R
Ricardo C. Guerrero-Ferreira
Researcher at Emory University
Publications - 44
Citations - 1680
Ricardo C. Guerrero-Ferreira is an academic researcher from Emory University. The author has contributed to research in topics: Cryo-electron microscopy & Fibril. The author has an hindex of 17, co-authored 40 publications receiving 1214 citations. Previous affiliations of Ricardo C. Guerrero-Ferreira include FEI Company & New Mexico State University.
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Journal ArticleDOI
Cryo-EM structure of alpha-synuclein fibrils.
Ricardo C. Guerrero-Ferreira,Nicholas M.I. Taylor,Daniel Mona,Philippe Ringler,Matthias E. Lauer,Roland Riek,Markus Britschgi,Henning Stahlberg +7 more
TL;DR: The structure of cytotoxic alpha-synuclein fibrils is determined by cryo-electron microscopy at a resolution of 3.4 Å and a hydrophobic cleft at one end of the fibril may have implications for fibrin elongation, and invites for the design of molecules for diagnosis and treatment of synucleinopathies.
Journal ArticleDOI
Structure of the T4 baseplate and its function in triggering sheath contraction
Nicholas M.I. Taylor,Nikolai S. Prokhorov,Nikolai S. Prokhorov,Ricardo C. Guerrero-Ferreira,Mikhail M. Shneider,Christopher Browning,Christopher Browning,Kenneth N. Goldie,Henning Stahlberg,Petr G. Leiman +9 more
TL;DR: The identity and function of a minimal set of components that is conserved in all contractile injection systems and show that the triggering mechanism is universally conserved are established.
Journal ArticleDOI
Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Ricardo C. Guerrero-Ferreira,Nicholas M.I. Taylor,Ana-Andreea Arteni,Pratibha Kumari,Daniel Mona,Philippe Ringler,Markus Britschgi,Matthias E. Lauer,Ali Makky,Joeri Verasdonck,Roland Riek,Ronald Melki,Beat H. Meier,Anja Böckmann,Luc Bousset,Henning Stahlberg +15 more
TL;DR: Two new polymorphic atomic structures of alpha-synuclein fibrils are reported, termed polymorphs 2a and 2b, at 3.0 Å and 3.4 Å resolution, which show a radically different structure compared to previously reported polymorphs.
Journal ArticleDOI
Alternative mechanism for bacteriophage adsorption to the motile bacterium Caulobacter crescentus
Ricardo C. Guerrero-Ferreira,Patrick H. Viollier,Bert Ely,Jeanne S. Poindexter,Maria Georgieva,Grant J. Jensen,Elizabeth R. Wright +6 more
TL;DR: Evidence is presented that the first interaction of the phage with the bacterial flagellum takes place through a filament on thephage head, which may systematically underlie the initial interactions of phages with their hosts in other systems and possibly represent a widespread mechanism of efficient phage propagation.
Journal ArticleDOI
Rational design of helical nanotubes from self-assembly of coiled-coil lock washers.
Chunfu Xu,Rui Liu,Anil K. Mehta,Ricardo C. Guerrero-Ferreira,Elizabeth R. Wright,Stanislaw Dunin-Horkawicz,Kyle L. Morris,Louise C. Serpell,Xiaobing Zuo,Joseph S. Wall,Vincent P. Conticello +10 more
TL;DR: Fluorescence studies of the interaction of 7HSAP1 with the solvatochromic fluorophore PRODAN indicated that the nanotubes could encapsulate shape-appropriate small molecules with high binding affinity.