S
Swen Hesse
Researcher at Leipzig University
Publications - 164
Citations - 3971
Swen Hesse is an academic researcher from Leipzig University. The author has contributed to research in topics: Serotonin transporter & Dopaminergic. The author has an hindex of 34, co-authored 151 publications receiving 3367 citations. Previous affiliations of Swen Hesse include Hannover Medical School.
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Journal ArticleDOI
Positron emission tomography with [18F]fluoro‐2‐deoxy‐D‐glucose for diagnosis and staging of bile duct cancer
Regine Kluge,Frank Schmidt,Karel Caca,Henryk Barthel,Swen Hesse,Peter Georgi,Anita Seese,Dominik Huster,Frieder Berr +8 more
TL;DR: PET is highly sensitive and specific for the detection and localization of CC and can be helpful for diagnosis of distant metastases but is not suitable for detection of regional lymph node metastases.
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Serotonin and dopamine transporter imaging in patients with obsessive-compulsive disorder.
Swen Hesse,Ulrich Müller,Ulrich Müller,Thomas Lincke,Henryk Barthel,Thomas Villmann,Matthias C. Angermeyer,Osama Sabri,Katarina Stengler-Wenzke +8 more
TL;DR: Severity of OCD symptoms showed a significant negative correlation with thalamic/hypothalamic SERT availability, and data provide evidence for imbalanced monoaminergic neurotransmitter modulation in OCD.
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Reduced α4β2*–Nicotinic Acetylcholine Receptor Binding and Its Relationship to Mild Cognitive and Depressive Symptoms in Parkinson Disease
Philipp Meyer,Karl Strecker,Kai Kendziorra,Georg Becker,Swen Hesse,Dominique Woelpl,Anke Hensel,Marianne Patt,Dietlind Sorger,Florian Wegner,Donald Lobsien,Henryk Barthel,Peter Brust,Hermann Josef Gertz,Osama Sabri,Johannes Schwarz +15 more
TL;DR: There is a broad reduction of alpha4beta2*-nAChR availability in patients with PD without clinically manifest dementia or depression compared with healthy volunteers, and novel in vivo evidence for a role of the cholinergic neurotransmission in psychiatric comorbidity of PD is provided.
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Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Daniele Mattei,Andranik Ivanov,Carmelo Ferrai,Philipp Jordan,Dilansu Guneykaya,Alice Buonfiglioli,Wandert Schaafsma,Piotr Przanowski,Winnie Deuther-Conrad,Peter Brust,Swen Hesse,Marianne Patt,Osama Sabri,T L Ross,Bart J. L. Eggen,Erik Boddeke,Bozena Kaminska,Dieter Beule,Ana Pombo,Helmut Kettenmann,Susanne A. Wolf +20 more
TL;DR: Using the MIA mouse model, minocycline treatment of adult MIA offspring reverted completely the transcriptional, functional and behavioral deficits, highlighting the potential benefits of therapeutic targeting of microglia in psychiatric disorders.
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99mTechnetium-Ethyl-Cysteinate-Dimer Single-Photon Emission CT Can Predict Fatal Ischemic Brain Edema
Jörg Berrouschot,Henryk Barthel,Rüdiger von Kummer,Wolfram H. Knapp,Swen Hesse,Dietmar Schneider +5 more
TL;DR: Patients with fatal MCA infarction with high accuracy were identified by using 99mTc-ECD SPECT within 6 hours of stroke onset, and this technique offers great potential to select stroke patients for specific therapies, eg, decompressive hemicraniectomy, soon after onset of symptoms.