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Rebecca L. Robker
Researcher at University of Adelaide
Publications - 117
Citations - 8992
Rebecca L. Robker is an academic researcher from University of Adelaide. The author has contributed to research in topics: Oocyte & Ovulation. The author has an hindex of 45, co-authored 107 publications receiving 7787 citations. Previous affiliations of Rebecca L. Robker include Monash University, Clayton campus & Baylor College of Medicine.
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Journal ArticleDOI
Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis
Piotr Sicinski,Joana Liu Donaher,Yan Geng,Susan B. Parker,Humphrey Gardner,Mary Y. Park,Rebecca L. Robker,Jo Anne S. Richards,Lynda K. McGinnis,John D. Biggers,John J. Eppig,Roderick T. Bronson,Stephen J. Elledge,Robert A. Weinberg +13 more
TL;DR: In ovarian granulosa cells, cyclin D2 is specifically induced by FSH via a cyclic-AMP-dependent pathway, indicating that expression of the various D-type cyclins is under control of distinct intracellular signalling pathways.
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Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases
Rebecca L. Robker,Darryl L. Russell,Lawrence L. Espey,John P. Lydon,Bert W. O'Malley,JoAnne S. Richards +5 more
TL;DR: The identification of two regulated proteases in the ovary, together with their abnormal expression in anovulatory PR knockout mice, suggests that each plays a critical role in follicular rupture and represents a major advance in the understanding of the proteolytic events that control ovulation.
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Hormone-Induced Proliferation and Differentiation of Granulosa Cells: A Coordinated Balance of the Cell Cycle Regulators Cyclin D2 and p27Kip1
TL;DR: It is indicated that FSH and estradiol regulate granulosa cell proliferation during the development of preovulatory follicles by increasing levels of cyclin D2 relative to p27Kip1 and that LH terminates follicular growth by down-regulating cycl in D2 concurrent with up-regulation of p27Cip1.
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Molecular mechanisms of ovulation: co-ordination through the cumulus complex
TL;DR: This review focuses on the recent advances in understanding of molecular mechanisms that commence after the gonadotrophin surge and culminate with release of the oocyte.
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Beta-Oxidation Is Essential for Mouse Oocyte Developmental Competence and Early Embryo Development
Kylie R. Dunning,Kara Cashman,Darryl L. Russell,Jeremy G. Thompson,Robert J. Norman,Rebecca L. Robker +5 more
TL;DR: The importance of lipid metabolism for oocyte developmental competence and early embryo development was demonstrated by assessing the rate of embryo development following inhibition or upregulation of beta-oxidation with etomoxir (an inhibitor of CPT1B) or l-carnitine, respectively.