T
Terrell C Roane
Researcher at University of Texas at Austin
Publications - 2
Citations - 155
Terrell C Roane is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Population & Breast cancer. The author has an hindex of 2, co-authored 2 publications receiving 144 citations.
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Journal ArticleDOI
Rare key functional domain missense substitutions in MRE11A , RAD50 , and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study
Francesca Damiola,Maroulio Pertesi,Javier Oliver,Florence Le Calvez-Kelm,Catherine Voegele,Erin L. Young,Nivonirina Robinot,Nathalie Forey,Geoffroy Durand,Maxime Vallée,Kayoko Tao,Terrell C Roane,Gareth J. Williams,John L. Hopper,John L. Hopper,Melissa C. Southey,Irene L. Andrulis,Esther M. John,Esther M. John,David E. Goldgar,Fabienne Lesueur,Fabienne Lesueur,Sean V. Tavtigian +22 more
TL;DR: It is established that MRE11A, RAD50, and NBN are intermediate-risk breast cancer susceptibility genes, and like ATM and CHEK2, their spectrum of pathogenic variants includes a relatively high proportion of missense substitutions.
Journal ArticleDOI
Rare mutations in RINT1 predispose carriers to breast and lynch syndrome-Spectrum cancers
Daniel J. Park,Kayoko Tao,Florence Le Calvez-Kelm,Tu Nguyen-Dumont,Nivonirina Robinot,Fleur Hammet,Fabrice Odefrey,Helen Tsimiklis,Zhi Ling Teo,Louise B. Thingholm,Erin L. Young,Catherine Voegele,Andrew Lonie,Bernard J. Pope,Terrell C Roane,Russell Bell,Hao Hu,Shankaracharya,Chad D. Huff,Jonathan Ellis,Jun Li,Igor V. Makunin,Esther M. John,Esther M. John,Irene L. Andrulis,Mary Beth Terry,Mary B. Daly,Saundra S. Buys,Carrie Snyder,Henry T. Lynch,Peter Devilee,Graham G. Giles,Graham G. Giles,John L. Hopper,John L. Hopper,Bing Jian Feng,Fabienne Lesueur,Fabienne Lesueur,Sean V. Tavtigian,Melissa C. Southey,David E. Goldgar,David E. Goldgar +41 more
TL;DR: RINT1 is added to the growing list of genes in which rare sequence variants are associated with intermediate levels of breast cancer risk, and these findings have clinical applications and raise interesting biological questions.