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Sheng-Ce Tao
Researcher at Shanghai Jiao Tong University
Publications - 170
Citations - 5468
Sheng-Ce Tao is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Proteome & Protein microarray. The author has an hindex of 33, co-authored 152 publications receiving 3922 citations. Previous affiliations of Sheng-Ce Tao include Chinese Academy of Sciences & Tsinghua University.
Papers
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Journal ArticleDOI
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir.
Wanchao Yin,Wanchao Yin,Chunyou Mao,Xiaodong Luan,Xiaodong Luan,Dan-Dan Shen,Qingya Shen,Haixia Su,Xiaoxi Wang,Fulai Zhou,Wenfeng Zhao,Minqi Gao,Shenghai Chang,Yuan Chao Xie,Guanghui Tian,He wei Jiang,Sheng-Ce Tao,Jingshan Shen,Yi Jiang,Hualiang Jiang,Yechun Xu,Shuyang Zhang,Yan Zhang,H. Eric Xu +23 more
TL;DR: Cryo–electron microscopy structures of the SARS-CoV-2 RdRp provide insights into the mechanism of viral RNA replication and a rational template for drug design to combat the viral infection.
Journal ArticleDOI
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis.
Yu Yi Lin,Jin-Ying Lu,Junmei Zhang,Wendy Walter,Weiwei Dang,Jun Wan,Sheng-Ce Tao,Jiang Qian,Yingming Zhao,Jef D. Boeke,Shelley L. Berger,Heng Zhu +11 more
TL;DR: A regulatory function for the NuA4 complex in glucose metabolism and life span is demonstrated by acetylating a critical metabolic enzyme.
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SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70.
He wei Jiang,Hai nan Zhang,Qing feng Meng,Jia Xie,Yang Li,Hong Chen,Yun xiao Zheng,Xue ning Wang,Huan Qi,Jing Zhang,Pei-Hui Wang,Ze-Guang Han,Sheng-Ce Tao +12 more
TL;DR: It is reported that Orf9b localizes on the membrane of mitochondria and suppresses type I interferon (IFN-I) responses through association with TOM70, and TOM70 overexpression could largely rescue this inhibition.
Journal ArticleDOI
SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses
He wei Jiang,Yang Li,Hai nan Zhang,Wei Wang,Xiao Yang,Huan Qi,Hua Li,Dong Men,Jie Zhou,Sheng-Ce Tao +9 more
TL;DR: A systemic view of the SARS-CoV-2 specific IgG and IgM responses is presented and provides insights to aid the development of effective diagnostic, therapeutic and vaccination strategies.
Journal ArticleDOI
Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers.
Sheng-Ce Tao,Yu Li,Jiangbing Zhou,Jiang Qian,Ronald L. Schnaar,Ying Zhang,Irwin J. Goldstein,Heng Zhu,Jonathan P. Schneck +8 more
TL;DR: Lectin microarrays are an effective tool for analyzing diverse cell processes including cell development and differentiation, cell-cell communication, pathogen-host recognition, and cell surface biomarker identification.