C
Catherine J. Reynolds
Researcher at Imperial College London
Publications - 43
Citations - 1689
Catherine J. Reynolds is an academic researcher from Imperial College London. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 17, co-authored 36 publications receiving 938 citations. Previous affiliations of Catherine J. Reynolds include Hammersmith Hospital & National Institutes of Health.
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Journal ArticleDOI
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.
Catherine J. Reynolds,Corinna Pade,Joseph M Gibbons,David Butler,Ashley Otter,Katia Menacho,Marianna Fontana,Marianna Fontana,Angelique Smit,Jane E. Sackville-West,Teresa Cutino-Moguel,Mala K. Maini,Benjamin M. Chain,Mahdad Noursadeghi,Tim Brooks,Amanda Semper,Charlotte Manisty,Charlotte Manisty,Thomas A. Treibel,Thomas A. Treibel,James C. Moon,James C. Moon,UK COVIDsortium Investigators,Ana M. Valdes,Ana M. Valdes,Áine McKnight,Daniel M. Altmann,Rosemary J. Boyton +27 more
TL;DR: In this paper, the authors investigated if single dose vaccination, with or without prior infection, confers cross-protective immunity to variants of SARS-CoV-2 vaccine rollout has coincided with the spread of variants of concern.
Journal ArticleDOI
Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression
John D. Campbell,Karen F. Buckland,Sarah J. McMillan,Jennifer Kearley,William L. G. Oldfield,Lawrence J. Stern,Hans Grönlund,Marianne van Hage,Catherine J. Reynolds,Rosemary J. Boyton,Stephen P. Cobbold,A. Barry Kay,Daniel M. Altmann,Clare M. Lloyd,Mark Larché,Mark Larché +15 more
TL;DR: In vivo evidence of linked epitope suppression and IL-10 induction in both human allergic disease and a mouse model designed to closely mimic peptide therapy in humans is provided.
Journal ArticleDOI
Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial
Edward S. Chambers,Claire S Byrne,Douglas J. Morrison,Kevin G Murphy,Tom Preston,Catriona Tedford,Isabel Garcia-Perez,Sofia Fountana,Jose Ivan Serrano-Contreras,Elaine Holmes,Catherine J. Reynolds,Jordie F Roberts,Rosemary J. Boyton,Daniel M. Altmann,Julie A. K. McDonald,Julian R. Marchesi,Arne N. Akbar,Natalie E. Riddell,Gareth A. Wallis,Gary Frost +19 more
TL;DR: These data demonstrate a distinctive physiological impact of raising colonic propionate delivery in humans, as improvements in insulin sensitivity promoted by IPE and inulin were accompanied with different effects on the plasma metabolome, gut bacterial populations and markers of systemic inflammation.
Journal ArticleDOI
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure
Catherine J. Reynolds,Corinna Pade,Joseph Gibbons,Diana Munoz Sandoval,George Joy,Nasim Forooghi,Charlotte Manisty,James C. Moon,Rosemary J. Boyton,Hakam Abbass,Aderonke Abiodun,Mashael Alfarih,Zoe Alldis,Daniel M. Altmann,Oliver E. Amin,Mervyn Andiapen,Jessica Artico,João B Augusto,Georgina L Baca,Sasha N. L. Bailey,Anish N Bhuva,Alex Boulter,Ruth Bowles,Olivia V Bracken,Ben O’Brien,Tim Brooks,Natalie Bullock,David Butler,Gabriella Captur,Olivia Carr,Nicola Champion,Carmen Chan,Aneesh Chandran,Tom Coleman,Jorge Couto de Sousa,Xose Couto-Parada,Eleanor Cross,Teresa Cutino-Moguel,Silvia D'Arcangelo,Rhodri H Davies,Brooke Douglas,Cecilia Di Genova,Keenan Dieobi-Anene,Mariana O. Diniz,Ana Gabriela Aguilar Ellis,Karen Feehan,M. Finlay,Marianna Fontana,Sasha Francis,David Gillespie,Derek W. Gilroy,Matt Hamblin,Gabriella Harker,Georgia C. Hemingway,Jacqueline Hewson,Wendy E. Heywood,Lauren M. Hickling,Bethany Hicks,Aroon D. Hingorani,Lee Howes,Ivie Itua,Victor Jardim,Wing-Yiu Jason Lee,Melanie Jensen,Jessica Jones,Meleri Jones,V. S. Kapil,Caoimhe Kelly,H. Kurdi,Jonathan Lambourne,Kai-Min Lin,Siyi Liu,Aaron Lloyd,Sarah Louth,Mala K. Maini,Vineela Mandadapu,Áine McKnight,Katia Menacho,C. Mfuko,Kevin Mills,Sebastian Millward,Oliver Mitchelmore,Christopher William Moon,Sam M. Murray,Mahdad Noursadeghi,Ashley Otter,Susana Palma,Ruth Parker,Kush Patel,Mihaela Pawarova,Steffen E. Petersen,Brian Piniera,Franziska P Pieper,Lisa Rannigan,Alicja Rapala,Amy Richards,Matthew Robathan,Joshua Rosenheim,Cathy Rowe,M Royds,Jane Sackville West,Genine Sambile,Nathalie Schmidt,Hannah Selman,Amanda Semper,Andreas Seraphim,Mihaela Simion,Angelique Smit,Michelle Sugimoto,Leo Swadling,Stephen Taylor,Nigel J. Temperton,Stephen Thomas,George Douglas Thornton,Thomas A. Treibel,Arthur Tucker,A. Varghese,Jessry Veerapen,Mohit Vijayakumar,Time Warner,Sophie Welch,Hannah White,Theresa Wodehouse,Lucinda Wynne,Dan Zahedi,Benjamin M. Chain +125 more
TL;DR: B and T cell immunity against previous variants of concern was enhanced in triple vaccinated individuals, but magnitude of T and B cell responses against B.1.1 .1.529 spike protein was reduced.
Journal ArticleDOI
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection.
Catherine J. Reynolds,Leo Swadling,Joseph M Gibbons,Corinna Pade,Melanie Jensen,Mariana O. Diniz,Nathalie M. Schmidt,David Butler,Oliver E. Amin,Sasha N. L. Bailey,Sam M. Murray,Franziska P Pieper,Stephen Taylor,Jessica Jones,Meleri Jones,Wing-Yiu Jason Lee,Joshua Rosenheim,Aneesh Chandran,George Joy,Cecilia Di Genova,Nigel J. Temperton,Jonathan Lambourne,Teresa Cutino-Moguel,Mervyn Andiapen,Marianna Fontana,Angelique Smit,Amanda Semper,Ben O’Brien,Ben O’Brien,Ben O’Brien,Benjamin M. Chain,Tim Brooks,Charlotte Manisty,Charlotte Manisty,Thomas A. Treibel,Thomas A. Treibel,James C. Moon,James C. Moon,COVIDsortium Investigators,Mahdad Noursadeghi,Daniel M. Altmann,Mala K. Maini,Áine McKnight,Rosemary J. Boyton +43 more
TL;DR: In this paper, the authors analyzed T cell and neutralizing antibody responses in 136 healthcare workers (HCW) 16-18 weeks after United Kingdom lockdown, 76 of whom had mild/asymptomatic SARS-CoV-2 infection captured by serial sampling.