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Richard L Zhu
Researcher at Johns Hopkins University School of Medicine
Publications - 12
Citations - 394
Richard L Zhu is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 3 publications receiving 108 citations.
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Journal ArticleDOI
The National COVID Cohort Collaborative (N3C): Rationale, Design, Infrastructure, and Deployment.
Melissa A. Haendel,Melissa A. Haendel,Christopher G. Chute,Tellen D. Bennett,David Eichmann,Justin Guinney,Warren A. Kibbe,Philip R. O. Payne,Emily R. Pfaff,Peter N. Robinson,Joel H. Saltz,Heidi Spratt,Christine Suver,John Wilbanks,Adam B. Wilcox,Andrew E. Williams,Chunlei Wu,Clair Blacketer,Robert L. Bradford,James J. Cimino,Marshall Clark,Evan W Colmenares,Patricia A Francis,Davera Gabriel,Alexis Graves,Raju Hemadri,Stephanie S Hong,George Hripscak,Dazhi Jiao,Jeffrey G. Klann,Kristin Kostka,Adam M Lee,Harold P Lehmann,Lora Lingrey,Robert T. Miller,Michele I. Morris,Shawn N. Murphy,Karthik Natarajan,Matvey B. Palchuk,Usman Sheikh,Harold R. Solbrig,Shyam Visweswaran,Anita Walden,Anita Walden,Kellie M Walters,Griffin M. Weber,Xiaohan Tanner Zhang,Richard L Zhu,Benjamin Amor,Andrew T Girvin,Amin Manna,Nabeel Qureshi,Michael G. Kurilla,Sam Michael,Lili M Portilla,Joni L Rutter,Christopher P. Austin,Ken R Gersing +57 more
TL;DR: The N3C has demonstrated that a multisite collaborative learning health network can overcome barriers to rapidly build a scalable infrastructure incorporating multiorganizational clinical data for COVID-19 analytics.
Posted ContentDOI
The National COVID Cohort Collaborative: Clinical Characterization and Early Severity Prediction
Tellen D. Bennett,Richard A. Moffitt,Janos Hajagos,Benjamin Amor,Adit Anand,Mark M. Bissell,Katie Rebecca Bradwell,Carolyn Bremer,James Brian Byrd,Alina Denham,Peter E. DeWitt,Davera Gabriel,Brian T. Garibaldi,Andrew T Girvin,Justin Guinney,Elaine L. Hill,Stephanie S Hong,Hunter Jimenez,Ramakanth Kavuluru,Kristin Kostka,Harold P Lehmann,Eli Levitt,Sandeep K. Mallipattu,Amin Manna,Julie A. McMurry,Michele I. Morris,John Muschelli,Andrew J. Neumann,Matvey B. Palchuk,Emily R. Pfaff,Zhenglong Qian,Nabeel Qureshi,Seth Russell,Heidi Spratt,Anita Walden,Anita Walden,Andrew E. Williams,Jacob T. Wooldridge,Yun Jae Yoo,Xiaohan Tanner Zhang,Richard L Zhu,Christopher P. Austin,Joel H. Saltz,Kenneth R. Gersing,Melissa A. Haendel,Melissa A. Haendel,Christopher G. Chute +46 more
TL;DR: The National COVID Cohort Collaborative (N3C) as discussed by the authors is the largest, most representative U.S. cohort of COVID-19 cases and controls to date.
Journal ArticleDOI
Synergies between Centralized and Federated Approaches to Data Quality: A Report from the National COVID Cohort Collaborative.
Emily R. Pfaff,Andrew T Girvin,Davera Gabriel,Kristin Kostka,Michele I. Morris,Matvey B. Palchuk,Harold P Lehmann,Benjamin Amor,Mark M. Bissell,Katie Rebecca Bradwell,Sigfried Gold,Stephanie S Hong,Johanna Loomba,Amin Manna,Julie A. McMurry,Emily Niehaus,Nabeel Quresh,Anita Walden,Xiaohan Tanner Zhang,Richard L Zhu,Richard A. Moffitt,Melissa Haendel,Christopher G. Chute +22 more
TL;DR: In this article, the authors developed a pipeline for ingesting, harmonizing, and centralizing data from 56 contributing data partners using four federated Common Data Models, and discovered 15 heuristics relating to source CDM conformance, demographics, COVID tests, conditions, encounters, measurements, observations, coding completeness and fitness for use.
Journal ArticleDOI
Harmonizing units and values of quantitative data elements in a very large nationally pooled electronic health record (EHR) dataset
Katie Bradwell,Jacob T. Wooldridge,Benjamin Amor,Tellen D. Bennett,A. Anand,C. Bremer,Yung Jae Yoo,Zhenglong Qian,Steven G. Johnson,Emily R. Pfaff,Andrew T. Girvin,Amin Manna,Emily Niehaus,Stephanie S Hong,Xiaohan Tanner Zhang,Richard L Zhu,Mark Bissell,Nabeel Qureshi,Joel H. Saltz,Melissa A. Haendel,Christopher G. Chute,Harold P Lehmann,Richard A. Moffitt +22 more
TL;DR: The harmonization and inference methods developed herein can serve as a resource for initiatives aiming to extract insight from heterogeneous EHR collections as unique properties of centralized data are harnessed to enable unit inference.
Journal ArticleDOI
Rapid Approximate Subset-Based Spectra Prediction for Electron Ionization–Mass Spectrometry
Richard L Zhu,Eric Michael Jonas +1 more
TL;DR: In this article , a method for predicting electron ionization-mass spectra (EI-MS) of small molecules that combines physically plausible substructure enumeration and deep learning is presented, called rapid approximate subset-based spectra prediction (RASSP).