V
V. P. Puzyrev
Researcher at Siberian State Medical University
Publications - 167
Citations - 2723
V. P. Puzyrev is an academic researcher from Siberian State Medical University. The author has contributed to research in topics: Population & Allele frequency. The author has an hindex of 21, co-authored 162 publications receiving 2303 citations. Previous affiliations of V. P. Puzyrev include USSR Academy of Medical Sciences & Academy of Sciences of the Czech Republic.
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Journal ArticleDOI
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
Florence Demenais,Florence Demenais,Patricia Margaritte-Jeannin,Patricia Margaritte-Jeannin,Kathleen C. Barnes,William O.C.M. Cookson,Janine Altmüller,Wei Ang,R. Graham Barr,Terri H. Beaty,Allan B. Becker,John Beilby,Hans Bisgaard,Unnur S. Bjornsdottir,Eugene R. Bleecker,Klaus Bønnelykke,Dorret I. Boomsma,Emmanuelle Bouzigon,Emmanuelle Bouzigon,Christopher E. Brightling,Myriam Brossard,Myriam Brossard,Guy Brusselle,Guy Brusselle,Esteban G. Burchard,Kristin M. Burkart,Andrew Bush,Andrew Bush,Moira Chan-Yeung,Kian Fan Chung,Kian Fan Chung,Alexessander Couto Alves,John A. Curtin,Adnan Custovic,Denise Daley,Johan C. de Jongste,Blanca E. Del-Rio-Navarro,Kathleen M. Donohue,Liesbeth Duijts,Celeste Eng,Johan G. Eriksson,Martin Farrall,Yuliya Fedorova,Bjarke Feenstra,Manuel A. R. Ferreira,Maxim B. Freidin,Zofia K. Z. Gajdos,Zofia K. Z. Gajdos,Jim Gauderman,Ulrike Gehring,Frank Geller,Jon Genuneit,Sina A. Gharib,Frank D. Gilliland,Raquel Granell,Penelope E. Graves,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Tari Haahtela,Susan R. Heckbert,Dick Heederik,Joachim Heinrich,Markku Heliövaara,John Henderson,Blanca E. Himes,Hiroshi Hirose,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Albert Hofman,Patrick G. Holt,Jouke J. Hottenga,Thomas J. Hudson,Thomas J. Hudson,Jennie Hui,Medea Imboden,Medea Imboden,Vladimir P. Ivanov,Vincent W. V. Jaddoe,Alan James,Alan James,Christer Janson,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Deborah Jarvis,Graham Jones,Ingileif Jonsdottir,Ingileif Jonsdottir,Pekka Jousilahti,Michael Kabesch,Mika Kähönen,David B. Kantor,A. S. Karunas,Elza Khusnutdinova,Gerard H. Koppelman,Anita L. Kozyrskyj,Eskil Kreiner,Michiaki Kubo,Rajesh Kumar,Rajesh Kumar,Ashok Kumar,Ashok Kumar,Ashok Kumar,Mikko Kuokkanen,Mikko Kuokkanen,Lies Lahousse,Lies Lahousse,Tarja Laitinen,Catherine Laprise,Mark Lathrop,Susanne Lau,Young-Ae Lee,Young-Ae Lee,Terho Lehtimäki,Sébastien Letort,Sébastien Letort,Albert M. Levin,Guo Li,Liming Liang,Laura R. Loehr,Stephanie J. London,Daan W. Loth,Ani Manichaikul,Ingo Marenholz,Ingo Marenholz,Fernando J. Martinez,Melanie C. Matheson,Rasika A. Mathias,Kenji Matsumoto,Hamdi Mbarek,Wendy L. McArdle,Mads Melbye,Mads Melbye,Mads Melbye,Erik Melén,Erik Melén,Deborah A. Meyers,Sven Michel,Hamida Mohamdi,Hamida Mohamdi,Arthur W. Musk,Arthur W. Musk,Rachel A. Myers,Maartje A.E. Nieuwenhuis,Emiko Noguchi,George T. O'Connor,George T. O'Connor,Ludmila M. Ogorodova,Cameron D. Palmer,Cameron D. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,Julie E. Park,Craig E. Pennell,Göran Pershagen,Göran Pershagen,Alexey Polonikov,Dirkje S. Postma,Nicole Probst-Hensch,Nicole Probst-Hensch,V. P. Puzyrev,Benjamin A. Raby,Olli T. Raitakari,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Stephen S. Rich,Colin F. Robertson,Isabelle Romieu,Muhammad T. Salam,Veikko Salomaa,Vivi Schlünssen,Robert A. Scott,P. A. Selivanova,Torben Sigsgaard,Angela Simpson,Valérie Siroux,Valérie Siroux,Lewis J. Smith,Maria Solodilova,Marie Standl,Kari Stefansson,Kari Stefansson,David P. Strachan,Bruno H. Stricker,Atsushi Takahashi,Philip J. Thompson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Carla M. T. Tiesler,Dara G. Torgerson,Tatsuhiko Tsunoda,André G. Uitterlinden,Ralf J. P. van der Valk,Amaury Vaysse,Amaury Vaysse,Sailaja Vedantam,Sailaja Vedantam,Andrea von Berg,Erika von Mutius,Judith M. Vonk,Johannes Waage,Nicholas J. Wareham,Scott T. Weiss,Wendy B. White,Magnus Wickman,Magnus Wickman,Elisabeth Widen,Gonneke Willemsen,L. Keoki Williams,Inge M. Wouters,James J. Yang,Jing Hua Zhao,Miriam F. Moffatt,Carole Ober,Dan L. Nicolae +216 more
TL;DR: A meta-analysis of GWAS studies for asthma from multiancestral cohorts identifies five new loci and finds that the asthma-associated loci are enriched near enhancer marks in immune cells, suggesting a major role of these loci in the regulation of immunologically related mechanisms.
