Robert Nickl

TL;DR: The structural and functional connectivity profile of effective DBS to the subthalamic nucleus (STN) is identified and its ability to predict outcome in an independent cohort is tested.

TL;DR: Measured chronaxies and model data suggest, that pulse durations <60 μsec lead to a focusing of the neurostimulation effect on smaller diameter axons close to the electrode while avoiding stimulation of distant pyramidal tract fibers.

TL;DR: Probabilistic outcome brain mapping is presented on a large cohort of patients collected from several European centres to resolve the optimal stimulation volume within the pallidal region and finds a significant relation between motor outcome and the stimulation volume, but not the electrode location per se.

TL;DR: In a standardized setting, the semi-sitting position allowed a safe approach in vestibular schwannoma surgery and offers the advantage of bimanual tumor nerve handling by the surgeon and an optimal visualization of important functional structures.

TL;DR: Results lend insight into the mechanism of deep brain stimulation induced cognitive decline and suggest that connectivity-based heat maps may help identify patients at risk and who might benefit fromDeep brain stimulation reprogramming.