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Sophie Jeanne Cécile Caron
Researcher at University of Utah
Publications - 20
Citations - 2098
Sophie Jeanne Cécile Caron is an academic researcher from University of Utah. The author has contributed to research in topics: Mushroom bodies & Olfactory system. The author has an hindex of 8, co-authored 19 publications receiving 1868 citations. Previous affiliations of Sophie Jeanne Cécile Caron include Harvard University & Columbia University.
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Journal ArticleDOI
A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease
Benoit G. Bruneau,Georges Nemer,Joachim P. Schmitt,Frédéric Charron,Lynda Robitaille,Sophie Jeanne Cécile Caron,David A. Conner,David A. Conner,Manfred Gessler,Mona Nemer,Christine E. Seidman,Christine E. Seidman,Jonathan G. Seidman,Jonathan G. Seidman +13 more
TL;DR: These studies provide one potential explanation for Holt-Oram syndrome conduction system defects, suggest mechanisms for intrafamilial phenotypic variability, and account for related cardiac malformations caused by other transcription factor mutations.
Journal ArticleDOI
Random convergence of olfactory inputs in the Drosophila mushroom body
TL;DR: This work has developed anatomic tracing techniques to identify the glomerular origin of the inputs that converge onto 200 individual Kenyon cells, and shows that each Kenyon cell integrates input from a different and apparently random combination of glomeruli.
Journal ArticleDOI
Members of the miRNA-200 Family Regulate Olfactory Neurogenesis
Philip S. Choi,Lisa Zakhary,Wen-Yee Choi,Sophie Jeanne Cécile Caron,Ezequiel Alvarez-Saavedra,Eric A. Miska,Michael T. McManus,Brian D. Harfe,Antonio J. Giraldez,Antonio J. Giraldez,H. Robert Horvitz,Alexander F. Schier,Alexander F. Schier,Catherine Dulac +13 more
TL;DR: In this paper, it was shown that miRNAs are required for terminal differentiation of olfactory precursors in both mouse and zebrafish, but are dispensable for proper function of mature neurons.
Journal ArticleDOI
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
David A. Prober,Steven Zimmerman,Benjamin R. Myers,Brian M. McDermott,Seok-Hyung Kim,Sophie Jeanne Cécile Caron,Jason Rihel,Lilianna Solnica-Krezel,David Julius,A. J. Hudspeth,Alexander F. Schier +10 more
TL;DR: A role for zebrafish TRPA1 in chemical but not thermal or mechanical sensing is supported, and a high-throughput system to identify genes and small molecules that modulate chemosensation, thermosensation, and mechanosensation is established.
Journal ArticleDOI
Olfactory receptor and circuit evolution promote host specialization.
Thomas O. Auer,Mohammed A. Khallaf,Ana F. Silbering,Giovanna Zappia,Kaitlyn Ellis,Raquel Álvarez-Ocaña,J. Roman Arguello,Bill S. Hansson,Gregory S.X.E. Jefferis,Sophie Jeanne Cécile Caron,Markus Knaden,Richard Benton +11 more
TL;DR: An accumulation of molecular, physiological and anatomical traits that are linked to behavioural divergence between species are revealed, and a model for investigating speciation and the evolution of the nervous system is defined.