R
Rebeqa Gunnarsson
Researcher at Lund University
Publications - 32
Citations - 1171
Rebeqa Gunnarsson is an academic researcher from Lund University. The author has contributed to research in topics: Chronic lymphocytic leukemia & IGHV@. The author has an hindex of 17, co-authored 30 publications receiving 1087 citations. Previous affiliations of Rebeqa Gunnarsson include Science for Life Laboratory & Uppsala University.
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Journal Article
Screening For Copy-Number Alterations And Loss-Of-Heterozygosity In Chronic Lymphocytic Leukemia - A Comparative Study Of Four Differently Designed, High Resolution Microarray Platforms
Rebeqa Gunnarsson,Johan Staaf,Mattias Jansson,Anne Marie Ottesen,H. Goeransson,Ulrika Liljedahl,Ulrik Ralfkiaer,Mahmoud Mansouri,Anne Mette Buhl,K. Ekstrom Smedby,Henrik Hjalgrim,A. C. Syvaenen,Åke Borg,Anders Isaksson,Jesper Jurlander,Gunnar Juliusson,Richard Rosenquist +16 more
TL;DR: Cross‐platform comparison revealed 29 concordantly detected CNAs, including known recurrent alterations, which confirmed that all platforms are powerful tools when screening for large aberrations, but detection of 32 additional regions present in 2–3 platforms illustrated a discrepancy in detection of small CNAs.
Journal ArticleDOI
Screening for copy‐number alterations and loss of heterozygosity in chronic lymphocytic leukemia—A comparative study of four differently designed, high resolution microarray platforms
Rebeqa Gunnarsson,Johan Staaf,Mattias Jansson,Anne Marie Ottesen,Hanna Göransson,Ulrika Liljedahl,Ulrik Ralfkiaer,Mahmoud Mansouri,Anne Mette Buhl,Karin E. Smedby,Henrik Hjalgrim,Ann-Christine Syvänen,Åke Borg,Anders Isaksson,Jesper Jurlander,Gunnar Juliusson,Richard Rosenquist +16 more
TL;DR: In this article, a cross-platform comparison revealed 29 concordantly detected copy-number alterations, including known recurrent alterations, which confirmed that all platforms are powerful tools when screening for large aberrations.
Journal ArticleDOI
Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia.
Rebeqa Gunnarsson,Larry Mansouri,Anders Isaksson,Hanna Göransson,Nicola Cahill,Mattias Jansson,Markus Rasmussen,Jeanette Lundin,Stefan Norin,Anne Mette Buhl,Karin E. Smedby,Henrik Hjalgrim,Karin Karlsson,Jesper Jurlander,Christian H. Geisler,Gunnar Juliusson,Richard Rosenquist +16 more
TL;DR: Whole-genome screening revealed a high frequency of genomic aberrations in newly diagnosed chronic lymphocytic leukemia and was associated with other markers of aggressive disease and commonly included the known recurrent aberration.
Journal ArticleDOI
Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients
Rebeqa Gunnarsson,Anders Isaksson,Mahmoud Mansouri,Håkan Göransson,Marianne Jansson,Nicola Cahill,Magnus Rasmussen,Johan Staaf,Jeanette Lundin,Stefan Norin,Anne Mette Buhl,Karin E. Smedby,Henrik Hjalgrim,Karin Karlsson,J. Jurlander,Gunnar Juliusson,Richard Rosenquist +16 more
TL;DR: Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia and a high-resolution genomic screening of newly diagnosed patients is recommended.
Journal ArticleDOI
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
Larry Mansouri,Lesley-Ann Sutton,Viktor Ljungström,Sina Bondza,Linda Arngården,Sujata Bhoi,Jimmy Larsson,Diego Cortese,Antonia Kalushkova,Karla Plevová,Erin Young,Rebeqa Gunnarsson,Elin Falk-Sörqvist,Peter Lönn,Alice F. Muggen,Xiao-Jie Yan,Brigitta Sander,Gunilla Enblad,Karin E. Smedby,Gunnar Juliusson,Chrysoula Belessi,Johan Rung,Nicholas Chiorazzi,Jonathan C. Strefford,Anton W. Langerak,Šárka Pospíšilová,Frederic Davi,Mats Hellström,Helena Jernberg-Wiklund,Paolo Ghia,Ola Söderberg,Kostas Stamatopoulos,Marcus Lars Vittorio Nilsson,Richard Rosenquist +33 more
TL;DR: In this paper, the authors performed targeted deep sequencing of 18 core complex genes within the NF-κB pathway in a discovery and validation CLL cohort totaling 315 cases and found that the most frequently mutated gene was NFKBIE (21/315 cases; 7%).