R
Ranjan Deka
Researcher at University of Cincinnati
Publications - 197
Citations - 10628
Ranjan Deka is an academic researcher from University of Cincinnati. The author has contributed to research in topics: Population & Allele. The author has an hindex of 52, co-authored 178 publications receiving 9856 citations. Previous affiliations of Ranjan Deka include University of Texas Health Science Center at Houston & Boston Children's Hospital.
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Journal ArticleDOI
Replication of genetic variants from genome-wide association studies with metabolic traits in an island population of the Adriatic coast of Croatia
Rebekah Karns,Ge Zhang,Nina Jeran,Dubravka Havas-Augustin,Saša Missoni,Wen Niu,Subba Rao Indugula,Guangyun Sun,Zijad Duraković,Nina Smolej Narančić,Pavao Rudan,Ranajit Chakraborty,Ranjan Deka +12 more
TL;DR: This study strongly replicated the association of FTO variants with obesity-related measures and TCF7L2 variants with T2D-related traits, and the estimated effect sizes were larger or comparable to published studies.
Journal ArticleDOI
Comparison of five tandem repeat loci between humans and chimpanzees.
TL;DR: Five tandem repeat loci were studied in humans and chimpanzees using VNTR probes derived from human DNA, finding shared alleles were found at three loci and were often the modal allele in one species but never in both.
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Human leptin locus (LEP) alleles and BMI in Samoans.
Stephen T. McGarvey,W Forrest,W Forrest,Daniel E. Weeks,Guangyun Sun,Diane T. Smelser,Joseph Tufa,Satupaitea Viali,Ranjan Deka +8 more
TL;DR: Findings indicate that the leptin 3′-tetranucleotide repeat is associated with high BMI in adult Samoans, with allele 226 having a low frequency in the high BMI group.
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Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia.
Rebekah Karns,Satupaitea Viali,John Tuitele,Guangyun Sun,Hong Cheng,Daniel E. Weeks,Stephen T. McGarvey,Ranjan Deka +7 more
TL;DR: It could be surmised that FTO is not likely a major obesity locus in Polynesian populations, as nominal associations between FTO variants and skeletal and obesity measures found in the Samoan population disappeared following corrections for multiple testing.
Journal ArticleDOI
Familial Intracranial Aneurysms: Is Anatomic Vulnerability Heritable?
Jason Mackey,Robert D. Brown,Charles J. Moomaw,Richard W. Hornung,Laura Sauerbeck,Daniel Woo,Tatiana Foroud,Dheeraj Gandhi,Dawn Kleindorfer,Matthew L. Flaherty,Irene Meissner,Craig S. Anderson,Guy Rouleau,E. Sander Connolly,Ranjan Deka,Daniel L. Koller,Todd Abruzzo,John Huston,Joseph P. Broderick +18 more
TL;DR: It was found that IA territorial concordance was higher when probands were compared with their own affected FDRs than with comparison FDRs, which suggests that anatomic vulnerability to IA formation exists.