P
Podjanee Jittamala
Researcher at Mahidol University
Publications - 53
Citations - 3636
Podjanee Jittamala is an academic researcher from Mahidol University. The author has contributed to research in topics: Malaria & Medicine. The author has an hindex of 18, co-authored 41 publications receiving 2854 citations. Previous affiliations of Podjanee Jittamala include Novartis Institute for Tropical Diseases & Chiang Mai University.
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Journal ArticleDOI
Spread of Artemisinin Resistance in Plasmodium falciparum Malaria
Elizabeth A. Ashley,Mehul Dhorda,Rick M. Fairhurst,Chanaki Amaratunga,Pharath Lim,Seila Suon,Sokunthea Sreng,Jennifer M. Anderson,Mao S,Sam B,Chantha Sopha,Char Meng Chuor,Chea Nguon,Siv Sovannaroth,Sasithon Pukrittayakamee,Podjanee Jittamala,Kesinee Chotivanich,K Chutasmit,C Suchatsoonthorn,R Runcharoen,Tran Tinh Hien,Nguyen Thuy-Nhien,Thanh Nv,Nguyen Hoan Phu,Ye Htut,Han Kt,Kyin Hla Aye,Olugbenga A. Mokuolu,Rasaq Olaosebikan,Olaleke Oluwasegun Folaranmi,Mayfong Mayxay,Maniphone Khanthavong,Bouasy Hongvanthong,Paul N. Newton,M A Onyamboko,Caterina I. Fanello,Antoinette Tshefu,Neelima Mishra,Neena Valecha,Aung Pyae Phyo,François Nosten,Yi P,Rupam Tripura,Steffen Borrmann,Mahfudh Bashraheil,Judy Peshu,M A Faiz,Aniruddha Ghose,M A Hossain,Rasheda Samad,M. R. Rahman,Manal Hasan,Ashraful Islam,Olivo Miotto,Roberto Amato,Bronwyn MacInnis,Jim Stalker,Dominic P. Kwiatkowski,Zbynek Bozdech,Atthanee Jeeyapant,Phaik Yeong Cheah,Tharisara Sakulthaew,Jeremy Chalk,Benjamas Intharabut,Kamolrat Silamut,Lee Sj,Benchawan Vihokhern,Chanon Kunasol,Mallika Imwong,Joel Tarning,Taylor Wj,Shunmay Yeung,Charles J. Woodrow,Jennifer A. Flegg,Debashish Das,Jennifer L. Smith,Meera Venkatesan,Christopher V. Plowe,Kasia Stepniewska,Philippe J Guerin,Arjen M. Dondorp,Nicholas P. J. Day,Nicholas J. White +82 more
TL;DR: Prolonged courses of artemisinin-based combination therapies are currently efficacious in areas where standard 3-day treatments are failing, and the incidence of pretreatment and post-treatment gametocytemia was higher among patients with slow parasite clearance, suggesting greater potential for transmission.
Journal ArticleDOI
Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study
Rob W. van der Pluijm,Rob W. van der Pluijm,Mallika Imwong,Nguyen Hoang Chau,Nhu Thi Hoa,Nguyen Thuy-Nhien,Ngo Viet Thanh,Podjanee Jittamala,Borimas Hanboonkunupakarn,K Chutasmit,Chalermpon Saelow,Ratchadaporn Runjarern,Weerayuth Kaewmok,Rupam Tripura,Rupam Tripura,Thomas J. Peto,Thomas J. Peto,Sovann Yok,Seila Suon,Sokunthea Sreng,Sivanna Mao,Savuth Oun,Sovannary Yen,Chanaki Amaratunga,Dysoley Lek,Rekol Huy,Mehul Dhorda,Mehul Dhorda,Kesinee Chotivanich,Elizabeth A. Ashley,Elizabeth A. Ashley,Mavuto Mukaka,Mavuto Mukaka,Naomi Waithira,Naomi Waithira,Phaik Yeong Cheah,Phaik Yeong Cheah,Richard J. Maude,Richard J. Maude,Richard J. Maude,Roberto Amato,Richard D. Pearson,Richard D. Pearson,Sónia Gonçalves,Christopher G Jacob,William L Hamilton,Rick M. Fairhurst,Joel Tarning,Joel Tarning,Markus Winterberg,Markus Winterberg,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,Sasithon Pukrittayakamee,Sasithon Pukrittayakamee,Tran Tinh Hien,Nicholas P. J. Day,Nicholas P. J. Day,Olivo Miotto,Nicholas J. White,Nicholas J. White,Arjen M. Dondorp,Arjen M. Dondorp +62 more
TL;DR: Dihydroartemisinin-piperaquine is not treating malaria effectively across the eastern Greater Mekong subregion, and a highly drug-resistant P falciparum co-lineage is evolving, acquiring new resistance mechanisms, and spreading.
