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Sarah Croessmann
Researcher at Vanderbilt University Medical Center
Publications - 39
Citations - 1586
Sarah Croessmann is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 15, co-authored 32 publications receiving 1195 citations. Previous affiliations of Sarah Croessmann include Johns Hopkins University & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Detection of cancer DNA in plasma of patients with early-stage breast cancer.
Julia A. Beaver,Danijela Jelovac,Sasidharan Balukrishna,Rory L. Cochran,Sarah Croessmann,Daniel J. Zabransky,Hong Yuen Wong,Patricia Valda Toro,Justin Cidado,Brian G. Blair,David Chu,Timothy F. Burns,Michaela J. Higgins,Vered Stearns,Lisa K. Jacobs,Mehran Habibi,Julie R. Lange,Paula J. Hurley,Josh Lauring,Dustin A. VanDenBerg,Jill Kessler,Stacie Jeter,Michael L. Samuels,Dianna Maar,Leslie Cope,Ashley Cimino-Mathews,Pedram Argani,Antonio C. Wolff,Ben Ho Park +28 more
TL;DR: This prospective study demonstrates accurate mutation detection in tumor tissues using ddPCR, and that ptDNA can be detected in blood before and after surgery in patients with early-stage breast cancer.
Journal ArticleDOI
Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer
Luigi Formisano,Yao Lu,Alberto Servetto,Ariella B. Hanker,Ariella B. Hanker,Valerie M. Jansen,Joshua A. Bauer,Dhivya R. Sudhan,Dhivya R. Sudhan,Angel Guerrero-Zotano,Sarah Croessmann,Yan Guo,Paula Gonzalez Ericsson,Kyungmin Lee,Mellissa J. Nixon,Luis J. Schwarz,Melinda E. Sanders,Teresa C. Dugger,Marcelo Rocha Cruz,Amir Behdad,Massimo Cristofanilli,Aditya Bardia,Joyce O'Shaughnessy,Rebecca J. Nagy,Richard B. Lanman,Nadia Solovieff,Wei He,Michelle Miller,Fei Su,Yu Shyr,Ingrid A. Mayer,Justin M. Balko,Carlos L. Arteaga,Carlos L. Arteaga +33 more
TL;DR: It is shown that FGFR1 amplification is a resistance mechanism to CDK4/6 inhibitor and endocrine therapy and that combined treatment with FGFR, CDK 4/6, and anti-estrogens is a potential therapeutic strategy in Era+ breast cancer tumors.
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ESR1 mutations in circulating plasma tumor DNA from metastatic breast cancer patients
David Chu,Costanza Paoletti,Christina L. Gersch,Dustin A. VanDenBerg,Daniel J. Zabransky,Rory L. Cochran,Hong Yuen Wong,Patricia Valda Toro,Justin Cidado,Sarah Croessmann,Bracha Erlanger,Karen Cravero,Kelly Kyker-Snowman,Berry Button,Heather A. Parsons,W. Brian Dalton,Riaz Gillani,Arielle Medford,Kimberly Aung,Nahomi Tokudome,Arul M. Chinnaiyan,Anne F. Schott,Dan R. Robinson,Karen S. Jacks,Josh Lauring,Paula J. Hurley,Daniel F. Hayes,James M. Rae,Ben Ho Park,Ben Ho Park +29 more
TL;DR: A high frequency of ESR1 mutations is shown using circulating plasma tumor DNA (ptDNA) from patients with metastatic breast cancer and it is suggested that blood can be used to identify additional mutations not found by sequencing of a single metastatic lesion.
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Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells
Hiroyuki Konishi,Morassa Mohseni,Akina Tamaki,Joseph P. Garay,Sarah Croessmann,Sivasundaram Karnan,Akinobu Ota,Hong Yuen Wong,Yuko Konishi,Yuko Konishi,Bedri Karakas,Khola Tahir,Abde M. Abukhdeir,John P. Gustin,Justin Cidado,Grace M. Wang,David Cosgrove,Rory L. Cochran,Danijela Jelovac,Michaela J. Higgins,Sabrina Arena,Sabrina Arena,Lauren Hawkins,Josh Lauring,Amy L. Gross,Christopher M. Heaphy,Yositaka Hosokawa,Edward Gabrielson,Alan K. Meeker,Kala Visvanathan,Pedram Argani,Kurtis E. Bachman,Ben Ho Park +32 more
TL;DR: It is shown that heterozygous BRCA1 inactivation results in genomic instability in nontumorigenic human breast epithelial cells in vitro and in vivo, and B RCA1 haploinsufficiency may accelerate hereditary breast carcinogenesis by facilitating additional genetic alterations.
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Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA
Patricia Valda Toro,Bracha Erlanger,Julia A. Beaver,Rory L. Cochran,Dustin A. VanDenBerg,Elizabeth Yakim,Karen Cravero,David Chu,Daniel J. Zabransky,Hong Yuen Wong,Sarah Croessmann,Heather A. Parsons,Paula J. Hurley,Josh Lauring,Ben Ho Park,Ben Ho Park +15 more
TL;DR: It is concluded that BCT tubes can prevent lysis and cellular release of genomic DNA of blood samples from cancer patients when stored at room temperature, and could therefore be of benefit for blood specimen collections in clinical trials.