R
Rupali Chopra
Researcher at Jawaharlal Nehru University
Publications - 17
Citations - 501
Rupali Chopra is an academic researcher from Jawaharlal Nehru University. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 12, co-authored 17 publications receiving 419 citations. Previous affiliations of Rupali Chopra include Shri Mata Vaishno Devi University.
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Journal ArticleDOI
Leprosy and the adaptation of human toll-like receptor 1.
Sunny H. Wong,Sailesh Gochhait,Dheeraj Malhotra,Fredrik Pettersson,Yik Y. Teo,Chiea Chuen Khor,Chiea Chuen Khor,Anna Rautanen,Stephen J Chapman,Tara C. Mills,Amit Kumar Srivastava,Aleksey A Rudko,Maxim B. Freidin,Maxim B. Freidin,V. P. Puzyrev,Shafat Ali,Shweta Aggarwal,Rupali Chopra,Belum Siva Nagi Reddy,Vijay K Garg,S. Roy,Sarah Meisner,Sunil K. Hazra,Bibhuti Saha,Sian Floyd,Brendan J. Keating,Cecilia Kim,Benjamin P. Fairfax,Julian C. Knight,Philip C. Hill,Richard A. Adegbola,Hakon Hakonarson,Paul E. M. Fine,Ramasamy Pitchappan,Rameshwar N. K. Bamezai,Adrian V. S. Hill,Fredrik O. Vannberg +36 more
TL;DR: An association analysis of more than 1,500 individuals from different case-control and family studies observations provide insight into the long standing host-pathogen relationship between human and mycobacteria and highlight the key role of the TLR pathway in infectious diseases.
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Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos.
Laura Girardi,Munevver Serdarogullari,Cristina Patassini,Maurizio Poli,Marco Fabiani,Silvia Caroselli,Onder Coban,Necati Findikli,Fazilet Kubra Boynukalin,Mustafa Bahceci,Rupali Chopra,Rita Canipari,Danilo Cimadomo,Laura Rienzi,Filippo Maria Ubaldi,Eva Hoffmann,Carmen Rubio,Carlos Simón,Antonio Capalbo +18 more
TL;DR: Evidence of the predominant mitotic origin of segmental aneuploidies in preimplantation embryos is provided and a risk stratification model is developed that can help post-test genetic counseling and that facilitates the decision-making process on clinical utilization of these embryos is facilitated.
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The clinicians´ dilemma with mosaicism-an insight from inner cell mass biopsies
Barbara Lawrenz,I El Khatib,Alberto Liñán,A Bayram,Ana Arnanz,Rupali Chopra,N. De Munck,Human M. Fatemi +7 more
TL;DR: The reliability of TE biopsy compared to ICM biopsy is almost perfect, but only substantial between cleavage stage biopsy and ICMBiopsy, and the obvious discordance between the three different approaches for PGT-A highlights the limitations of genetic testing.
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Investigation of DNA damage response and apoptotic gene methylation pattern in sporadic breast tumors using high throughput quantitative DNA methylation analysis technology
Ranjana Pal,Niloo Srivastava,Rupali Chopra,Sailesh Gochhait,Pawan Gupta,Neeraj Prakash,Gaurav Agarwal,Rameshwar N. K. Bamezai +7 more
TL;DR: The study indicates that methylation of DDR-apoptotic gene promoters in sporadic breast cancer is not a random phenomenon and since pathological epigenetic changes of the DDR-APoptotic genes are reversible modifications, these could further be targeted for therapeutic interventions.
Journal ArticleDOI
Genetic Variations and Interactions in Anti-inflammatory Cytokine Pathway Genes in the Outcome of Leprosy: A Study Conducted on a MassARRAY Platform
Shweta Aggarwal,Shafat Ali,Rupali Chopra,Amit Kumar Srivastava,Ponnusamy Kalaiarasan,Dheeraj Malhotra,Sailesh Gochhait,Vijay K Garg,Sambit Nath Bhattacharya,Rameshwar N. K. Bamezai +9 more
TL;DR: This study provides an interesting insight on the cumulative polygenic host component that regulates leprosy pathogenesis and investigates the association of 51 single-nucelotide polymorphisms in anti-inflammatory cytokines and receptors with susceptibility to leproSy.