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Richard De Boer
Researcher at Peter MacCallum Cancer Centre
Publications - 69
Citations - 4110
Richard De Boer is an academic researcher from Peter MacCallum Cancer Centre. The author has contributed to research in topics: Breast cancer & Metastatic breast cancer. The author has an hindex of 22, co-authored 69 publications receiving 3596 citations. Previous affiliations of Richard De Boer include Marche Polytechnic University & Royal Melbourne Hospital.
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Journal ArticleDOI
Denosumab Compared With Zoledronic Acid for the Treatment of Bone Metastases in Patients With Advanced Breast Cancer: A Randomized, Double-Blind Study
Alison Stopeck,Allan Lipton,Jean-Jacques Body,Guenther G. Steger,Katia Tonkin,Richard De Boer,Mikhail Lichinitser,Yasuhiro Fujiwara,Denise A. Yardley,María Viniegra,Michelle Fan,Qi Jiang,Roger Dansey,Susie Jun,Ada Braun +14 more
TL;DR: With the convenience of a subcutaneous injection and no requirement for renal monitoring, denosumab represents a potential treatment option for patients with bone metastases.
Journal ArticleDOI
Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial
Miguel Martin,Frankie A. Holmes,Bent Ejlertsen,Suzette Delaloge,Beverly Moy,Hiroji Iwata,Gunter von Minckwitz,Stephen Chia,Janine Mansi,Carlos H. Barrios,Michael Gnant,Z Tomasevic,Neelima Denduluri,Robert Šeparović,Erhan Gokmen,Anna Bashford,Manuel Ruiz Borrego,Sung Bae Kim,Erik Jakobsen,Audrone Ciceniene,Kenichi Inoue,Friedrich Overkamp,Joan B Heijns,Anne C Armstrong,John S. Link,Anil A. Joy,Richard Bryce,Alvin Wong,Susan Moran,Bin Yao,Feng Xu,Alan Auerbach,Marc Buyse,A. Chan,A. Chan,Vernon Harvey,Rudolf Tomek,Nicholas J. Robert,Ira Gore,John W. Smith,Norikazu Masuda,S. Di Sean Kendall,William Graydon Harker,Katarína Petráková,Angel Guerrero Zotano,Amparo Ruiz Simon,Zora Neskovic Konstantinovic,Nicholas Iannotti,Pierfrancesco Tassone,Gladys Rodriguez,Noelia Jáñez Martinez,Carmen Crespo Massieu,Snezana Smickoska,Isil Somali,Ugur Yilmaz,Mirta Garcia Alonso,Adolfo Murias Rosales,Soeren Cold,Ann Knoop,Debra A. Patt,Beth A. Hellerstedt,Serafin Morales Murillo,Ingrid A. Mayer,Julie Ann Means-Powell,Rina Hui,Francis M. Senecal,Richard De Boer,Zhenzhou Shen,Adam Andrzej Luczak,Joanna W.Y. Chui,Janice Wing-hang Tsang,István Láng,Yoshiaki Rai,Yasuo Hozumi,Albert J. Ten Tije,Manish Bhandari,Cynthia Osborne,Shoichiro Ohtani,Kenji Higaki,Kenichi Watanabe,Kazunori Taguchi,Masato Takahashi,Sladjana Filipovic,Vincent Hansen,Vijayarama Phooshkooru Rao,Manish Gupta,Petar Petrov,Bruno Coudert,Zeljko Vojnovic,Zsofia Polya,Toshiko Miyaki,Naohito Yamamoto,Stephen Brincat,Krzysztof Lesniewski-Kmak,Ewa Chmielowska,Ruemu E. Birhiray,Marc