T
Takeshi Hayashi
Researcher at National Agriculture and Food Research Organization
Publications - 4
Citations - 186
Takeshi Hayashi is an academic researcher from National Agriculture and Food Research Organization. The author has contributed to research in topics: Prepulse inhibition & FABP7. The author has an hindex of 1, co-authored 4 publications receiving 168 citations.
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Journal ArticleDOI
Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype
Akiko Watanabe,Tomoko Toyota,Yuji Owada,Takeshi Hayashi,Yoshimi Iwayama,Miho Matsumata,Yuichi Ishitsuka,Akihiro Nakaya,Motoko Maekawa,Tetsuo Ohnishi,Ryoichi Arai,Katsuyasu Sakurai,Kazuo Yamada,Hisatake Kondo,Kenji Hashimoto,Noriko Osumi,Takeo Yoshikawa +16 more
TL;DR: The results suggest that FABP7 plays a novel and crucial role, linking the NMDA, neurodevelopmental, and glial theories of schizophrenia pathology and the PPI endophenotype, with larger or overt effects in males.
Journal ArticleDOI
Role of an Atypical Cadherin Gene, Cdh23 in Prepulse Inhibition, and Implication of CDH23 in Schizophrenia
Shabeesh Balan,Tetsuo Ohnishi,Akiko Watanabe,Hisako Ohba,Yoshimi Iwayama,Manabu Toyoshima,Tomonori Hara,Yasuko Hisano,Yuki Miyasaka,Yuki Miyasaka,Tomoko Toyota,Chie Shimamoto-Mitsuyama,Motoko Maekawa,Shusuke Numata,Tetsuro Ohmori,Tomomi Shimogori,Yoshiaki Kikkawa,Takeshi Hayashi,Takeo Yoshikawa +18 more
TL;DR: A PPI-regulating Cdh23 variant and a possible contribution of CDH23 to schizophrenia susceptibility are revealed.
Posted ContentDOI
Role of an atypical cadherin gene, Cdh23 in prepulse inhibition and its implication in schizophrenia
Shabeesh Balan,Tetsuo Ohnishi,Akiko Watanabe,Hisako Ohba,Yoshimi Iwayama,Manabu Toyoshima,Tomonori Hara,Yasuko Hisano,Yuki Miyasaka,Tomoko Toyota,Chie Shimamoto-Mitsuyama,Motoko Maekawa,Shusuke Numata,Tetsuro Ohmori,Tomomi Shimogori,Yoshiaki Kikkawa,Takeshi Hayashi,Takeo Yoshikawa +17 more
TL;DR: In this paper, a quantitative trait loci (QTL) for prepulse inhibition (PPI), an endophenotype of schizophrenia, was identified on mouse chromosome 10 and reported Fabp7 as a candidate gene from an analysis of F2 mice from inbred strains with high (C57BL/6N; B6) and low (C3H/HeN; C3H) PPI levels.
Posted ContentDOI
Role of an Atypical Cadherin Gene, Cdh23 in Prepulse Inhibition and Implication of CDH23 in Schizophrenia
Shabeesh Balan,Tetsuo Ohnishi,Akiko Watanabe,Hisako Ohba,Yoshimi Iwayama,Manabu Toyoshima,Tomonori Hara,Yasuko Hisano,Yuki Miyasaka,Tomoko Toyota,Chie Shimamoto-Mitsuyama,Motoko Maekawa,Shusuke Numata,Tetsuro Ohmori,Tomomi Shimogori,Yoshiaki Kikkawa,Takeshi Hayashi,Takeo Yoshikawa +17 more
TL;DR: In this paper, a quantitative trait loci (QTL) for prepulse inhibition (PPI), an endophenotype of schizophrenia, was identified on mouse chromosome 10 and reported Fabp7 as a candidate gene from an analysis of F2 mice from inbred strains with high (C57BL/6N; B6) and low (C3H/HeN; C3H) PPI levels.