R
Rony Chanoch-Myers
Researcher at Weizmann Institute of Science
Publications - 7
Citations - 334
Rony Chanoch-Myers is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 3 publications receiving 54 citations.
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Journal ArticleDOI
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.
Toshiro Hara,Rony Chanoch-Myers,Nathan Mathewson,Nathan Mathewson,Chad Myskiw,Lyla Atta,Lillian Bussema,Lillian Bussema,Stephen W. Eichhorn,Stephen W. Eichhorn,Alissa C. Greenwald,Gabriela Sarti Kinker,Gabriela Sarti Kinker,Christopher Rodman,L. Nicolas Gonzalez Castro,Hiroaki Wakimoto,Orit Rozenblatt-Rosen,Xiaowei Zhuang,Xiaowei Zhuang,Jean Fan,Tony Hunter,Inder M. Verma,Kai W. Wucherpfennig,Kai W. Wucherpfennig,Aviv Regev,Aviv Regev,Mario L. Suvà,Mario L. Suvà,Itay Tirosh +28 more
TL;DR: In this paper, the mesenchymal subtype of glioblastoma is determined by both cancer cell-intrinsic alterations and extrinsic cellular interactions, but remains poorly understood.
Journal ArticleDOI
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis
Nathan Mathewson,Orr Ashenberg,Itay Tirosh,Simon Gritsch,Simon Gritsch,Elizabeth M. Perez,Sascha Marx,Livnat Jerby-Arnon,Rony Chanoch-Myers,Toshiro Hara,Toshiro Hara,Alyssa R. Richman,Alyssa R. Richman,Yoshinaga Ito,Jason Pyrdol,Mirco Friedrich,Kathrin Schumann,Kathrin Schumann,Michael J. Poitras,Prafulla C. Gokhale,L. Nicolas Gonzalez Castro,Marni E. Shore,Marni E. Shore,Christine M. Hebert,Christine M. Hebert,Brian A. Shaw,Heather L. Cahill,Matthew Drummond,Wubing Zhang,Olamide Olawoyin,Hiroaki Wakimoto,Orit Rozenblatt-Rosen,Orit Rozenblatt-Rosen,Priscilla K. Brastianos,X. Shirley Liu,Pamela S. Jones,Daniel P. Cahill,Matthew P. Frosch,David N. Louis,Gordon J. Freeman,Keith L. Ligon,Alexander Marson,Alexander Marson,E. Antonio Chiocca,David A. Reardon,David A. Reardon,Aviv Regev,Mario L. Suvà,Mario L. Suvà,Kai W. Wucherpfennig +49 more
TL;DR: In this paper, single-cell RNA sequencing (RNA-seq) was used to chart the gene expression and clonal landscape of tumor-infiltrating T cells across 31 patients with isocitrate dehydrogenase (IDH) wild-type glioblastoma and IDH mutant glioma.
Journal ArticleDOI
Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis
TL;DR: In this article , the co-occurrence of mesenchymal signatures and their associations with genetic and micro-environmental features were examined, and three main variants of MES states were found: hypoxia-related (MES-Hyp), astrocyte-related, and an intermediate state.
Journal ArticleDOI
Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours
Avishai Gavish,Michael Tyler,Alissa C. Greenwald,Rouven Hoefflin,D. Simkin,Roi Tschernichovsky,Chaya Barbolin,Tomer Antman,Daniel Kovarsky,Thomas F. Barrett,L. Nicolas Gonzalez Castro,Debdatta Halder,Rony Chanoch-Myers,Julie Laffy,Michael Mints,Adi Wider,Rotem Tal,Avishay Spitzer,Toshiro Hara,Maria Raitses-Gurevich,Chani Stossel,Talia Golan,Amit Tirosh,Mario L. Suvà,Sidharth V. Puram,Itay Tirosh +25 more
Posted ContentDOI
Mutant IDH Inhibitors Induce Lineage Differentiation in IDH-mutant Oligodendroglioma
Avishay Spitzer,Simon Gritsch,Simon Gritsch,Hannah R. Weisman,Hannah R. Weisman,L. Nicolas Gonzalez Castro,L. Nicolas Gonzalez Castro,Masashi Nomura,Masashi Nomura,Nicholas Druck,Nicholas Druck,Rony Chanoch-Myers,Christine K. Lee,Hiroaki Nagashima,Julie J. Miller,Isabel Arrillaga-Romany,David N. Louis,Hiroaki Wakimoto,Will Pisano,Patrick Y. Wen,Keith L. Ligon,Daniel P. Cahill,Mario L. Suvà,Mario L. Suvà,Itay Tirosh +24 more
TL;DR: In this article, the authors investigated the cellular hierarchies that drive oligodendrogliomas and found that IDH treatment induces a robust differentiation towards glial lineages, accompanied by a depletion of stem-like cells and a reduction of cell proliferation.