R
Rein Aasland
Researcher at University of Bergen
Publications - 66
Citations - 9102
Rein Aasland is an academic researcher from University of Bergen. The author has contributed to research in topics: Chromatin & Gene. The author has an hindex of 36, co-authored 64 publications receiving 8727 citations. Previous affiliations of Rein Aasland include National Institute for Medical Research & European Bioinformatics Institute.
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Journal ArticleDOI
The PHD finger: Implications for chromatin-mediated transcriptional regulation
Journal ArticleDOI
Structure of mammalian AMPK and its regulation by ADP
Bing Xiao,Matthew J. Sanders,Matthew J. Sanders,Elizabeth Underwood,Richard Heath,Faith V. Mayer,David Carmena,Chun-Xia Jing,Philip A. Walker,John F. Eccleston,Lesley F. Haire,Peter Saiu,Steven Howell,Rein Aasland,Stephen R. Martin,David Carling,Steven J. Gamblin +16 more
TL;DR: It is shown that ADP binding to just one of the two exchangeable AXP (AMP/ADP/ATP) binding sites on the regulatory domain protects the enzyme from dephosphorylation, although it does not lead to allosteric activation.
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ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins
Pål Puntervoll,Rune Linding,Christine Gemünd,Sophie Chabanis-Davidson,Morten Mattingsdal,Scott Cameron,David M. A. Martin,Gabriele Ausiello,Barbara Brannetti,Anna Costantini,Fabrizio Ferrè,Vincenza Maselli,Allegra Via,Gianni Cesareni,Francesca Diella,Giulio Superti-Furga,Lucjan Wyrwicz,Chenna Ramu,Caroline McGuigan,Rambabu Gudavalli,Ivica Letunic,Peer Bork,Leszek Rychlewski,Bernhard Kuster,Manuela Helmer-Citterich,William N. Hunter,Rein Aasland,Toby J. Gibson +27 more
TL;DR: ELM, the Eukaryotic Linear Motif server at http://elm.eu.org/, is a new bioinformatics resource for investigating candidate short non-globular functional motifs in eukaryosis proteins, aiming to fill the void in bio informatics tools.
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The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4
Assen Roguev,Daniel Schaft,Anna Shevchenko,W.W.M. Pim Pijnappel,Matthias Wilm,Rein Aasland,A. Francis Stewart +6 more
TL;DR: Eukaryotic Set1Cs are H3 lysine 4 methyltransferases and are related to trxG action through association with Ash2 homologues, thus adding a new specificity and a new subclass of SET domain proteins known to methyl transferases.
Journal ArticleDOI
FYVE fingers bind PtdIns(3)P
Jean Michel Gaullier,Anne Simonsen,Antonello D'Arrigo,Bjørn Bremnes,Harald Stenmark,Rein Aasland +5 more
TL;DR: The FYVE finger, an evolutionarily conserved double-zinc-binding domain, is identified as a protein structure that binds to PtdIns(3)P with high specificity.