Sasithon Pukrittayakamee

TL;DR: There is no parenteral formulation of the neuraminidase inhibitor oseltamivir, the most widely used anti-influenza virus drug, and both drugs were well tolerated alone and in combination.

TL;DR: In this article, the integrity of the gluconeogenic pathway in severe malaria using alanine metabolism as a measure was investigated, and it was shown that after intravenous infusion of alanines (0.3 g/kg) glucose increments (AUC[0-55 min]) were lower in patients with severe malaria than in those with moderately severe malaria (median=508 vs.

TL;DR: Antimalarial drugs, quinine, and the newly introduced compounds, halofantrine and mefloquine, can be relied upon nearly everywhere and offer a genuine prospect of reducing mortality from malaria in the tropics.

TL;DR: The hollow fiber bioreactor system adapted for the ex vivo culture of Plasmodiumfalciparum at high parasite densities opens new possibilities for the study of in vitro drug sensitivity under conditions mimicking in vivo pharmacokinetics, and the selection of anti-malarial drug resistance and associated parasite biological and genomic changes.

TL;DR: This study provides valuable information on the genetic polymorphisms in pmcsp isolates from Asia and advances the understanding of P. malariae population in Asia and Africa.