R
Richard D. Newcomb
Researcher at Plant & Food Research
Publications - 123
Citations - 7319
Richard D. Newcomb is an academic researcher from Plant & Food Research. The author has contributed to research in topics: Gene & Pheromone. The author has an hindex of 42, co-authored 122 publications receiving 6526 citations. Previous affiliations of Richard D. Newcomb include University of Auckland & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
DAD2 Is an α/β Hydrolase Likely to Be Involved in the Perception of the Plant Branching Hormone, Strigolactone
Cyril Hamiaux,Revel S.M. Drummond,Bart J. Janssen,Susan E. Ledger,Janine M. Cooney,Richard D. Newcomb,Richard D. Newcomb,Kimberley C. Snowden +7 more
TL;DR: Observations suggest that DAD2 acts to bind the mobile strigolactone signal and then interacts with PhMAX2A during catalysis to initiate an SCF-mediated signal transduction pathway.
Journal ArticleDOI
A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly
Richard D. Newcomb,Peter M. Campbell,David L. Ollis,E. Cheah,Robyn Joyce Russell,John G. Oakeshott +5 more
TL;DR: In vitro expression of two natural and two synthetic chimeric alleles shows that the Asp137 substitution alone is responsible for both the loss of E3's carboxylesterase activity and the acquisition of a novel OP hydrolase activity.
Journal ArticleDOI
RNA interference in the light brown apple moth, Epiphyas postvittana (Walker) induced by double-stranded RNA feeding.
C. T. Turner,Marcus Davy,Robin M. MacDiarmid,Kim M. Plummer,Nigel P. Birch,Richard D. Newcomb +5 more
TL;DR: It is demonstrated in the horticultural pest, Epiphyas postvittana, that RNAi can be triggered by oral delivery of dsRNA to larvae, and Transcript levels of a larval gut carboxylesterase gene were reduced to less than half that of controls within 2 days of being fed EposCXE1 ds RNA.
Journal ArticleDOI
A genomics approach reveals that aroma production in apple is controlled by ethylene predominantly at the final step in each biosynthetic pathway
Robert J. Schaffer,Ellen N. Friel,Edwige J. F. Souleyre,Karen Bolitho,Kate Thodey,Susan E. Ledger,Judith H. Bowen,Jun-Hong Ma,Bhawana Nain,Daniel Cohen,Andrew P. Gleave,Ross N. Crowhurst,Bart J. Janssen,Jia-Long Yao,Richard D. Newcomb +14 more
TL;DR: This analysis suggests that the initial and final enzymatic steps with the biosynthetic pathways are important transcriptional regulation points for aroma production in apple.
Journal ArticleDOI
Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins.
Renee Smart,Aidan Kiely,Aidan Kiely,Morgan Beale,Ernesto Vargas,Colm Carraher,Andrew V. Kralicek,David L. Christie,Chen Chen,Richard D. Newcomb,Coral G. Warr +10 more
TL;DR: Drosophila Ors comprise a novel family of seven transmembrane receptors that in HEK293 cells signal by opening cation channels, through a mechanism that is largely independent of G proteins.