A
Amanda Semper
Researcher at Public Health England
Publications - 44
Citations - 3048
Amanda Semper is an academic researcher from Public Health England. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 13, co-authored 32 publications receiving 1157 citations. Previous affiliations of Amanda Semper include Government of the United Kingdom.
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Journal ArticleDOI
COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.
Victoria Hall,Victoria Hall,Sarah Foulkes,Ayoub Saei,Nick Andrews,Nick Andrews,Blanche Oguti,Blanche Oguti,Andre Charlett,Andre Charlett,Andre Charlett,Edgar Wellington,Julia Stowe,Natalie Gillson,Ana Atti,Jasmin Islam,Ioannis Karagiannis,Katie Munro,Jameel Khawam,Meera Chand,Colin S Brown,Mary Ramsay,Mary Ramsay,Jamie Lopez-Bernal,Susan Hopkins,Susan Hopkins,N Andrews,A Atti,H Aziz,Tim Brooks,CS Brown,D Camero,C Carr,MA Chand,A Charlett,Hayley Crawford,Michael J. Cole,J Conneely,Silvia D'Arcangelo,Joanna Ellis,S Evans,S Foulkes,N Gillson,Robin Gopal,L Hall,V J Hall,P Harrington,Susan R. Hopkins,Jacqueline Hewson,Katja Hoschler,D Ironmonger,J Islam,Meaghan Kall,I Karagiannis,O Kay,J Khawam,E King,Peter Kirwan,R Kyffin,Angie Lackenby,M Lattimore,Ezra Linley,J Lopez-Bernal,L Mabey,Reuben McGregor,Shahjahan Miah,Ejm Monk,K Munro,Z Naheed,A Nissr,A M O'Connell,B Oguti,Henrietta U. Okafor,S Organ,J Osbourne,Ashley Otter,Minal Patel,Steven Platt,D Pople,K Potts,M Ramsay,Julie V. Robotham,Sakib Rokadiya,Cathy Rowe,A Saei,G Sebbage,Amanda Semper,Madhumita Shrotri,Ruth Simmons,Alex Soriano,P Staves,S Taylor,Arthur Taylor,A Tengbe,S Tonge,Amoolya Vusirikala,Sarah Wallace,E Wellington,Maria Zambon,D Corrigan,M Sartaj,L Cromey,Sharon Campbell,K Braithwaite,L Price,L Haahr,S Stewart,ED Lacey,Linda Partridge,Gretchen A Stevens,Y Ellis,H Hodgson,C Norman,B Larru,S Mcwilliam,A Roynon,J Northfield,Stephen Winchester,P Cieciwa,Aditi Pai,P Bakker,C Loughrey,A Watt,F Adair,Adrian Hawkins,Alastair Grant,R Temple-Purcell,J Howard,N Slawson,C Subudhi,Shân Davies,A Bexley,R Penn,N Wong,G Boyd,A Rajgopal,A Arenas-Pinto,R Matthews,A Whileman,R Laugharne,J Ledger,Trevor J. Barnes,Chris Jones,N Osuji,N Chitalia,T Bailey,S Akhtar,G Harrison,S Horne,Naomi F. Walker,Ken Agwuh,V Maxwell,J Graves,Stephen R. Williams,A O'Kelly,P Ridley,A Cowley,H Johnstone,P Swift,Jane Democratis,Manjula Meda,S Brake,J Gunn,A Selassi,S Hams,V Irvine,Badrinathan Chandrasekaran,C Forsyth,J Radmore,C Thomas,Kevin K. Brown,Stuart K. Roberts,P Burns,K Gajee,T Lewis,T M Byrne,F Sanderson,Stephen R Knight,Emily MacNaughton,Bjl Burton,Helen V. Smith,R Chaudhuri,J Aeron-Thomas,K Hollinshead,R.J. Shorten,A Swan,C Favager,J Murira,S Baillon,S Hamer,Aarti Shah,J Russell,D Brennan,A Dave,Ajay Chawla,F Westwell,D Adeboyeku,Padmasayee Papineni,C Pegg,Martin S. Williams,Shazaad Ahmad,Alex Horsley,Christian Gabriel,K Pagget,G Maloney,J Ashcroft,I Del Rosario,R Crosby-Nwaobi,D Flanagan,D Dhasmana,Stephen J. Fowler,E Cameron,L Prentice,C Sinclair,V Bateman,K McLelland-Brooks,A Ho,Michael P. Murphy,A Cochrane,A Gibson,K. Black,K Tempeton,Stacey Donaldson,L Coke,N Elumogo,J Elliott,Debra Padgett,A Cross,Mariyam Mirfenderesky,S Joyce,I Sinanovic,M Howard,P Cowling,M Brazil,E Hanna,A Abdelrazik,S Brand,EA Sheridan,B Wadams,A Lloyd,J Mouland,J Giles,G Pottinger,H Coles,Mark Joseph,M Lee,S Orr,H Chenoweth,D Browne,Cressida Auckland,R Lear,Tabitha Mahungu,Alison Rodger,Simon Warren,D Brooking,S Pai,R Druyeh,Edward M. Smith,S. Stone,Sarah Meisner,D Delgado,E Underhill,L Keen,M Aga,P Domingos,S Gormley,Caroline