S
Shinae Kizaka-Kondoh
Researcher at Tokyo Institute of Technology
Publications - 110
Citations - 4936
Shinae Kizaka-Kondoh is an academic researcher from Tokyo Institute of Technology. The author has contributed to research in topics: Tumor hypoxia & Gene. The author has an hindex of 36, co-authored 102 publications receiving 4399 citations. Previous affiliations of Shinae Kizaka-Kondoh include Kyoto University.
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Journal ArticleDOI
Constitutive association of EGF receptor with the CrkII-23 mutant that inhibits transformation of NRK cells by EGF and TGF-β
Satoshi Ota,Shinae Kizaka-Kondoh,Yuko Hashimoto,Hiroshi Nishihara,Kazuo Nagashima,Takeshi Kurata,Hiroto Okayama,Michiyuki Matsuda +7 more
TL;DR: It is suggested that persistent signalling from CrkII-23 bound to EGFR suppresses transformation by EGF and TGF-beta in NRK23 cells.
Journal ArticleDOI
Development of an Oxygen-Sensitive Degradable Peptide Probe for the Imaging of Hypoxia-Inducible Factor-1-Active Regions in Tumors
TL;DR: 123I-DKOP30 is a useful peptide probe for the imaging of HIF-1-active tumors that underwent degradation in a proteasome-dependent manner, while 125I-mDKOP was not degraded.
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Domain architecture of vasohibins required for their chaperone-dependent unconventional extracellular release
Tetsuya Kadonosono,Wanaporn Yimchuen,Takuya Tsubaki,Tadashi Shiozawa,Yasuhiro Suzuki,Takahiro Kuchimaru,Yasufumi Sato,Shinae Kizaka-Kondoh +7 more
TL;DR: A novel UPS regulatory system in which essential domain architecture of VASHs, comprising regions VASH191–180 and VASH280–169, regulate the cytosolic punctate structure formation in the absence of SVBP is identified, which may open up new avenues for understanding fundamental protein secretion in vertebrates.
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In vivo imaging of brain ischemia using an oxygen-dependent degradative fusion protein probe.
Youshi Fujita,Takahiro Kuchimaru,Tetsuya Kadonosono,Shotaro Tanaka,Yoshiki Hase,Hidekazu Tomimoto,Masahiro Hiraoka,Shinae Kizaka-Kondoh,Masafumi Ihara,Ryosuke Takahashi +9 more
TL;DR: In vivo imaging of HIF-active regions using POH-N in ischemic brains after transient focal cerebral ischemia induced using the intraluminal middle cerebral artery occlusion technique in mice is conducted and its potential in imaging and drug delivery is suggested.
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Evaluation of [125I]IPOS as a molecular imaging probe for hypoxia-inducible factor-1-active regions in a tumor: Comparison among single-photon emission computed tomography/X-ray computed tomography imaging, autoradiography, and immunohistochemistry
Masashi Ueda,Takashi Kudo,Yasuko Mutou,Izumi O. Umeda,Azusa Miyano,Kei Ogawa,Masahiro Ono,Hirofumi Fujii,Shinae Kizaka-Kondoh,Masahiro Hiraoka,Hideo Saji +10 more
TL;DR: [123/125I]IPOS can serve as a useful probe for the molecular imaging of HIF‐1‐active tumors and show that the accumulation of radioiodinated POS reflects the expression of Hif‐1.