R
Rosemary J. Boyton
Researcher at Imperial College London
Publications - 128
Citations - 5339
Rosemary J. Boyton is an academic researcher from Imperial College London. The author has contributed to research in topics: Medicine & Epitope. The author has an hindex of 30, co-authored 100 publications receiving 3145 citations. Previous affiliations of Rosemary J. Boyton include National Institutes of Health & Royal Free Hospital.
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Journal ArticleDOI
Antibody response to first BNT162b2 dose in previously SARS-CoV-2-infected individuals.
Charlotte Manisty,Ashley Otter,Thomas A. Treibel,Áine McKnight,Daniel M. Altmann,Timothy Brooks,Mahdad Noursadeghi,Rosemary J. Boyton,Amanda Semper,James C. Moon +9 more
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Innate immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1).
Pascal F. Durrenberger,Anna Ettorre,Fatemah Kamel,Louise V. Webb,Malcolm J. W. Sim,Richard Nicholas,Omar Malik,Richard Reynolds,Rosemary J. Boyton,Daniel M. Altmann +9 more
TL;DR: The data presented here show very limited expression of NCR1+ NK cells in MS lesions, the majority ofNCR1 expression being accounted for by expression on astrocytes, compatible with a role of this cell-type and NCR 1 ligand/receptor interactions in the innate immune response in the CNS in MS patients.
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Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.
Catherine J. Reynolds,Corinna Pade,Joseph M Gibbons,David Butler,Ashley Otter,Katia Menacho,Marianna Fontana,Marianna Fontana,Angelique Smit,Jane E. Sackville-West,Teresa Cutino-Moguel,Mala K. Maini,Benjamin M. Chain,Mahdad Noursadeghi,Tim Brooks,Amanda Semper,Charlotte Manisty,Charlotte Manisty,Thomas A. Treibel,Thomas A. Treibel,James C. Moon,James C. Moon,UK COVIDsortium Investigators,Ana M. Valdes,Ana M. Valdes,Áine McKnight,Daniel M. Altmann,Rosemary J. Boyton +27 more
TL;DR: In this paper, the authors investigated if single dose vaccination, with or without prior infection, confers cross-protective immunity to variants of SARS-CoV-2 vaccine rollout has coincided with the spread of variants of concern.
Journal ArticleDOI
SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection.
TL;DR: In efforts to synthesize a clear understanding of SARS-CoV-2 protective immunity, antibody analysis has been paralleled by T cell studies across asymptomatic, mild and severe COVID-19.
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Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression
John D. Campbell,Karen F. Buckland,Sarah J. McMillan,Jennifer Kearley,William L. G. Oldfield,Lawrence J. Stern,Hans Grönlund,Marianne van Hage,Catherine J. Reynolds,Rosemary J. Boyton,Stephen P. Cobbold,A. Barry Kay,Daniel M. Altmann,Clare M. Lloyd,Mark Larché,Mark Larché +15 more
TL;DR: In vivo evidence of linked epitope suppression and IL-10 induction in both human allergic disease and a mouse model designed to closely mimic peptide therapy in humans is provided.