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
Florence Demenais,Patricia Margaritte-Jeannin,Kathleen C. Barnes,William O.C.M. Cookson,Janine Altmueller,Wei Ang,R. Graham Barr,Terri H. Beaty,Allan B. Becker,John Beilby,Hans Bisgaard,Unnur S. Bjornsdottir,Eugene R. Bleecker,Klaus Bønnelykke,Dorret I. Boomsma,Emmanuelle Bouzigon,Christopher E. Brightling,Myriam Brossard,Guy Brusselle,Esteban G. Burchard,Kristin M. Burkart,Andrew Bush,Moira Chan-Yeung,Kian Fan Chung,Alexessander Couto Alves,John A. Curtin,Adnan Custovic,Denise Daley,Johan C. de Jongste,Blanca E. Del-Rio-Navarro,Kathleen M. Donohue,Liesbeth Duijts,Celeste Eng,Johan G. Eriksson,Martin Farrall,Yuliya Fedorova,Bjarke Feenstra,Manuel A. R. Ferreira,Maxim B. Freidin,Zofia K. Z. Gajdos,Jim Gauderman,Ulrike Gehring,Frank Geller,Jon Genuneit,Sina A. Gharib,Frank D. Gilliland,Raquel Granell,Penelope E. Graves,Daniel F. Gudbjartsson,Tari Haahtela,Susan R. Heckbert,Dick Heederik,Joachim Heinrich,Markku Heliövaara,John Henderson,Blanca E. Himes,Hiroshi Hirose,Joel N. Hirschhorn,Albert Hofman,Patrick G. Holt,Jouke J. Hottenga,Thomas J. Hudson,Jennie Hui,Medea Imboden,Vladimir P. Ivanov,Vincent W. V. Jaddoe,Alan James,Christer Janson,Marjo-Riitta Järvelin,Deborah Jarvis,Graham Jones,Ingileif Jonsdottir,Pekka Jousilahti,Michael Kabesch,Mika Kähönen,David B. Kantor,A. S. Karunas,Elza Khusnutdinova,Gerard H. Koppelman,Anita L. Kozyrskyj,Eskil Kreiner,Michiaki Kubo,Rajesh Kumar,Ashok Kumar,Mikko Kuokkanen,Lies Lahousse,Tarja Laitinen,Catherine Laprise,Mark Lathrop,Susanne Lau,Young-Ae Lee,Terho Lehtimäki,Sébastien Letort,Albert M. Levin,Guo Li,Liming Liang,Laura R. Loehr,Stephanie J. London,Daan W. Loth,Ani Manichaikul,Ingo Marenholz,Fernando J. Martinez,Melanie C. Matheson,Rasika A. Mathias,Kenji Matsumoto,Hamdi Mbarek,Wendy L. McArdle,Mads Melbye,Erik Melén,Deborah A. Meyers,Sven Michel,Hamida Mohamdi,Arthur W. Musk,Rachel A. Myers,Maartje A.E. Nieuwenhuis,Emiko Noguchi,George T. O'Connor,Ludmila M. Ogorodova,Cameron D. Palmer,Aarno Palotie,Julie E. Park,Craig E. Pennell,Göran Pershagen,Alexey Polonikov,Dirkje S. Postma,Nicole Probst-Hensch,V. P. Puzyrev,Benjamin A. Raby,Olli T. Raitakari,Adaikalavan Ramasamy,Stephen S. Rich,Colin F. Robertson,Isabelle Romieu,Muhammad T. Salam,Veikko Salomaa,Vivi Schlünssen,Robert A. Scott,P. A. Selivanova,Torben Sigsgaard,Angela Simpson,Valérie Siroux,Lewis J. Smith,Maria Solodilova,Marie Standl,Kari Stefansson,David P. Strachan,Bruno H. Stricker,Atsushi Takahashi,Philip J. Thompson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Carla M. T. Tiesler,Dara G. Torgerson,Tatsuhiko Tsunoda,André G. Uitterlinden,Ralf J. P. van der Valk,Amaury Vaysse,Sailaja Vedantam,Andrea von Berg,Erika von Mutius,Judith M. Vonk,Johannes Waage,Nicholas J. Wareham,Scott T. Weiss,Wendy B. White,Magnus Wickman,Elisabeth Widen,Gonneke Willemsen,L. Keoki Williams,Inge M. Wouters,James J. Yang,Jing Hua Zhao,Miriam F. Moffatt,Carole Ober,Dan L. Nicolae +174 more
Journal ArticleDOI
Disuniting Uniformity: A Pied Cladistic Canvas of mtDNA Haplogroup H in Eurasia
Eva Liis Loogväli,Urmas Roostalu,Boris Malyarchuk,Miroslava Derenko,Toomas Kivisild,Ene Metspalu,Kristiina Tambets,Maere Reidla,Helle Viivi Tolk,Jüri Parik,Erwan Pennarun,Sirle Laos,Arina Lunkina,M. V. Golubenko,Lovorka Barać,Marijana Peričić,Oleg Balanovsky,Vladislava Gusar,E. K. Khusnutdinova,Vadim Stepanov,V. P. Puzyrev,Pavao Rudan,Elena Balanovska,Elena Grechanina,Christelle Richard,Jean Paul Moisan,Andre Chaventre,Nicholas P. Anagnou,Kalliopi I. Pappa,Emmanuel Michalodimitrakis,Mireille Claustres,Mukaddes Gölge,Ilia Mikerezi,Esien Usanga,Richard Villems +34 more
TL;DR: The refinement of the phylogenetic resolution has allowed us to resolve a large number of homoplasies in phylogenetic trees of Hg H based on the first hypervariable segment (HVS-I) of mtDNA.
