Stephen P. Peters

TL;DR: Five distinct clinical phenotypes of asthma have been identified using an unsupervised hierarchical cluster analysis, which supports clinical heterogeneity in asthma and the need for new approaches for the classification of disease severity in asthma.

TL;DR: The proceedings of an American Thoracic Society (ATS)-sponsored workshop are hoped to serve as an aid to begin to define, understand, and manage these refractory patients.

TL;DR: Severe asthma is characterized by abnormal lung function that is responsive to bronchodilators, a history of sinopulmonary infections, persistent symptoms, and increased health care utilization.

TL;DR: The composition of Bronchial airway microbiota is associated with the degree of bronchial hyperresponsiveness among patients with suboptimally controlled asthma, and these findings support the need for further functional studies to examine the potential contribution of members of theAirway microbiota in asthma pathogenesis.

TL;DR: Genotype at the 16th aminoacid residue of the beta2-adrenergic receptor affects the long-term response to albuterol use and Bronchodilator treatments avoiding albutersol may be appropriate for patients with the Arg/Arg genotype.