S
Sunita Rehal
Researcher at University College London
Publications - 18
Citations - 1510
Sunita Rehal is an academic researcher from University College London. The author has contributed to research in topics: Randomized controlled trial & Malignant pleural effusion. The author has an hindex of 10, co-authored 16 publications receiving 1145 citations.
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Journal ArticleDOI
Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation: A Randomized Clinical Trial
Patrick B. Murphy,Patrick B. Murphy,Sunita Rehal,Gill Arbane,Stephen Bourke,Stephen Bourke,Peter M.A. Calverley,Angela M. Crook,Lee Dowson,Nicholas Duffy,G. John Gibson,Philip D. Hughes,John R. Hurst,Keir Lewis,Rahul Mukherjee,Annabel H. Nickol,Nicholas Oscroft,Maxime Patout,Justin Pepperell,Ian Smith,John Stradling,Jadwiga A. Wedzicha,Michael I. Polkey,Mark Elliott,Nicholas Hart,Nicholas Hart +25 more
TL;DR: Among patients with persistent hypercapnia following an acute exacerbation of COPD, adding home noninvasive ventilation to home oxygen therapy prolonged the time to readmission or death within 12 months.
Journal ArticleDOI
High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial
Martin J. Boeree,Norbert Heinrich,Rob E. Aarnoutse,Andreas H. Diacon,Rodney Dawson,Sunita Rehal,Gibson S. Kibiki,Gavin J. Churchyard,Gavin J. Churchyard,Ian Sanne,Nyanda E. Ntinginya,Lilian T. Minja,Robert D Hunt,Salome Charalambous,Madeleine Hanekom,Hadija H. Semvua,Stellah G. Mpagama,Christina Manyama,Bariki Mtafya,Klaus Reither,Klaus Reither,Robert S. Wallis,Amour Venter,Kim Narunsky,Anka Mekota,Sonja Henne,Angela Colbers,Georgette Plemper van Balen,Stephen H. Gillespie,Patrick P. J. Phillips,Michael Hoelscher +30 more
TL;DR: A dose of 35 mg/kg rifampicin was safe, reduced the time to culture conversion in liquid media, and could be a promising component of future, shorter regimens for the treatment of tuberculosis.
Journal ArticleDOI
A Dose-Ranging Trial to Optimize the Dose of Rifampin in the Treatment of Tuberculosis
Martin J. Boeree,Andreas H. Diacon,Rodney Dawson,Kim Narunsky,J. du Bois,Amour Venter,Patrick P. J. Phillips,Stephen H. Gillespie,Timothy D. McHugh,Michael Hoelscher,Norbert Heinrich,Sunita Rehal,D. van Soolingen,J. van Ingen,C. Magis-Escurra Ibanez,David M. Burger,G. Plemper van Balen,Rob E. Aarnoutse +17 more
TL;DR: There was a nonlinear increase in exposure to rifampin without an apparent ceiling effect and a greater estimated fall in bacterial load in the higher dosing groups, and two weeks of rifampsin up to 35 mg/kg was safe and well tolerated.
Journal ArticleDOI
Effect of opioids vs NSAIDs and larger vs smaller chest tube size on pain control and pleurodesis efficacy among patients with malignant pleural effusion: The TIME1 Randomized Clinical Trial
Najib M. Rahman,Najib M. Rahman,J Pepperell,Sunita Rehal,Tarek Saba,Augustine Tang,Nabeel Ali,Alex West,Gihan Hettiarachchi,Dipak Mukherjee,Johnson Samuel,Andrew Bentley,Lee Dowson,Jonathan Miles,C. Frank Ryan,Ken Y. Yoneda,Anoop Chauhan,John P. Corcoran,Ioannis Psallidas,John M. Wrightson,John M. Wrightson,Robert J. Hallifax,Helen E. Davies,Y. C. Gary Lee,Melissa Dobson,Emma L. Hedley,Douglas Seaton,Nicky Russell,Margaret Chapman,Bethan M. McFadyen,Rachel Shaw,Robert J. O. Davies,Nick A Maskell,Andrew J. Nunn,Robert F. Miller +34 more
TL;DR: Use of NSAIDs vs opiates resulted in no significant difference in pain scores but was associated with more rescue medication, and NSAID use resulted in noninferior rates of pleurodesis efficacy at 3 months.
Journal ArticleDOI
Non-inferiority trials: are they inferior? A systematic review of reporting in major medical journals
TL;DR: Reporting and conduct of non-inferiority trials is inconsistent and does not follow the recommendations in available statistical guidelines, which are not wholly consistent themselves.