S
Sonja Bendig
Publications - 3
Citations - 58
Sonja Bendig is an academic researcher. The author has contributed to research in topics: Gene & Gene expression. The author has an hindex of 1, co-authored 1 publications receiving 6 citations.
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Journal ArticleDOI
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia.
Lindsey E. Montefiori,Sonja Bendig,Zhaohui Gu,Xiao-Long Chen,Petri Pölönen,Xiaotu Ma,Alex Murison,Andy G.X. Zeng,Laura García-Prat,Kirsten Dickerson,Ilaria Iacobucci,Sherif Abdelhamed,Ryan Hiltenbrand,Paul E. Mead,Cyrus M. Mehr,Beisi Xu,Zhongshan Cheng,Ti-Cheng Chang,Tamara Westover,Jing Ma,Anna Stengel,Shunsuke Kimura,Chunxu Qu,Marcus B. Valentine,Marissa Rashkovan,Selina M. Luger,Mark R. Litzow,Jacob M. Rowe,Monique L. den Boer,Victoria Wang,Jun Yin,Steven M. Kornblau,Stephen P. Hunger,Mignon L. Loh,Ching-Hon Pui,Wenjian Yang,Kristine R. Crews,Kathryn G. Roberts,Jun J. Yang,Mary V. Relling,William E. Evans,Wendy Stock,Elisabeth Paietta,Adolfo A. Ferrando,Jinghui Zhang,Wolfgang Kern,Torsten Haferlach,Gang Wu,John E. Dick,Jeffery M. Klco,Claudia Haferlach,Charles G. Mullighan +51 more
TL;DR: In this paper, the authors describe a distinct subgroup of acute leukemia with expression of myeloid, T lymphoid, and stem cell markers driven by aberrant allele-specific deregulation of BCL11B, a master transcription factor responsible for thymic T-lineage commitment and specification.
Posted ContentDOI
The gene expression classifier ALLCatchR identifies B-precursor ALL subtypes and underlying developmental trajectories across age
Thomas Beder,Björn-Thore Hansen,A. Hartmann,Johannes Zimmermann,Eric Amelunxen,Nadine Wolgast,Wencke Walter,Marketa Zaliova,Željko Antić,Philippe Chouvarine,Lorenz Bartsch,Malwine J. Barz,M. Bultmann,Johanna Horns,Sonja Bendig,Jan Christian Kässens,Christoph Kaleta,Gunnar Cario,Martin Schrappe,Martino Neumann,Nicola Gökbuget,Anke K. Bergmann,Jan Trka,Claudia Haferlach,Monika Brüggemann,Claudia D. Baldus,Lorenz Bastian +26 more
TL;DR: AllCatchR as discussed by the authors is a machine learning-based classifier using RNA-Seq expression data to allocate B-cell precursor acute lymphoblastic leukemia (BCP-ALL) disease subtypes to 21 defined molecular subtypes.
Journal ArticleDOI
A Multi-Cohort Gene Expression Classifier (ALLCatchR) Identifies B-Precursor ALL Subtypes and Their Developmental Trajectories across Age Groups
Thomas Beder,Björn-Thore Hansen,A. Hartmann,Johannes Zimmermann,Eric Amelunxen,Nadine Kraft,Wencke Walter,Marketa Zaliova,Željko Antić,Philippe Chouvarine,Lorenz Bartsch,M. Bultmann,Sonja Bendig,Jan Christian Kässens,Sören Franzenburg,Christoph Kaleta,Andre Franke,Gunnar Cario,Martin Schrappe,Martino Neumann,Nicola Goekbuget,Anke K. Bergmann,Jan Trka,Claudia Haferlach,Monika Brüggemann,Claudia D. Baldus,Lorenz Bastian +26 more
TL;DR: In this article , a gene expression-based classifier, ALLCatchR, was proposed to identify B-cell precursor acute lymphoblastic leukemia (BCP-ALL) subtypes and related clinical and biological phenotypes.