L. Citron,Steven W. Papish,William R. Berry,Sven Tyge Langkjer,Jose Angel Garcia Saenz,Ana Arance,Noa Efrat,Tomasz Sarosiek,Lukasz Grzeda,Yvonne Manalo,Julie C. Smith,Irfan Vaziri,Tabitha Healey,Yasmin Rahim,Cynthia Luk,Brian Dingle,Sandra Franco,Peter Grundtvig Sorensen,Anjana Anand,Sarah Khan,George Fountzilas,Kenjiro Aogi,Satoru Shimizu,Milada Mikulova,Stanislav Spanik,Robert A. Somer,Patrick J. Flynn,Jermaine Coward,Paul N. Mainwaring,Guy Jerusalem,Carine Segura-Ojezzar,Christelle Levy,Thierry Delozier,David Khayat,Robert E. Coleman,Martin J. Rolles,Robert Maisano,M. Nardi,Yoshinori Ito,Perran Fulden Yumuk,Gul Basaran,Nazim Serdar Turhal,Mary J. Wilkinson,Nathan B. Green,Algis P. Sidrys,Sigrun Hallmeyer,Douglas J. Testori,Srikala S. Sridhar,Jose Chang,Qiang Sun,Carlos Jara-Sanchez,Xabier Rubio,Maria Lomas Garrido,Juan Rafael De La Haba Rodriguez,Antonia Perello Martorell,Antoni Avelia Mestre,Julio Rifa Ferrer,Sonia del Barco Berron,Zsuzsanna Nagy,Maki Tanaka,Young-Hyuck Im,Robert R. Carroll,Laura C. Dickerson,Joseph R. Mace,Ragene Rivera,Leonard M. Klein,Robert Ruxer,Sharon Wilks,Dusan Kotasek,Vasil Popov,Violina Taskova,Violetka Marinova-Venkova,Constanta Timcheva,Christine Desbiens,Jean-Pierre Ayoub,Debjani Grenier,Norbert Marschner,Hans Tesch,Hans-Joachim Lueck,Jan Janssen,Ingo Schwaner,Stine Wahlstrom,Eva Harder Brix,Susanne Vallentin,Dan Kristensen,Anna Andreeva,Vesna Glavicic,Isabel Calvo Plaza,A. Torres,Corinne Veyret,Jean-Pierre Bergerat,Emmanuelle Bourbouloux,Wendy Ann Ella,Hafiz Algurafi,Anne Robinson,Seung Jin Kim,Tetsuya Taguchi,Elona Juozaityte,Stanley Madretsma,Sandra Radema,Malgorzata Czerniawska-Meier,Wojciech Rogowski,Maria Wagnerova,Donald A. Richards,Elizabeth Tan-Chiu,Asskikis Vasileios,Charles Arthur Henderson,Viran Roger Holden,Xiaojia Wang,Zhongsheng Tong,Junlan Yang,Manuel Enrique Gonzalez,Mahdi Rezai,John Hackmann,Eduardo Martinez de Dueñas,Begoña Bermejo de las Heras,Louis Marie Dourthe,Dorothee Chocteau-Bouju,Philippe Bougnoux,Stylianos Kakolyris,Haralabos P. Kalofonos,Dimitrios Pectasidis,Ting Ying Ng,Gábor Pajkos,Eva Ezer Somogyine,Giuseppe Tonini,Dario Giuffrida,Shintaro Takao,Makoto Ishitobi,Hideo Inaji,Yutaka Tokuda,Katarzyna Wozniak,Dan Lungulescu,Yen-Shen Lu,King-Jen Chang,Julian Hill,Christopher Charles Croot,Albert Dekker,Neil D. Belman,Miguel Conde,Richard A. Michaelson,Kathleen Kemmer,Stephen Y. Chui,Shiuh-Wen Luoh,Kenneth Nahum,Andrew R. Greenspan,Joni C. Nichols,Carlos A. Encarnacion,Thomas M.J. Niederman,Theresa Lee,Roland Alexander,Robert Gordon,Antoanet Tomova,Daniel Rauch,R. A. Popescu,Gustavo Adolfo Rojas,Jaroslav Vanasek,Tanja Neunhoeffer,Jana Barinoff,Gerd Graffunder,Abenhardt Wolfgang,Peter Bojko,Bernhard Heinrich,Albert von der Assen,Bogovic Jurij Antonovic,Lene