P
Pieter Van den Abbeele
Researcher at Ghent University
Publications - 105
Citations - 4433
Pieter Van den Abbeele is an academic researcher from Ghent University. The author has contributed to research in topics: Gut flora & Prebiotic. The author has an hindex of 25, co-authored 84 publications receiving 3194 citations.
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Journal ArticleDOI
A four-strain probiotic exerts positive immunomodulatory effects by enhancing colonic butyrate production in vitro.
Frédéric Moens,Pieter Van den Abbeele,Abdul Basit,Cornelius C. Dodoo,Rangan Chatterjee,Barry Smith,Simon Gaisford +6 more
TL;DR: The results indicate that the probiotic species alone do not result in a clinical effect; rather, they facilitate modulation of the gut microbiota composition and metabolic activity thereby influencing the immune response.
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Effects of Human Milk Oligosaccharides on the Adult Gut Microbiota and Barrier Function.
Tanja Šuligoj,Louise Kristine Vigsnæs,Pieter Van den Abbeele,Athanasia Apostolou,Katia Karalis,George M. Savva,Bruce McConnell,Nathalie Juge +7 more
TL;DR: Data show that, in addition to their bifidogenic activity, HMOs have the capacity to modulate immune function and the gut barrier, supporting the potential of H MOs to provide health benefits in adults.
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Intestinal colonization: how key microbial players become established in this dynamic process: microbial metabolic activities and the interplay between the host and microbes
TL;DR: Deciphering microbial signatures and their metabolites that govern short and long‐term equilibrium, as well as imbalances in host‐microbial relationships, may provide novel diagnostic tools and or therapeutic targets for specific disorders associated with intestinal dysbiosis and loss of homeostasis.
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In vitro model to study the modulation of the mucin-adhered bacterial community.
Pieter Van den Abbeele,Charlotte Grootaert,Sam Possemiers,Willy Verstraete,Kim Verbeken,Tom Van de Wiele +5 more
TL;DR: An in vitro adhesion assay was developed to study the mucin colonization of bacteria from the mixed microbial communities of the Simulator of the Human Intestinal Microbial Ecosystem and showed that bacterial adhesion to mucin agar is a matter of both non-specific and specific interactions.
Journal ArticleDOI
Arabinoxylo-Oligosaccharides and Inulin Impact Inter-Individual Variation on Microbial Metabolism and Composition, Which Immunomodulates Human Cells
Pieter Van den Abbeele,Bernard Taminiau,Iris Pinheiro,Cindy Duysburgh,Heidi Jacobs,Loek Pijls,Massimo Marzorati +6 more
TL;DR: Fecal batch fermentations coupled to cocultures of epithelial cells and macrophages were used to compare how arabinoxylo-oligosaccharides (AXOS) and inulin modulate gut microbial activity and composition of three different human donors and subsequently the epithelial permeability and immune response.