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Sebastian Bartschat

Researcher at Leipzig University

Publications -  11
Citations -  665

Sebastian Bartschat is an academic researcher from Leipzig University. The author has contributed to research in topics: Small nucleolar RNA & Genome. The author has an hindex of 9, co-authored 11 publications receiving 592 citations. Previous affiliations of Sebastian Bartschat include Max Planck Society & University of Gothenburg.

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The duck genome and transcriptome provide insight into an avian influenza virus reservoir species

TL;DR: The duck genome sequence and deep transcriptome analyses are presented and it is shown how the duck's defense mechanisms against influenza infection have been optimized through the diversification of its β-defensin and butyrophilin-like repertoires.
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Evolution of the let-7 microRNA Family

TL;DR: This contribution disentangle the evolutionary history of the let-7 locus, which was restructured independently in nematodes, platyhelminths, and deuterostomes and predates the vertebrate-specific genome duplications, which caused a rapid expansion of theLet-7 family.
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PLEXY: Efficient Target Prediction for Box C/D snoRNAs

TL;DR: PLEXY is a dynamic programming algorithm that computes thermodynamically optimal interactions of a box C/D snoRNA with a putative target RNA and is an efficient and reliable tool for the prediction of box C or D snoRNAs target sites.
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U12 type introns were lost at multiple occasions during evolution

TL;DR: The phylogenetic distribution of U2 and U12 introns and spliceosomal RNAs give further support to an early origin of U12 dependent splicing.
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Matching of Soulmates: Coevolution of snoRNAs and Their Targets

TL;DR: It is shown that functions of homologous snoRNAs are evolutionarily stable, thus, members of the same snoRNA family guide equivalent modifications, and the interaction conservation index (ICI) is defined, which serves as an efficient measure to evaluate the conservation of the interaction of sno RNA and target.