Adrian,Manuel Ramos Vazquez,Santiago Gonzalez Santiago,Véronique Diéras,J. Bishop,Timothy J. Perren,Ioannis Varthalitis,Dimitris Mavroudis,Vassilis Georgoulias,Louis W.C. Chow,Chung Cheung Thomas Yau,Raymond Hin-Suen Liang,Bela Piko,Agnes Wéber,Bella Kaufman,Karen Drumea,Francesco Nuzzo,Andrea de Matteis,Giacomo Cartenì,Eriko Tokunaga,Mayumi Ishida,Shinji Ohno,Nobuaki Sato,Katsumasa Kuroi,Reiki Nishimura,Junichiro Watanabe,Yoon Ji Choi,Kyong Hwa Park,Marek Z. Wojtukiewicz,Jacek Jassem,Niklas Loman,Sercan Askoy,Mustafa Kadri Altundag,Pinar Saip,Muhammad Amjad Ali,James L. Wade,Amy Jo Chien,Debra Brandt,Yelena Novik,Chirag Jani,Robert L. Rice,Yousuf A. R Gaffar,Mark R. Keaton,Rajesh Bajaj,Gretchen Kimmick,David Campbell,Theodore Turnquest,Sideras Lucas,Pierre Dube,Binghe Xu,Joerg Schilling,Klaus Apel,Peter Michael Vestlev,Brita Bjerregaard Jensen,Vera Haahr,Alvaro Rodriguez Lescure,Begona Grana Suarez,Cristina Saura Manich,Jean-Philippe Jacquin,Ahmed Samreen,Ion Boiangiu,Magdolna Dank,Cristina Falci,Antonio Jirillo,Saverio Cinieri,Takayuki Ueno,Fumiaki Sato,Hiroyasu Yamashiro,Tomoharu Sugie,Keun Seok Lee,Jung Sil Ro,In Hae Park,Anita Zarina Bustam,Malgorzata Suszko-Kazarnowicz,Artur Piktel,Krzysztof Krzemieniecki,Polizenia Georgeta Iorga,Yoon Sim Yap,Marian Kakalejcik,Alper Sevinc,Mustafa Ozguroglu,Shin-Cheh Chen,Richard H. Greenberg,Allan Daniel Eisemann,Robert Droder,M. Rashid Abbasi,Marina Vaysburd,Humberto Caldera,Barbara Haley,Erwin Robin,Roger C. Inhorn,David Hufnagel,Peter D. Kenyon,Ellen Spremulli,Paula Silverman,Sharad Jain,Robert Weigand,Jeroen Mebis,Tatyana Koynova,Bernard Lesperance,Jana Prausová,Claus-Henning Köhne,Andreas Schneeweiss,Christian Jackisch,Stefan Fuxius,Ricardo Cubedo Cervera,Ander Urruticoechea Ribate,Sonia Pernas Simon,Jose Valero Gallego,Angels Arcusa Lanza,Maria del Pilar Alvarez,Jesus Florian Gerico,Laurent Cany,Justin Stebbing,Dejan Labudovic,Damir Gugić,Damir Vrbanec,F. Roila,Sandro Barni,Paolo Bidoli,Hirofumi Mukai,Vanessa Bermudez,Alexandru Eniu,Barry C. Mirtsching,Emad Ibrahim,Joan Trey,Paul Francis Hergenroeder,Aftab Mahmood,Anneliese Gonzalez,Edward H. Kaplan,Stacy Ban,Dhimant Patel,Billy Clowney,Karen Hoelzer,Garry H. Schwartz,Mohamed Salkeni,Jame Abraham,Sunil Narula,Khaled Jabboury,Robert Scott Mocharnuk,Richard H. McDonough,David H. Sikes,Ronald H. Kawanchi,Larry Schlabach,Samuel Spence McCachren,Thomas M. Cosgriff,Luke Dreisbach,Angela DeMichele,Lawrence Pawl,Jennifer Lucas,Lowell C. Shinn,Nabiel Alkhouri,Manish Monga,Deborah L. Lindquist,Thomas C. Anderson,Humera Khurshid,Sabrina Witherby,Nicholette Erickson,Ann Traynor,Ron Bose,Timothy J. Pluard,Michael C. Jones,Sucharu Prakash,Fabio Volterra,Gerardo Capo,Lawrence E. Flaherty,Elaina Gartner,Said Baidas,Ian Okazaki,Bichlien