Kerrison,S Birch,T DeSilva,L Allsop,S Ambalkar,M Beekes,S Jose,J Tomlinson,Sharen Painter,Claire Price,Justin Pepperell,Keith D. James,T Trinick,L Moore,Jeremy N. Day,A Boulos,I Knox,E Defever,D McCracken,K Gray,A Houston,Tim Planche,R Pritchard Jones,Diane Wycherley,Sara Bennett,J Marrs,K Nimako,Benjamin J. Stewart,SC Bain,N Kalakonda,S Khanduri,A Ashby,Matthew T. G. Holden,N Mahabir,J Harwood,Brendan A I Payne,K Court,Nicholas J. White,R Longfellow,L E Hughes,M E Green,M Halkes,P Mercer,A Roebuck,Eleri Wilson-Davies,L Gallego,Rajeka Lazarus,N Aldridge,Louise Berry,Frances L. Game,Timothy M Reynolds,Christopher W Holmes,Martin Wiselka,A Higham,M Booth,C Duff,J Alderton,D Hilton,J Powell,Alan Jackson,AJ Plant,Nada Ahmed,T Chin,M Z Qazzafi,A M Moody,Robert Tilley,T Donaghy,M O'Kane,K Shipman,R Sierra,Chetan Parmar,Gordon B. Mills,Daniel Harvey,Ywj Huang,J Birch,Louise Robinson,S Board,A Broadley,C Laven,N Todd,David W Eyre,Katie Jeffery,Susanna Dunachie,Christopher J A Duncan,Paul Klenerman,Lance Turtle,Helen Baxendale,Jonathan L. Heeney +353 more
TL;DR: The SIREN study as discussed by the authors showed that the BNT162b2 vaccine can prevent both symptomatic and asymptomatic infection in working-age adults in the UK.
Journal ArticleDOI
SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN).
V J Hall,Sarah Foulkes,Andre Charlett,Ana Atti,Edward J.M. Monk,Ruth Simmons,Edgar Wellington,M J Cole,Ayoub Saei,Blanche Oguti,Katie Munro,Sarah Wallace,Peter Kirwan,Madhumita Shrotri,Amoolya Vusirikala,Sakib Rokadiya,Meaghan Kall,Maria Zambon,Mary Ramsay,Tim Brooks,Colin S Brown,Meera Chand,Susan Hopkins,Nick Andrews,H Aziz,D Camero,C Carr,H Crawford,Michelle J Cole,J Conneely,Silvia D'Arcangelo,Joanna Ellis,S Evans,Natalie Gillson,Robin Gopal,L Hall,P Harrington,Jacqueline Hewson,Katja Hoschler,D Ironmonger,Jasmin Islam,Ioannis Karagiannis,O Kay,Jameel Khawam,E King,P Kirwan,R Kyffin,Angie Lackenby,M Lattimore,Ezra Linley,Jamie Lopez-Bernal,L Mabey,Reuben McGregor,Shahjahan Miah,Monk Emj.,Z Naheed,A Nissr,A M O'Connell,Henrietta U. Okafor,S Organ,J Osbourne,Ashley Otter,Monika Patel,Steven Platt,D Pople,K Potts,Julie V. Robotham,Cathy Rowe,G Sebbage,Amanda Semper,Alex Soriano,P Staves,S Taylor,Anne W. Taylor,A Tengbe,S Tonge,D Corrigan,M Sartaj,L Cromey,Sharon Campbell,K Braithwaite,L Price,L Haahr,S Stewart,ED Lacey,Linda Partridge,Gretchen A Stevens,Y Ellis,H Hodgson,C Norman,B Larru,S Mcwilliam,Stephen Winchester,P Cieciwa,Aditi Pai,C Loughrey,A Watt,F Adair,Adrian Hawkins,Alastair Grant,R Temple-Purcell,J Howard,N Slawson,C Subudhi,Shân Davies,A Bexley,R Penn,N Wong,G Boyd,A Rajgopal,A Arenas-Pinto,R Matthews,A Whileman,R Laugharne,J Ledger,Trevor J. Barnes,Carrie K. Jones,D Botes,N Chitalia,S Akhtar,G Harrison,S Horne,Naomi F. Walker,Ken Agwuh,V Maxwell,J Graves,Sue Williams,A O'Kelly,P Ridley,A Cowley,H Johnstone,P Swift,Jane Democratis,Manjula Meda,C Callens,S Beazer,S Hams,V Irvine,Badrinathan Chandrasekaran,C Forsyth,J Radmore,C Thomas,Kevin K. Brown,Sally A Roberts,P Burns,K Gajee,T M Byrne,F Sanderson,Stephen R Knight,Emily MacNaughton,Burton Bjl.,Helen V. Smith,R Chaudhuri,K Hollinshead,R.J. Shorten,A Swan,C Favager,J Murira,S Baillon,S Hamer,K Gantert,J Russell,D Brennan,A Dave,Ajay Chawla,F Westell,D Adeboyeku,Padmasayee Papineni,C Pegg,Martin S. Williams,Shazaad Ahmad,S Ingram,Christian Gabriel,K Pagget,G Maloney,J Ashcroft,I Del Rosario,R Crosby-Nwaobi,C Reeks,S Fowler,L Prentice,M Spears,G McKerron,K McLelland-Brooks,J Anderson,Stacey Donaldson,Kate Templeton,L Coke,N Elumogo,J Elliott,Debra