S
Stephen J. Smith
Researcher at Allen Institute for Brain Science
Publications - 127
Citations - 22271
Stephen J. Smith is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Postsynaptic potential & Synapse. The author has an hindex of 59, co-authored 118 publications receiving 20466 citations. Previous affiliations of Stephen J. Smith include Stanford University & Yale University.
Papers
More filters
Journal ArticleDOI
A real-time analysis of growth cone-target cell interactions during the formation of stable contacts between hippocampal neurons in culture.
TL;DR: High magnification, real-time record of stable contact formation in cultured cells from the hippocampal CA1 area in the newborn rat indicates that filopodia are the means used by cells to interact at stages prior to and during contact formation.
Journal ArticleDOI
Stability and plasticity of developing synapses in hippocampal neuronal cultures.
TL;DR: FM 1–43 fluorescence imaging observations provide new information on the stability of developing presynaptic function and suggest that NMDA receptor activation may regulate the Stability of developing synapses.
Journal ArticleDOI
Live optical imaging of nervous system development
TL;DR: Technological background is provided and examples of how new methods, including confocal and two-photon microscopy, GFP-based markers, and functional indicators, are being applied to provide fresh insight into long-standing questions of neural development are presented.
Journal ArticleDOI
Endothelin induces a sustained rise in intracellular calcium in hippocampal astrocytes.
TL;DR: The endothelins, a newly described family of vasoactive peptides, have a profound effect on intracellular calcium levels of cultured rat hippocampal astrocytes that resembles the effect of endothelin (ET) on vascular smooth muscle cells (VSMCs) in many respects.
Journal ArticleDOI
A community-developed open-source computational ecosystem for big neuro data.
Joshua T. Vogelstein,Eric Perlman,Benjamin Falk,Alex Baden,William Gray Roncal,Vikram Chandrashekhar,Forrest Collman,Sharmishtaa Seshamani,Jesse L. Patsolic,Kunal Lillaney,Michael Kazhdan,Robert C. Hider,Derek Pryor,Jordan Matelsky,Timothy Gion,Priya Manavalan,Brock A. Wester,Mark A. Chevillet,Eric T. Trautman,Khaled Khairy,Eric W. Bridgeford,Dean M. Kleissas,Daniel J. Tward,Ailey K. Crow,Brian Hsueh,Matthew Wright,Michael I. Miller,Stephen J. Smith,R. Jacob Vogelstein,Karl Deisseroth,Randal Burns +30 more
TL;DR: NeuroData has developed a computational ecosystem that enables storage, visualization, and analysis of these data in the cloud, thusfar spanning 20+ publications and 100+ terabytes, making NeuroData the largest and most diverse open repository of brain data.