Nguyen,Thomas Rakowski,Ira A Oliff,Joseph W. Leach,Daniel G. Anderson,Kendra Kubiak,Michaela Tsai,Philippe Vroman,Ines Deleu,Willem Lybaert,Marleen Borms,Félix Couture,Jonathan J. Wilson,Gordon Hunt,David R. Holland,Walter Mingrone,Shusen Wang,Donggeng Liu,Zefei Jiang,Vera Benesova,Martin Smakal,Petra Garnolova,Anne-Sophie Vesper,Monika Neumann,Wolfgang Janni,Cornelia Liedtke,Dorothea Fischer,Eva-Maria Grischke,Dietmar Seeger,Volker Moebus,Anita Prechtl,Juan Carlos Camara Toral,Alfonso Sanchez Munoz,Sonia Gonzalez Jimenez,Javier Cassinello Espinosa,Beatriz Cirauqui Cirauqui,Mireia Margeli Vila,Norberto Batista Lopez,Jose Ignacio Chacon Lopez-Muniz,Miguel Angel de la Cruz Mora,Audrey Mailliez,Laurence Vanlemmens,Damien Pouessel,Marc Espié,John Conibear,Rebecca Roylance,Adrian Harnett,David B. Geffen,Enzo Maria Ruggeri,Teresa Gamucci,Cees J. Van Groeningen,Renata Banas,Necati Alkis,Ming-Feng Hou,Amy K. Krie,Nandagopal S. Vrindavanam,Orion M. Howard,Dennis Citrin,Mark S. Morginstin,Ajit Desai,Ines J. Sanchez,David Allen Nixon,Patrick G. Beatty,Kathryn Edmiston,Marilyn McLaughlin,Jonathan D. Eneman,Cynthia A. Lynch,Edward O'Brien,Justin A. Call,Keith S. Lanier,Alison Conlin,Donald J. Brooks,Kristi McIntyre,Marc A. Saltzman,Michael J. Castine,Gregory L. Ortega,Young M. Choi,Craig H. Reynolds,Frankie Ann Brescia,Rita Kramer,Aimee D. Kohn,John P. Micha,Jessica M. Rhee,Satish Shah,David A. Riseberg,William Kevin Patterson,Jean-Paul Salmon,Chantal Andre,Alain Bols,Randal D'hondt,Sylvie Luce,Claire Nouwynck,Gino Pelgrims,Vincent Richard,Johan Verschuere,Kurt Geldhof,Clemens B. Caspar,Rongcheng Luo,Otakar Bednarik,Kathrin Schwedler,Marcus Schmidt,Romy Neumeister,Joachim Bischoff,Brigitte Rack,Roland Repp,Stefan Fries,Ralf Adrion,Volker Schulz,Peter Klare,Mahmoud Danei,Dirk Ossenbuhl,Jakob Manfred Kusche,Frank Griesinger,José Manuel Baena Cañada,Purificacion Martinez del Prado,David Machover,Didier Mayeur,Nathalie Trufflandier,Valerie Delecroix,Mireille Mousseau,Marie-Ange Mouret-Reynier,Jean-Marc Nabholtz,Anula Dharmapriya Chetiyawardana,Christos Papandreou,Lajos Hornyak,Zsolt Faluhelyi,Erzsebet Simo,Mario Di Palma,Francesco Cognetti,Gabriella Gorzegno,Luigi Dogliotti,Cesare Gridelli,Alfredo Falcone,Hector Soto Parra,Calogero Buscarino,Seock-Ah Im,Benito Sanchez Llamas,Wouter Dercksen,Franciscus Erdkamp,Jan B. Ruit,Hans Braun,Joanneke E.A. Portielje,Aydin Ciltas,Suleyman Buyukberber,Mustafa Benekli,Andrew J. Zahalsky,Rebecca Jaslow,Gary W. Thomas,Archana Maini,Israel Wiznitzer,Ali Khojasteh,Manuel Francisco Gonzalez,Lynn R. Kong,Aruna Padmanabhan,William A. Conkright,Sandra M. Swain,Douglas E. Faig,Kirti Jain,Ronald Yanagihara,Yvonne Ottaviano,Andrew Delmas,Heather A. Steele,Gordon K. Rainey,Penelope J. Harris,Jason K. Burris,Erik