R
Rosie McEachan
Researcher at National Health Service
Publications - 32
Citations - 1104
Rosie McEachan is an academic researcher from National Health Service. The author has contributed to research in topics: Population & Exposome. The author has an hindex of 13, co-authored 30 publications receiving 691 citations. Previous affiliations of Rosie McEachan include Blackpool Victoria Hospital & Bradford Royal Infirmary.
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Journal ArticleDOI
Health and population effects of rare gene knockouts in adult humans with related parents.
Vagheesh M. Narasimhan,Karen A. Hunt,Dan Mason,Christopher L. Baker,Konrad J. Karczewski,Konrad J. Karczewski,Michael R. Barnes,Anthony H. Barnett,Christopher M. Bates,Srikanth Bellary,Nicholas A. Bockett,Kristina Giorda,Chris Griffiths,Harry Hemingway,Jia Zhilong,Ann M. Kelly,Hajrah A. Khawaja,Monkol Lek,Monkol Lek,Shane A. McCarthy,Rosie McEachan,Anne H. O’Donnell-Luria,Anne H. O’Donnell-Luria,Kenneth Paigen,Constantinos A. Parisinos,Eamonn Sheridan,Laura Southgate,Louise Tee,Mark G. Thomas,Yali Xue,Michael Schnall-Levin,Petko M. Petkov,Chris Tyler-Smith,Eamonn R. Maher,Eamonn R. Maher,Richard C. Trembath,Richard C. Trembath,Daniel G. MacArthur,Daniel G. MacArthur,John Wright,Richard Durbin,David A. van Heel +41 more
TL;DR: The results show that meiotic recombination sites are localized away from PRDM9-dependent hotspots, Thus, natural LOF variants inform on essential genetic loci and demonstratePRDM9 redundancy in humans.
Journal ArticleDOI
In-utero and childhood chemical exposome in six European mother-child cohorts
Line Småstuen Haug,Amrit Kaur Sakhi,Enrique Cequier,Maribel Casas,Léa Maitre,Xavier Basagaña,Sandra Andrusaityte,Georgia Chalkiadaki,Leda Chatzi,Muireann Coen,Jeroen de Bont,Audrius Dedele,Joane Ferrand,Regina Grazuleviciene,Juan R. González,Kristine B. Gutzkow,Hector C. Keun,Rosie McEachan,Helle Margrete Meltzer,Inga Petraviciene,Oliver Robinson,Pierre-Jean Saulnier,Rémy Slama,Jordi Sunyer,Jose Urquiza,Marina Vafeiadi,John Wright,Martine Vrijheid,Cathrine Thomsen +28 more
TL;DR: This study suggests that children across Europe are exposed to a wide range of environmental contaminants in fetal life and childhood including many with potential adverse effects, and that place of residence is a strong determinant of one's personal exposome.
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The Urban Exposome during Pregnancy and Its Socioeconomic Determinants
Oliver Robinson,Ibon Tamayo,Montserrat de Castro,Antònia Valentín,Lise Giorgis-Allemand,Norun Hjertager Krog,Gunn Marit Aasvang,Albert Ambros,Ferran Ballester,Pippa Bird,Leda Chatzi,Leda Chatzi,Leda Chatzi,Marta Cirach,Audrius Dėdelė,David Donaire-Gonzalez,Regina Gražuleviciene,Minas Iakovidis,Jesús Ibarluzea,Mariza Kampouri,Johanna Lepeule,Léa Maitre,Rosie McEachan,Bente Oftedal,Valérie Siroux,Rémy Slama,Euripides G. Stephanou,Jordi Sunyer,Jose Urquiza,Kjell Vegard Fjeldheim Weyde,John Wright,Martine Vrijheid,Mark J. Nieuwenhuijsen,Xavier Basagaña +33 more
TL;DR: Pregnant women of low SEP were exposed to higher levels of environmental hazards in some cities, but not others, which may contribute to inequities in child health and development.
Journal ArticleDOI
Influence of the Urban Exposome on Birth Weight
Mark J. Nieuwenhuijsen,Lydiane Agier,Xavier Basagaña,Jose Urquiza,Ibon Tamayo-Uria,Lise Giorgis-Allemand,Oliver Robinson,Valérie Siroux,Léa Maitre,Montserrat de Castro,Antonia Valentin,David Donaire,Payam Dadvand,Gunn Marit Aasvang,Norun Hjertager Krog,Per E. Schwarze,Leda Chatzi,Regina Grazuleviciene,Sandra Andrusaityte,Audrius Dedele,Rosie McEachan,John Wright,Jane West,Jesús Ibarluzea,Ferran Ballester,Martine Vrijheid,Rémy Slama +26 more
TL;DR: This investigation is the first large urban exposome study of birth weight that tests many environmental urban exposures and confirmed previously reported associations for NDVI and generated new hypotheses for a number of built-environment exposures.
Journal ArticleDOI
Identifying the Latent Failures Underpinning Medication Administration Errors: An Exploratory Study
TL;DR: This study is the first of its kind to identify the latent failures perceived to underpin medication errors in a systematic way and can be used as a platform for researchers to test the impact of organization-level patient safety interventions and to design proactive error management tools and incident reporting systems in hospitals.