Padgett,A Cross,Jonathan Price,S Joyce,I Sinanovic,M Howard,T Lewis,P Cowling,D Potoczna,S Brand,L Sheridan,B Wadams,A Lloyd,J Mouland,J Giles,G Pottinger,H Coles,M Joseph,M Lee,S Orr,H Chenoweth,Cressida Auckland,R Lear,Tabitha Mahungu,Alison Rodger,K Penny-Thomas,S Pai,J Zamikula,Edward M. Smith,S. Stone,E Boldock,D Howcroft,Carrie A. Thompson,M Aga,P Domingos,S Gormley,Caroline Kerrison,Laura Marsh,S Tazzyman,L Allsop,S Ambalkar,M Beekes,S Jose,J Tomlinson,A Jones,Claire Price,Justin Pepperell,M Schultz,Jeremy N. Day,A Boulos,E Defever,D McCracken,K Gray,A Houston,Tim Planche,R Pritchard Jones,D Wycherley,Sara Bennett,J Marrs,K Nimako,Benjamin J. Stewart,N Kalakonda,S Khanduri,A Ashby,Matthew T. G. Holden,N Mahabir,J Harwood,Brendan A I Payne,K Court,Nikki Staines,R Longfellow,M E Green,L E Hughes,M Halkes,P Mercer,A Roebuck,Eleri Wilson-Davies,L Gallego,Rajeka Lazarus,N Aldridge,Louise Berry,Frances L. Game,Timothy M Reynolds,Christopher W Holmes,Martin Wiselka,A Higham,M Booth,C Duff,J Alderton,H Jory,E Virgilio,T Chin,M Z Qazzafi,A M Moody,Robert Tilley,T Donaghy,K Shipman,R Sierra,Nick S. Jones,Gary H. Mills,Daniel Harvey,Huang Ywj.,J Birch,Louise Robinson,S Board,A Broadley,C Laven,N Todd,David W Eyre,Katie Jeffery,Susanna Dunachie,Christopher J A Duncan,Paul Klenerman,Lance Turtle,Helen Baxendale,Jonathan L. Heeney +305 more
TL;DR: The SARS-CoV-2 Immunity and Reinfection Evaluation study as mentioned in this paper showed that a previous history of SARS infection was associated with an 84% lower risk of infection, with median protective effect observed 7 months following primary infection.
Journal ArticleDOI
Antibody response to first BNT162b2 dose in previously SARS-CoV-2-infected individuals.
Charlotte Manisty,Ashley Otter,Thomas A. Treibel,Áine McKnight,Daniel M. Altmann,Timothy Brooks,Mahdad Noursadeghi,Rosemary J. Boyton,Amanda Semper,James C. Moon +9 more
Journal ArticleDOI
Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection
Victoria G Hall,Sarah Foulkes,Ferdinando Insalata,Peter Kirwan,Ayoub Saei,Ana Atti,Edgar Wellington,Jameel Khawam,Katie Munro,Michelle Cole,Caio Tranquillini,Andrew Taylor-Kerr,Nipunadi Hettiarachchi,Davina Calbraith,Noshin Sajedi,Iain D. Milligan,Yrene Themistocleous,Diane Corrigan,L. Cromey,Lesley Price,Sarah Stewart,Elen de Lacy,Christer Norman,Ezra Linley,Ashley Otter,Amanda Semper,Jacqueline Hewson,Silvia D'Arcangelo,Meera Chand,Colin S Brown,Tim Brooks,Jasmin Islam,Andre Charlett,Susan Hopkins +33 more
TL;DR: Two doses of BNT162b2 vaccine were associated with high short-term protection against SARS-CoV-2 infection; this protection waned considerably after 6 months and infection-acquired immunity boosted with vaccination remained high more than 1 year after infection.
Journal ArticleDOI
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.
Catherine J. Reynolds,Corinna Pade,Joseph M Gibbons,David Butler,Ashley Otter,Katia Menacho,Marianna Fontana,Marianna Fontana,Angelique Smit,Jane E. Sackville-West,Teresa Cutino-Moguel,Mala K. Maini,Benjamin M. Chain,Mahdad Noursadeghi,Tim Brooks,Amanda Semper,Charlotte Manisty,Charlotte Manisty,Thomas A. Treibel,Thomas A. Treibel,James C. Moon,James C. Moon,UK COVIDsortium Investigators,Ana M. Valdes,Ana M. Valdes,Áine McKnight,Daniel M. Altmann,Rosemary J. Boyton +27 more
TL;DR: In this paper, the authors investigated if single dose vaccination, with or without prior infection, confers cross-protective immunity to variants of SARS-CoV-2 vaccine rollout has coincided with the spread of variants of concern.