S
Stephen J. Smith
Researcher at Allen Institute for Brain Science
Publications - 127
Citations - 22271
Stephen J. Smith is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Postsynaptic potential & Synapse. The author has an hindex of 59, co-authored 118 publications receiving 20466 citations. Previous affiliations of Stephen J. Smith include Stanford University & Yale University.
Papers
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Posted ContentDOI
A solution to temporal credit assignment using cell-type-specific modulatory signals
TL;DR: This work re-analyzes the mathematical basis of gradient descent learning in recurrent spiking neural networks (RSNNs) in light of the recent single-cell transcriptomic evidence for cell-type-specific local neuropeptide signaling in the cortex and suggests a computationally efficient on-chip learning method for bio-inspired artificial intelligence.
Journal ArticleDOI
Array tomography: imaging stained arrays
TL;DR: In this protocol, tissue arrays are imaged using conventional wide-field fluorescence microscopy, which makes it possible to visualize and quantify previously inaccessible features of tissue structure and molecular architecture.
Proceedings ArticleDOI
Integrated Semiconductor Optical Sensors for Chronic, Minimally- Invasive Imaging of Brain Function
Thomas T. Lee,Ofer Levi,Jianhua Cang,Megumi Kaneko,Michael P. Stryker,Stephen J. Smith,Krishna V. Shenoy,James S. Harris +7 more
TL;DR: It is shown that near-infrared IOS imaging at wavelengths compatible with semiconductor devices can produce physiologically significant images in mice, even through skull.
Proceedings ArticleDOI
High throughput integration of optoelectronics devices for biochip fluorescent detection
TL;DR: In this article, the authors used vertical cavity surface emitting lasers (VCSELs), optical emission filters and PIN photodetectors to realize monolithically integrated, near infrared, fluorescence detection systems.
Peer Review
Line Emission Mapper (LEM): Probing the physics of cosmic ecosystems
Ralph P. Kraft,Maxim Markevitch,Caroline A. Kilbourne,Joseph S. Adams,Hiroki Akamatsu,Mohammadreza Ayromlou,Simon R. Bandler,Douglas A. Bennett,Anil Bhardwaj,Veronica Biffi,Dennis Bodewits,Akos Bogdan,Massimiliano Bonamente,Stefano Borgani,Graziella Branduardi-Raymont,Joel N. Bregman,Joseph N. Burchett,Jenna M. Cann,J. A. Carter,Priyanka Chakraborty,E. M. Churazov,Robert A. Crain,Renata Cumbee,Romeel Davé,Michael J. DiPirro,Klaus Dolag,William B. Doriese,Jeremy J. Drake,William F. Dunn,Megan E. Eckart,Dominique Eckert,Stefano Ettori,William R. Forman,Massimiliano Galeazzi,Amy Gall,Efrain Gatuzz,Natalie Hell,Edmund Hodges-Kluck,Caitriona M. Jackman,Amir Jahromi,Frederick A. Jennings,C. Jones,Philip Kaaret,P. J. Kavanagh,Richard L. Kelley,I. Khabibullin,Changgon Kim,Dimitra Koutroumpa,Orsolya E. Kovacs,Kip D. Kuntz,Cheng-Chieh Lin,Erwin T. Lau,Shiu-Hang Lee,Maurice A. Leutenegger,Carey M. Lisse,Lorenzo Lovisari,Dan McCammon,Sean McEntee,François Mernier,Eric N. Miller,Daisuke Nagai,M. Negro,Dylan Nelson,Jan-Uwe Ness,Paul Nulsen,Anna Ogorzalek,Benjamin D. Oppenheimer,Lidia M. Oskinova,Daniel J. Patnaude,Ryan W. Pfeifle,Annalisa Pillepich,Paul P. Plucinsky,David Pooley,F. Scott Porter,Scott W. Randall,Elena Rasia,J.R Raymond,Mateusz Ruszkowski,Kazuhiro Sakai,Arnab Sarkar,Manami Sasaki,Kosuke Sato,G. Schellenberger,Joop Schaye,Aurora Simionescu,Stephen J. Smith,James F. Steiner,Jonathan Stern,Yuanyuan Su,Ming Sun,Grant R. Tremblay,N. Truong,James H. Tutt,Sylvain Veilleux,Alexey Vikhlinin,S. Vladutescu-Zopp,Mark Vogelsberger,Stephen Walker,Kimberly A. Weaver,Dale Weigt,Jessica K. Werk,Norbert Werner,Scott J. Wolk,Congyao Zhang,William W. Zhang,Irina Zhuravleva,John ZuHone +106 more
TL;DR: The Line Emission Mapper (LEM) as discussed by the authors is an X-ray probe for the 2030s that will answer the outstanding questions of the Universe's structure formation, including stellar and black-hole feedback and flows of baryonic matter into and out of galaxies.