W
Wubin Qian
Researcher at Beijing Genomics Institute
Publications - 9
Citations - 6385
Wubin Qian is an academic researcher from Beijing Genomics Institute. The author has contributed to research in topics: Genome & Sequence assembly. The author has an hindex of 7, co-authored 9 publications receiving 5769 citations. Previous affiliations of Wubin Qian include Beijing Institute of Genomics.
Papers
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Journal ArticleDOI
De novo assembly of human genomes with massively parallel short read sequencing
Ruiqiang Li,Hongmei Zhu,Jue Ruan,Wubin Qian,Xiaodong Fang,Zhongbin Shi,Yingrui Li,Shengting Li,Gao Shan,Karsten Kristiansen,Songgang Li,Huanming Yang,Jing Wang,Jun Wang +13 more
TL;DR: The development of this de novo short read assembly method creates new opportunities for building reference sequences and carrying out accurate analyses of unexplored genomes in a cost-effective way.
Journal ArticleDOI
The genome of the cucumber, Cucumis sativus L.
Sanwen Huang,Ruiqiang Li,Zhonghua Zhang,Li Li,Xingfang Gu,Wei Fan,William J. Lucas,Xiaowu Wang,Bingyan Xie,Peixiang Ni,Yuanyuan Ren,Hongmei Zhu,Jun Li,Kui Lin,Weiwei Jin,Zhangjun Fei,Guangcun Li,Jack E. Staub,Andrzej Kilian,Edwin A. G. van der Vossen,Yang Wu,Jie Guo,Jun He,Zhiqi Jia,Yi Ren,Geng Tian,Yao Lu,Jue Ruan,Wubin Qian,Mingwei Wang,Quanfei Huang,Bo Li,Zhaoling Xuan,Jianjun Cao,Asan,Zhigang Wu,Juanbin Zhang,Qingle Cai,Yinqi Bai,Bowen Zhao,Yonghua Han,Ying Li,Xuefeng Li,Shenhao Wang,Qiuxiang Shi,Shiqiang Liu,Won Kyong Cho,Jae-Yean Kim,Yong Xu,Katarzyna Heller-Uszynska,Han Miao,Zhouchao Cheng,Shengping Zhang,Jian Wu,Yuhong Yang,Houxiang Kang,Man Li,Huiqing Liang,Xiaoli Ren,Zhongbin Shi,Ming Wen,Min Jian,Hailong Yang,Guojie Zhang,Zhentao Yang,Rui Chen,Shifang Liu,Jianwen Li,Lijia Ma,Hui Liu,Yan Zhou,Jing Zhao,Xiaodong Fang,Guoqing Li,Lin Fang,Yingrui Li,Dongyuan Liu,Hongkun Zheng,Yong Zhang,Nan Qin,Zhuo Li,Guohua Yang,Shuang Yang,Lars Bolund,Karsten Kristiansen,Hancheng Zheng,Shaochuan Li,Xiuqing Zhang,Huanming Yang,Jing Wang,Rifei Sun,Zhang Baoxi,Shuzhi Jiang,Jun Wang,Yongchen Du,Songgang Li +95 more
TL;DR: This study establishes that five of the cucumber's seven chromosomes arose from fusions of ten ancestral chromosomes after divergence from Cucumis melo, and identifies 686 gene clusters related to phloem function.