Journal ArticleDOI
Spiroindolone KAE609 for Falciparum and Vivax Malaria
Nicholas J. White,Sasithon Pukrittayakamee,Aung Pyae Phyo,R Rueangweerayut,François Nosten,Podjanee Jittamala,Atthanee Jeeyapant,Jay Prakash Jain,Gilbert Lefèvre,Ruobing Li,Baldur Magnusson,Thierry T. Diagana,F J Leong +12 more
TL;DR: KAE609, at dose of 30 mg daily for 3 days, cleared parasitemia rapidly in adults with uncomplicated P. vivax or P. falciparum malaria, supporting a once-daily oral dosing regimen.
Journal ArticleDOI
Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study
William L Hamilton,William L Hamilton,Roberto Amato,Roberto Amato,Rob W. van der Pluijm,Rob W. van der Pluijm,Christopher G Jacob,Huynh Hong Quang,Nguyen Thuy-Nhien,Tran Tinh Hien,Bouasy Hongvanthong,Keobouphaphone Chindavongsa,Mayfong Mayxay,Mayfong Mayxay,Huy Rekol,Rithea Leang,Cheah Huch,Lek Dysoley,Chanaki Amaratunga,Seila Suon,Rick M. Fairhurst,Rupam Tripura,Rupam Tripura,Thomas J. Peto,Thomas J. Peto,Yok Sovann,Podjanee Jittamala,Borimas Hanboonkunupakarn,Sasithon Pukrittayakamee,Sasithon Pukrittayakamee,Nguyen Hoang Chau,Mallika Imwong,Mehul Dhorda,Mehul Dhorda,Ranitha Vongpromek,Xin Hui S Chan,Xin Hui S Chan,Richard J. Maude,Richard J. Maude,Richard J. Maude,Richard D. Pearson,Richard D. Pearson,Thuy Nguyen,Kirk A. Rockett,Kirk A. Rockett,Eleanor Drury,Sónia Gonçalves,Nicholas J. White,Nicholas J. White,Nicholas P. J. Day,Nicholas P. J. Day,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,Arjen M. Dondorp,Arjen M. Dondorp,Olivo Miotto +55 more
TL;DR: After emerging and circulating for several years within Cambodia, the P falciparum KEL1/PLA1 co-lineage diversified into multiple subgroups and acquired new genetic features, including novel crt mutations.
Journal ArticleDOI
Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
Rob W. van der Pluijm,Rob W. van der Pluijm,Rob W. van der Pluijm,Rupam Tripura,Rupam Tripura,Richard M. Hoglund,Richard M. Hoglund,Aung Pyae Phyo,Dysoley Lek,Akhter ul Islam,Anupkumar R. Anvikar,Parthasarathi Satpathi,Sanghamitra Satpathi,Prativa K Behera,Amar Tripura,Subrata Baidya,Marie A. Onyamboko,Nguyen Hoang Chau,Yok Sovann,Seila Suon,Sokunthea Sreng,Sivanna Mao,Savuth Oun,Sovannary Yen,Chanaki Amaratunga,Chanaki Amaratunga,Chanaki Amaratunga,K Chutasmit,Chalermpon Saelow,Ratchadaporn Runcharern,Weerayuth Kaewmok,Nhu Thi Hoa,Ngo Viet Thanh,Borimas Hanboonkunupakarn,James J. Callery,Akshaya K Mohanty,James Heaton,Myo Thant,Kripasindhu Gantait,Tarapada Ghosh,Roberto Amato,Roberto Amato,Richard D. Pearson,Richard D. Pearson,Christopher G Jacob,Sónia Gonçalves,Mavuto Mukaka,Mavuto Mukaka,Naomi Waithira,Naomi Waithira,Charles J. Woodrow,Charles J. Woodrow,Martin P. Grobusch,Michèle van Vugt,Rick M. Fairhurst,Rick M. Fairhurst,Phaik Yeong Cheah,Phaik Yeong Cheah,Thomas J. Peto,Thomas J. Peto,Lorenz von Seidlein,Lorenz von Seidlein,Mehul Dhorda,Mehul Dhorda,Richard J. Maude,Markus Winterberg,Markus Winterberg,Nguyen Thuy-Nhien,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,Mallika Imwong,Podjanee Jittamala,Khin Lin,Tin Maung Hlaing,Kesinee Chotivanich,Rekol Huy,Caterina I. Fanello,Caterina I. Fanello,Elizabeth A. Ashley,Elizabeth A. Ashley,Elizabeth A. Ashley,Mayfong Mayxay,Mayfong Mayxay,Paul N. Newton,Paul N. Newton,Tran Tinh Hien,Neena Valecha,Frank Smithuis,Sasithon Pukrittayakamee,Sasithon Pukrittayakamee,Abul Faiz,Olivo Miotto,Joel Tarning,Joel Tarning,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White,Arjen M. Dondorp,Arjen M. Dondorp,Nguyen T Thuy-Nhien,Neena Valeche,Nicholas Pj Day +102 more
TL;DR: Triple artemisinin-based combination therapies (TACTs), which combine existing co-formulated ACTs with a second partner drug that is slowly eliminated, might provide effective treatment and delay emergence of antimalarial drug resistance.