T
Tarja Toimela
Researcher at University of Tampere
Publications - 46
Citations - 976
Tarja Toimela is an academic researcher from University of Tampere. The author has contributed to research in topics: Cell culture & Angiogenesis. The author has an hindex of 19, co-authored 42 publications receiving 881 citations. Previous affiliations of Tarja Toimela include National Institute of Chemical Physics and Biophysics.
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The synaptosomal membrane bound ATPase as a target for the neurotoxic effects of pyrethroids, permethrin and cypermethrin
TL;DR: The results support the idea that membrane ATPases are one target of the neurotoxic effect of pyrethroid compounds.
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Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin.
Tarja Toimela,Hanna Tähti +1 more
TL;DR: The study emphasized the toxicity of methylmercury to neural cells and showed that aluminum alters various cellular activities.
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Development of an in vitro blood-brain barrier model-cytotoxicity of mercury and aluminum.
TL;DR: In conclusion, BBB models composed of RBE4 and ARPE-19 cells were able to distinguish between different toxicities, and AR PE- 19 cells are thus promising candidates for studies of drug penetration through the blood-brain barrier.
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Piperonyl butoxide potentiates the synaptosome ATPase inhibiting effect of pyrethrin
TL;DR: The results indicate that PBO is an effective synergist of pyrethrin and that it is very toxic in high concentrations, and confirm that neuronal sodium homeostasis is one target of the neurotoxic effect ofpyrethroid compounds.
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Glutamate Uptake is Inhibited by Tamoxifen and Toremifene in Cultured Retinal Pigment Epithelial Cells
TL;DR: The glutamate uptake was a sensitive target for the effects of tamoxifen and toremifene, and disturbances in this function could be considered as one of the possible mechanisms of retinal defects.