S
Suvendra N. Bhattacharyya
Researcher at Indian Institute of Chemical Biology
Publications - 53
Citations - 11403
Suvendra N. Bhattacharyya is an academic researcher from Indian Institute of Chemical Biology. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 22, co-authored 47 publications receiving 10491 citations. Previous affiliations of Suvendra N. Bhattacharyya include Academy of Scientific and Innovative Research & Council of Scientific and Industrial Research.
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Journal ArticleDOI
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
TL;DR: This Review summarizes the current understanding of the mechanistic aspects of microRNA-induced repression of translation and discusses some of the controversies regarding different modes of micro RNA function.
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Inhibition of translational initiation by Let-7 MicroRNA in human cells.
Ramesh S. Pillai,Suvendra N. Bhattacharyya,Caroline G. Artus,Tabea Zoller,Nicolas Cougot,Eugenia Basyuk,Edouard Bertrand,Witold Filipowicz +7 more
TL;DR: It is demonstrated that endogenous let-7 microribonucleoproteins (miRNPs) or the tethering of Argonaute proteins to reporter mRNAs in human cells inhibit translation initiation, suggesting that miRNPs interfere with recognition of the cap.
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Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress
Suvendra N. Bhattacharyya,Regula Habermacher,Ursula Martiné,Ellen I. Closs,Witold Filipowicz +4 more
TL;DR: This work shows that cationic amino acid transporter 1 (CAT-1) mRNA and reporters bearing its 3'UTR can be relieved from the microRNA miR-122-induced inhibition in human hepatocarcinoma cells subjected to different stress conditions and proposes that proteins interacting with the 3'utR will generally act as modifiers altering the potential of miRNAs to repress gene expression.
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Repression of protein synthesis by miRNAs: how many mechanisms?
TL;DR: Mechanistic details of microRNA-mediated repression are starting to emerge but a comprehensive picture of the inhibition, and particularly the effects on mRNA translation, is still lacking.
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Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper
Bogdan Mateescu,Emma J. K. Kowal,Bas W.M. van Balkom,Sabine Bartel,Suvendra N. Bhattacharyya,Edit I. Buzás,Amy H. Buck,Paola de Candia,Franklin Wang Ngai Chow,Saumya Das,Tom A. P. Driedonks,Lola Fernández-Messina,Franziska Haderk,Andrew F. Hill,Jennifer Jones,Kendall Van Keuren-Jensen,Charles P. Lai,Cecilia Lässer,Italia Di Liegro,Taral R. Lunavat,Magdalena J. Lorenowicz,Sybren L. N. Maas,Imre Mäger,María Mittelbrunn,Stefan Momma,Kamalika Mukherjee,Muhammad Nawaz,D. Michiel Pegtel,Michael W. Pfaffl,Raymond M. Schiffelers,Hidetoshi Tahara,Clotilde Théry,Juan Pablo Tosar,Marca H. M. Wauben,Kenneth W. Witwer,Esther N. M. Nolte-‘t Hoen +35 more
TL;DR: This position paper was written by the participants of the workshop to give an overview of the current state of knowledge in the field and to clarify that incomplete knowledge – of the nature of EV(-RNA)s and of how to effectively and reliably study them – currently prohibits the implementation of gold standards in EV-RNA research.