J. Rupard,Esther Tan,Pat W. Whitworth,Abby R. Bova,Ian Churchill Anderson,Mihran Shirinian,Caesar Tin-u,Timothy J. O'Rourke,Michael S. Roberts,Michael Francisco,A. Scott Pierson,Peter D. Byeff,Peter A. Kovach,John Robert Caton,Mark Urban Rarick,William G. Schimidt,Alison Stopeck,Rachel Swart,Maria Regina Carrillo Flores,Carlos A. Alemany,Brennely Lozada,Paul L. Weinstein,Wei Wang,Michael Porubcin,David M. Ellison,George F. Geils,Edgardo Rivera,Mahmoud Charif +622 more
TL;DR: 1 year of extended adjuvant therapy with neratinib, administered after chemotherapy and trastuzumab, significantly reduced the proportion of clinically relevant breast cancer relapses-ie, those that might lead to death, such as distant and locoregional relapses outside the preserved breast-without increasing the risk of long-term toxicity.
Journal ArticleDOI
Randomized Active-Controlled Phase II Study of Denosumab Efficacy and Safety in Patients With Breast Cancer-Related Bone Metastases
Allan Lipton,Guenther G. Steger,Jazmin Figueroa,Cristina Alvarado,Philippe Solal-Celigny,Jean-Jacques Body,Richard De Boer,Rossana Berardi,Pere Gascón,Katia Tonkin,Robert E. Coleman,Alexander H.G. Paterson,Mark C. Peterson,Michelle Fan,A. Kinsey,Susie Jun +15 more
TL;DR: Subcutaneous denosumab may be similar to IV BPs in suppressing bone turnover and reducing SRE risk in patients with breast cancer-related bone metastases not previously treated with intravenous bisphosphonates (IV BPs).
Journal ArticleDOI
Vandetanib Plus Pemetrexed for the Second-Line Treatment of Advanced Non–Small-Cell Lung Cancer: A Randomized, Double-Blind Phase III Trial
Richard De Boer,Oscar Arrieta,Chih-Hsin Yang,Maya Gottfried,Valorie F. Chan,Johann Raats,Filippo de Marinis,Raymond P. Abratt,Jürgen Wolf,Fiona H Blackhall,Peter Langmuir,Tsveta Milenkova,Jessica Read,Johan Vansteenkiste +13 more
TL;DR: The vandetanib combination showed a significantly higher objective response rate and a significant delay in the time to worsening of lung cancer symptoms versus the placebo arm as well as an acceptable safety profile in this patient population.
Journal ArticleDOI
Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial
Ian E. Krop,Ingrid A. Mayer,Vinod Ganju,Maura N. Dickler,Stephen R. D. Johnston,Serafin Morales,Denise A. Yardley,Bohuslav Melichar,Andres Forero-Torres,Soo-Chin Lee,Richard De Boer,Katarína Petráková,Susanne Vallentin,Edith A. Perez,Martine Piccart,Matthew J. Ellis,Eric P. Winer,Steven Gendreau,Mika K. Derynck,Mark R. Lackner,Gallia G. Levy,Jiaheng Qiu,Jing He,Peter Schmid +23 more
TL;DR: No difference was found in median progression-free survival between the pictilisib and placebo groups, and there was no difference when patients were analysed according to presence or absence.