins,Charles E. Myers,Raymond W. Klecker,Phillip D. Markham,David T. Durack,S. Nusinoff Lehrman,David W. Barry,Margaret A. Fischl,Robert C. Gallo,Dani P. Bolognesi,Samuel Broder +17 more
TL;DR: 4 dose regimens of 3'-azido-3'-deoxythymidine (AZT), a thymidine analogue with potent anti-viral activity against HTLV-III in vitro, were examined in 19 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC).
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Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma
Barbara Ensoli,R Gendelman,Phillip D. Markham,Valeria Fiorelli,Sandra Colombini,Mark Raffeld,Aurelio Cafaro,Hsiao-Kuey Chang,John N. Brady,Robert C. Gallo +9 more
TL;DR: Basic fibroblast growth factor and human immunodeficiency virus type 1 (HIV-1) Tat protein synergize in inducing angiogenic Kaposi's sarcoma-like lesions in mice, which may explain the higher frequency and aggressiveness of this form of KS.
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HTLV-III in saliva of people with AIDS-related complex and healthy homosexual men at risk for AIDS
Jerome E. Groopman,Saira Salahuddin,M. G. Sarngadharan,Phillip D. Markham,Matthew A. Gonda,Ann Sliski,Robert C. Gallo +6 more
TL;DR: Peripheral blood leukocytes and saliva from 20 individuals, including four with the acquired immune deficiency syndrome (AIDS), ten with AIDS-related complex (ARC), and six healthy homosexual males at risk for AIDS, were compared as sources of transmissible human T-cell leukemia (lymphotropic) virus type III (HTLV-III), the virus found to be the etiologic agent of AIDS.
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Restricted expression of human T-cell leukemia--lymphoma virus (HTLV) in transformed human umbilical cord blood lymphocytes.
Saira Salahuddin,Phillip D. Markham,Flossie Wong-Staal,Genoveffa Franchini,V. S. Kalyanaraman,Robert C. Gallo +5 more
TL;DR: Multiple immortalized, non-producer, human umbilical cord blood lymphocyte cultures developed by cocultivation or fusion of fresh cells with T cells cultured from leukemia-lymphoma patients are described.