P
Phillip J. Robinson
Researcher at Children's Medical Research Institute
Publications - 236
Citations - 13883
Phillip J. Robinson is an academic researcher from Children's Medical Research Institute. The author has contributed to research in topics: Dynamin & Phosphorylation. The author has an hindex of 60, co-authored 236 publications receiving 12759 citations. Previous affiliations of Phillip J. Robinson include University of Newcastle & Baylor College of Medicine.
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Journal ArticleDOI
Protein composition of catalytically active human telomerase from immortal cells.
Scott B. Cohen,Mark E. Graham,George O. Lovrecz,Nicolai Bache,Phillip J. Robinson,Roger R. Reddel +5 more
TL;DR: P purified human telomerase is purified ∼108-fold, with the final elution dependent on the enzyme's ability to catalyze nucleotide addition onto a DNA oligonucleotide of telomeric sequence, thereby providing specificity for catalytically active telomersase.
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Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition.
Lisa von Kleist,Wiebke Stahlschmidt,Haydar Bulut,Kira Gromova,Dmytro Puchkov,Mark J. Robertson,Kylie A. MacGregor,Nikolay Tomilin,Arndt Pechstein,Arndt Pechstein,Ngoc Chau,Megan Chircop,Jennette A. Sakoff,Jens Peter von Kries,Wolfram Saenger,Hans-Georg Kräusslich,Oleg Shupliakov,Phillip J. Robinson,Adam McCluskey,Volker Haucke,Volker Haucke +20 more
TL;DR: Pitstop-induced inhibition of clathrin TD function acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling, suggesting that the clathin TD regulates coated pit dynamics.
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SIMAC (Sequential Elution from IMAC), a Phosphoproteomics Strategy for the Rapid Separation of Monophosphorylated from Multiply Phosphorylated Peptides
TL;DR: A simple and rapid strategy, SIMAC (sequential elution from IMAC), for sequential separation of monophosphorylation peptides and multiply phosphorylated peptides from highly complex biological samples is reported.
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A rapid Percoll gradient procedure for preparation of synaptosomes
TL;DR: This protocol has advantages over other procedures in terms of speed and by producing relatively homogeneous synaptosomes, minimizing the presence of synaptic and glial plasma membranes and extrasynaptosomal mitochondria.
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The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis.
TL;DR: The phosphorylation cycle of the dephosphins might regulate SVE by targeting the proteins to sites of action and by stimulating the assembly of several large essential endocytic protein complexes.