S
Suleyman Gulsuner
Researcher at University of Washington
Publications - 65
Citations - 3493
Suleyman Gulsuner is an academic researcher from University of Washington. The author has contributed to research in topics: Population & Germline mutation. The author has an hindex of 22, co-authored 59 publications receiving 2646 citations. Previous affiliations of Suleyman Gulsuner include University of Ibadan & University of California, Santa Barbara.
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Journal ArticleDOI
Inherited Mutations in Women With Ovarian Carcinoma
Barbara M. Norquist,Maria I. Harrell,Mark F. Brady,Tom Walsh,Ming K. Lee,Suleyman Gulsuner,Sarah S. Bernards,Silvia Casadei,Qian Yi,Robert A. Burger,John K. Chan,Susan A. Davidson,Robert S. Mannel,Paul DiSilvestro,Heather A. Lankes,Nilsa C. Ramirez,Mary Claire King,Elizabeth M. Swisher,Michael J. Birrer +18 more
TL;DR: To determine the frequency and importance of germline mutations in cancer-associated genes in OC, a study population of 1915 women with OC and available germline DNA was identified and mutations were compared with the National Heart, Lung, and Blood Institute GO Exome Sequencing Project (ESP) and the Exome Aggregation Consortium (ExAC).
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Spatial and Temporal Mapping of De Novo Mutations in Schizophrenia to a Fetal Prefrontal Cortical Network
Suleyman Gulsuner,Tom Walsh,Amanda C. Watts,Ming K. Lee,Anne M. Thornton,Silvia Casadei,Caitlin Rippey,Hashem Shahin,Vishwajit L. Nimgaonkar,Rodney C.P. Go,Robert Savage,Neal R. Swerdlow,Raquel E. Gur,David L. Braff,Mary Claire King,Jon McClellan +15 more
TL;DR: It is suggested that disruptions of fetal prefrontal cortical neurogenesis are critical to the pathophysiology of schizophrenia and the feasibility of integrating genomic and transcriptome analyses to map critical neurodevelopmental processes in time and space in the brain is supported.
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Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy
Michael Y. Zhang,Jane E. Churpek,Sioban Keel,Tom Walsh,Ming K. Lee,Keith R. Loeb,Suleyman Gulsuner,Colin C. Pritchard,Marilyn Sanchez-Bonilla,Jeffrey J. Delrow,Ryan Basom,Melissa Forouhar,Boglarka Gyurkocza,Bradford S Schwartz,Barbara Neistadt,Rafael Márquez,Christopher J. Mariani,Scott A. Coats,Inga Hofmann,R. Coleman Lindsley,David A. Williams,Janis L. Abkowitz,Marshall S. Horwitz,Mary Claire King,Lucy A. Godley,Akiko Shimamura +25 more
TL;DR: Functional studies show that a central role for ETV6 in hematopoiesis and malignant transformation is identified, and the identification of germline predisposition to cytopenias and cancer informs the diagnosis and medical management of at-risk individuals.
Journal ArticleDOI
Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: An NRG Oncology/Gynecologic Oncology Group Study.
Barbara M. Norquist,Mark F. Brady,Maria I. Harrell,Tom Walsh,Ming K. Lee,Suleyman Gulsuner,Sarah S. Bernards,Silvia Casadei,Robert A. Burger,Krishnansu S. Tewari,Floor J. Backes,Robert S. Mannel,Gretchen E. Glaser,Cheryl Bailey,Stephen C. Rubin,John T. Soper,Heather A. Lankes,Nilsa C. Ramirez,Mary Claire King,Michael J. Birrer,Elizabeth M. Swisher +20 more
TL;DR: HRR mutations, including non-BRCA genes, significantly prolong PFS and OS in ovarian carcinoma and should be stratified for in clinical trials.
Journal ArticleDOI
Missense mutation in the ATPase, aminophospholipid transporter protein ATP8A2 is associated with cerebellar atrophy and quadrupedal locomotion.
Onur Emre Onat,Suleyman Gulsuner,Kaya Bilguvar,Ayşe Nazlı Başak,Haluk Topaloglu,Meliha Tan,Üner Tan,Murat Gunel,Tayfun Ozcelik +8 more
TL;DR: Interestingly, an unrelated individual has been identified, in whom mental retardation and severe hypotonia is associated with a de novo t(10;13) balanced translocation resulting with the disruption of ATP8A2.