P
Pierrick J. Fournier
Researcher at Indiana University – Purdue University Indianapolis
Publications - 3
Citations - 158
Pierrick J. Fournier is an academic researcher from Indiana University – Purdue University Indianapolis. The author has contributed to research in topics: Melanoma & Transforming growth factor. The author has an hindex of 1, co-authored 3 publications receiving 153 citations.
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Journal ArticleDOI
GLI2-Mediated Melanoma Invasion and Metastasis
Vasileia-Ismini Alexaki,Delphine Javelaud,Delphine Javelaud,Delphine Javelaud,Léon C van Kempen,Khalid S. Mohammad,Sylviane Dennler,Sylviane Dennler,Sylviane Dennler,Flavie Luciani,Flavie Luciani,Keith S. Hoek,Patricia Juárez,James S. Goydos,Pierrick J. Fournier,Claire Sibon,Corine Bertolotto,Franck Verrecchia,Simon Saule,Simon Saule,Véronique Delmas,Véronique Delmas,Robert Ballotti,Lionel Larue,Lionel Larue,Philippe Saiag,Theresa A. Guise,Alain Mauviel,Alain Mauviel,Alain Mauviel +29 more
TL;DR: GLI2 was directly involved in driving melanoma invasion and metastasis in this preclinical study and was identified as a transcriptional target of TGF-beta signaling.
Book ChapterDOI
Transforming growth factor-β and its signaling pathway in skeletal complications of malignancy
G li 2-Mediated Melanoma i nvasion and Metastasis
Vasileia-Ismini Alexaki,Delphine Javelaud,Khalid S. Mohammad,Flavie Luciani,Keith S. Hoek,James S. Goydos,Pierrick J. Fournier,Claire Sibon,Corine Bertolotto,Franck Verrecchia,Simon Saule,Veronique Delmas,Robert Ballotti,Lionel Larue,Philippe Saiag,Theresa A. Guise,Alain Mauviel +16 more
TL;DR: Within human melanoma lesions, GLI2 expression was heterogeneous, associated with tumor regions in which E-cadherin was lost and increased in the most aggressive tumors and MMP secretion in vitro and the development of experimental bone metastases in mice.