Journal ArticleDOI
The sequence and de novo assembly of the giant panda genome
Ruiqiang Li,Wei Fan,Geng Tian,Hongmei Zhu,Lin He,Lin He,Jing Cai,Jing Cai,Quanfei Huang,Qingle Cai,Bo Li,Yinqi Bai,Zhihe Zhang,Ya-Ping Zhang,Wen Wang,Jun Li,Fuwen Wei,Heng Li,Min Jian,Jianwen Li,Zhaolei Zhang,Rasmus Nielsen,Dawei Li,Wanjun Gu,Zhentao Yang,Zhaoling Xuan,Oliver A. Ryder,Frederick C. Leung,Yan Zhou,Jianjun Cao,Xiao Sun,Yonggui Fu,Xiaodong Fang,Xiaosen Guo,Bo Wang,Rong Hou,Fujun Shen,Bo Mu,Peixiang Ni,Runmao Lin,Wubin Qian,Guo-Dong Wang,Guo-Dong Wang,Chang Yu,Wenhui Nie,Jinhuan Wang,Zhigang Wu,Huiqing Liang,Jiumeng Min,Qi Wu,Shifeng Cheng,Jue Ruan,Mingwei Wang,Zhongbin Shi,Ming Wen,Binghang Liu,Xiaoli Ren,Huisong Zheng,Dong Dong,Kathleen Cook,Gao Shan,Hao Zhang,Carolin Kosiol,Xueying Xie,Zuhong Lu,Hancheng Zheng,Yingrui Li,Cynthia C. Steiner,Tommy Tsan-Yuk Lam,Siyuan Lin,Qinghui Zhang,Guoqing Li,Jing Tian,Timing Gong,Hongde Liu,Dejin Zhang,Lin Fang,Chen Ye,Juanbin Zhang,Wenbo Hu,Anlong Xu,Yuanyuan Ren,Guojie Zhang,Guojie Zhang,Michael William Bruford,Qibin Li,Lijia Ma,Yiran Guo,Na An,Yujie Hu,Yang Zheng,Yongyong Shi,Zhiqiang Li,Qing Liu,Yanling Chen,Jing Zhao,Ning Qu,Shancen Zhao,Feng Tian,Xiaoling Wang,Haiyin Wang,Lizhi Xu,Xiao Liu,Tomas Vinar,Yajun Wang,Tak-Wah Lam,Siu-Ming Yiu,Shiping Liu,Hemin Zhang,Desheng Li,Yan Huang,Xia Wang,Guohua Yang,Zhi Jiang,Junyi Wang,Nan Qin,Li Li,Jingxiang Li,Lars Bolund,Karsten Kristiansen,Gane Ka-Shu Wong,Maynard V. Olson,Xiuqing Zhang,Songgang Li,Huanming Yang,Jing Wang,Jun Wang +126 more
TL;DR: Using next-generation sequencing technology alone, a draft sequence of the giant panda genome is generated and assembled, indicating that its bamboo diet might be more dependent on its gut microbiome than its own genetic composition.
Journal ArticleDOI
The yak genome and adaptation to life at high altitude
Qiang Qiu,Guojie Zhang,Tao Ma,Wubin Qian,Junyi Wang,Zhiqiang Ye,Chang-Chang Cao,Quanjun Hu,Jaebum Kim,Jaebum Kim,Denis M. Larkin,Loretta Auvil,Boris Capitanu,Jian Ma,Harris A. Lewin,Xiaoju Qian,Yongshan Lang,Ran Zhou,Lizhong Wang,Kun Wang,Jinquan Xia,Shengguang Liao,Shengkai Pan,Xu Lu,Haolong Hou,Yan Wang,Xuetao Zang,Ye Yin,Hui Ma,Jian Zhang,Zhaofeng Wang,Yingmei Zhang,Dawei Zhang,Takahiro Yonezawa,Masami Hasegawa,Yang Zhong,Wenbin Liu,Yan Zhang,Zhiyong Huang,Shengxiang Zhang,Ruijun Long,Huanming Yang,Jian Wang,Johannes A. Lenstra,David Neil Cooper,Yi Wu,Jun Wang,Jun Wang,Peng Shi,Jianquan Liu,Jianquan Liu +50 more
TL;DR: Positively selected and rapidly evolving genes in the yak lineage are found to be significantly enriched in functional categories and pathways related to hypoxia and nutrition metabolism, which may have important implications for understanding adaptation to high altitude in other animal species and for Hypoxia-related diseases in humans.
Journal ArticleDOI
The duck genome and transcriptome provide insight into an avian influenza virus reservoir species
Yinhua Huang,Yinhua Huang,Yingrui Li,David W. Burt,Hualan Chen,Yong Zhang,Wubin Qian,Heebal Kim,Shangquan Gan,Yiqiang Zhao,Jianwen Li,Kang Yi,Huapeng Feng,Pengyang Zhu,Bo Li,Qiuyue Liu,Susan Fairley,Katharine E. Magor,Zhenlin Du,Xiaoxiang Hu,Laurie Goodman,Hakim Tafer,Hakim Tafer,Alain Vignal,Taeheon Lee,Kyu-Won Kim,Zheya Sheng,Yang An,Steve Searle,Javier Herrero,Martien A. M. Groenen,Richard P. M. A. Crooijmans,Thomas Faraut,Qingle Cai,Robert G. Webster,Jerry R. Aldridge,Wesley C. Warren,Sebastian Bartschat,Stephanie Kehr,Manja Marz,Peter F. Stadler,Peter F. Stadler,Jacqueline Smith,Robert H. S. Kraus,Yaofeng Zhao,Liming Ren,Jing Fei,Mireille Morisson,Peter K. Kaiser,Darren K. Griffin,Man Rao,Frédérique Pitel,Jun Wang,Ning Li +53 more
TL;DR: The duck genome sequence and deep transcriptome analyses are presented and it is shown how the duck's defense mechanisms against influenza infection have been optimized through the diversification of its β-defensin and butyrophilin-like repertoires.