S
Sally A. Eaton
Researcher at Victor Chang Cardiac Research Institute
Publications - 17
Citations - 1367
Sally A. Eaton is an academic researcher from Victor Chang Cardiac Research Institute. The author has contributed to research in topics: GNAS complex locus & Offspring. The author has an hindex of 11, co-authored 17 publications receiving 1225 citations. Previous affiliations of Sally A. Eaton include University of Southampton & University of New South Wales.
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Journal ArticleDOI
Krüppel-like transcription factors: a functional family.
TL;DR: The biological roles of the Krüppel-like factor (Klfs) family of gene regulatory proteins as deduced from the gene ablation studies are outlined.
Journal ArticleDOI
Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells
Cheryl C. Y. Li,Sally A. Eaton,Paul E. Young,Maggie Lee,Rupert Shuttleworth,David T. Humphreys,Georges E. Grau,Valery Combes,Mary Bebawy,Joyce Gong,Susan Brammah,Michael E. Buckland,Catherine M. Suter +12 more
TL;DR: It is found that glioma microvesicles are predominantly of exosomal origin and contain complex populations of coding and noncoding RNAs in proportions that are distinct from those in the cells from which they are derived.
Journal ArticleDOI
Targeted Disruption of the Basic Krüppel-Like Factor Gene (Klf3) Reveals a Role in Adipogenesis
Nancy Sue,Briony H. A. Jack,Sally A. Eaton,Richard C. M. Pearson,Alister P. W. Funnell,Jeremy Turner,Robert Czolij,Gareth Denyer,Shisan Bao,Juan Carlos Molero-Navajas,Andrew C. Perkins,Yuko Fujiwara,Stuart H. Orkin,Kim S. Bell-Anderson,Merlin Crossley +14 more
TL;DR: The disruption of the murine basic Krüppel-like factor gene (Bklf or Klf3) is described and it is found that C/ebpα is derepressed in Klf2 and Ctbp knockout fibroblasts and adipocytes from Klf1 knockout mice, implicating Klf 3 and CtBP in controlling adipogenesis.
Journal ArticleDOI
Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity
Jennifer E. Cropley,Jennifer E. Cropley,Sally A. Eaton,Sally A. Eaton,Alastair Aiken,Paul E. Young,Eleni Giannoulatou,Joshua W. K. Ho,Joshua W. K. Ho,Michael E. Buckland,Simon P. Keam,Gyorgy Hutvagner,David T. Humphreys,Katherine G. Langley,Darren C. Henstridge,David I. K. Martin,David I. K. Martin,Mark A. Febbraio,Catherine M. Suter,Catherine M. Suter +19 more
TL;DR: It is found that F1 sons of obese founder males exhibited defects in glucose and lipid metabolism, but only upon a post-weaning dietary challenge, indicating that induced metabolic phenotypes may be propagated for a generation beyond any direct exposure to an inducing factor.
Journal ArticleDOI
A Network of Krüppel-like Factors (Klfs): Klf8 IS REPRESSED BY Klf3 AND ACTIVATED BY Klf1 IN VIVO*
Sally A. Eaton,Alister P. W. Funnell,Nancy Sue,Hannah R. Nicholas,Richard C. M. Pearson,Merlin Crossley +5 more
TL;DR: It is shown that Bklf or Klf3 (Basic Krüppel-like factor) represses the Klf8 (Krüpp-like Factor 8) gene in vivo, and an elaborate network of cross-talk within the K Alf family is revealed.