R
Rafael Fonseca
Researcher at Mayo Clinic
Publications - 7
Citations - 815
Rafael Fonseca is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Plasma cell leukemia & Multiple myeloma. The author has an hindex of 6, co-authored 7 publications receiving 720 citations.
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Journal ArticleDOI
Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group
C. Fernández de Larrea,Robert A. Kyle,Brian G.M. Durie,Heinz Ludwig,Saad Z. Usmani,David H. Vesole,Roman Hájek,J F San Miguel,O. Sezer,Pieter Sonneveld,Shaji Kumar,Anuj Mahindra,Raymond L. Comenzo,Antonio Palumbo,A. Mazumber,KC Anderson,P. G. Richardson,Ashraf Badros,Jo Caers,Michele Cavo,Xavier Leleu,Meletios A. Dimopoulos,Chor S. Chim,Rik Schots,A. Noeul,Dorotea Fantl,Ulf-Henrik Mellqvist,Ola Landgren,Asher Chanan-Khan,Philippe Moreau,Rafael Fonseca,Giampaolo Merlini,J. J. Lahuerta,J. Bladé,Robert Z. Orlowski,Jatin J. Shah +35 more
TL;DR: It is proposed that the thresholds for diagnosis be re-examined and consensus recommendations are made for diagnosis, as well as, response and progression criteria.
Journal ArticleDOI
Genetic aberrations and survival in plasma cell leukemia.
Rodger E. Tiedemann,Natalia Gonzalez-Paz,Robert A. Kyle,Rafael Santana-Davila,Tammy Price-Troska,S Van Wier,Wee Joo Chng,Rhett P. Ketterling,Morie A. Gertz,Kim Henderson,P R Greipp,Angela Dispenzieri,Martha Q. Lacy,S V Rajkumar,P L Bergsagel,Alexander Keith Stewart,Rafael Fonseca +16 more
TL;DR: Overall pPCL and sPCL are different disorders with distinct natural histories, genetics and survival, and both show frequent N-RAS or K-Ras mutation.
Journal ArticleDOI
Plasma cell leukemia
Flavio Albarracin,Rafael Fonseca +1 more
TL;DR: The best induction regimen for PCL is not known and there is great variability in clinical practice, so patients are treated with induction therapy followed by hematopoietic cell transplantation (HCT) in those who are appropriate candidates for this approach.
Journal ArticleDOI
Primary plasma cell leukemia: Report of 17 new cases treated with autologous or allogeneic stem-cell transplantation and review of the literature
Steven Saccaro,Rafael Fonseca,Diana M Veillon,James D. Cotelingam,Mary L. Nordberg,Christopher Bredeson,Jonathan D. Glass,Reinhold Munker +7 more
TL;DR: 17 new cases of PPCL who underwent stem‐cell transplantation (SCT) are described, including 2 cases observed by the authors and 15 cases from the International Bone Marrow Transplant Registry (IBMTR).
Journal ArticleDOI
Plasma cell leukemia.
Suzanne R. Hayman,Rafael Fonseca +1 more
TL;DR: Induction with combination chemotherapy, followed by high-dose chemotherapy (preferably within the setting of a clinical trial), is the current recommended approach for eligible patients.