Journal ArticleDOI
Leprosy and the adaptation of human toll-like receptor 1.
Sunny H. Wong,Sailesh Gochhait,Dheeraj Malhotra,Fredrik Pettersson,Yik Y. Teo,Chiea Chuen Khor,Chiea Chuen Khor,Anna Rautanen,Stephen J Chapman,Tara C. Mills,Amit Kumar Srivastava,Aleksey A Rudko,Maxim B. Freidin,Maxim B. Freidin,V. P. Puzyrev,Shafat Ali,Shweta Aggarwal,Rupali Chopra,Belum Siva Nagi Reddy,Vijay K Garg,S. Roy,Sarah Meisner,Sunil K. Hazra,Bibhuti Saha,Sian Floyd,Brendan J. Keating,Cecilia Kim,Benjamin P. Fairfax,Julian C. Knight,Philip C. Hill,Richard A. Adegbola,Hakon Hakonarson,Paul E. M. Fine,Ramasamy Pitchappan,Rameshwar N. K. Bamezai,Adrian V. S. Hill,Fredrik O. Vannberg +36 more
TL;DR: An association analysis of more than 1,500 individuals from different case-control and family studies observations provide insight into the long standing host-pathogen relationship between human and mycobacteria and highlight the key role of the TLR pathway in infectious diseases.
Journal ArticleDOI
Meta-analysis identifies seven susceptibility loci involved in the atopic march
Ingo Marenholz,Ingo Marenholz,Jorge Esparza-Gordillo,Jorge Esparza-Gordillo,Franz Rüschendorf,Anja Bauerfeind,David P. Strachan,Ben D. Spycher,Hansjörg Baurecht,Patricia Margaritte-Jeannin,Patricia Margaritte-Jeannin,Annika Sääf,Marjan Kerkhof,Markus J. Ege,Svetlana Baltic,Melanie C. Matheson,Jin Li,Sven Michel,Wei Ang,Wendy L. McArdle,Andreas Arnold,Georg Homuth,Florence Demenais,Florence Demenais,Emmanuelle Bouzigon,Emmanuelle Bouzigon,Cilla Söderhäll,Göran Pershagen,Johan C. de Jongste,Dirkje S. Postma,Charlotte Braun-Fahrländer,Elisabeth Horak,Ludmila M. Ogorodova,V. P. Puzyrev,Elena Yu. Bragina,Thomas J. Hudson,Charles Morin,David L. Duffy,Guy B. Marks,Colin F. Robertson,Grant W. Montgomery,Bill Musk,Philip J. Thompson,Nicholas G. Martin,Alan L. James,Patrick M. A. Sleiman,Patrick M. A. Sleiman,Elina Toskala,Elke Rodriguez,Regina Fölster-Holst,Andre Franke,Wolfgang Lieb,Christian Gieger,Andrea Heinzmann,Ernst Rietschel,Thomas Keil,Thomas Keil,Sven Cichon,Markus M. Nöthen,Craig E. Pennell,Peter D. Sly,Carsten Oliver Schmidt,Anja Matanovic,Anja Matanovic,Valentin Schneider,Matthias Heinig,Matthias Heinig,Norbert Hubner,Patrick G. Holt,Patrick G. Holt,Susanne Lau,Michael Kabesch,S. Weidinger,Hakon Hakonarson,Hakon Hakonarson,Manuel A. R. Ferreira,Catherine Laprise,Maxim B. Freidin,Jon Genuneit,Gerard H. Koppelman,Erik Melén,Erik Melén,Marie Hélène Dizier,Marie Hélène Dizier,A. John Henderson,Young-Ae Lee,Young-Ae Lee +86 more
TL;DR: It is suggested that eczema may play an important role in the development of asthma after Eczema, and two novel loci specific for the combined ecZema plus asthma phenotype are reported, which are associated with allergic disease for the first time.