T
Teun van Gelder
Researcher at Leiden University Medical Center
Publications - 21
Citations - 360
Teun van Gelder is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Dosing & Kidney transplantation. The author has an hindex of 6, co-authored 21 publications receiving 121 citations. Previous affiliations of Teun van Gelder include Erasmus University Medical Center & Leiden University.
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Journal ArticleDOI
Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology
Stein Bergan,Mercè Brunet,Dennis A. Hesselink,Kamisha L. Johnson-Davis,Paweł K. Kunicki,Florian Lemaitre,Pierre Marquet,Mariadelfina Molinaro,Ofelia Noceti,Smita Pattanaik,Tomasz Pawinski,Christoph Seger,Maria Shipkova,Jesse J. Swen,Teun van Gelder,Raman Venkataramanan,Eberhard Wieland,Jean-Baptiste Woillard,Tom C. Zwart,Markus J. Barten,Klemens Budde,Maja Theresa Dieterlen,Laure Elens,Vincent Haufroid,Satohiro Masuda,Olga Millán,Tomoyuki Mizuno,Tomoyuki Mizuno,Dirk Jan A.R. Moes,Michael Oellerich,Nicolas Picard,Linda Salzmann,Burkhard Tönshoff,Ron H.N. van Schaik,Nils Tore Vethe,Alexander A. Vinks,Pierre Wallemacq,Anders Åsberg,Loralie J. Langman +38 more
TL;DR: In this article, the status of personalized treatment with mycophenolic acid (MPA) is discussed, including the criteria for analytics, methods to estimate exposure including pharmacometrics, potential influence of pharmacogenetics, development of biomarkers, and the practical aspects of implementation of target concentration intervention.
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Failure of target attainment of beta-lactam antibiotics in critically ill patients and associated risk factors: a two-center prospective study (EXPAT)
Alan Abdulla,Annemieke Dijkstra,Nicole G. M. Hunfeld,Henrik Endeman,Soma Bahmany,Tim M J Ewoldt,Anouk E. Muller,Teun van Gelder,Diederik Gommers,Birgit C. P. Koch +9 more
TL;DR: Traditional beta-lactam dosing results in low target attainment in the majority of critically ill patients, and male gender, high BMI, and high eGFR were significant risk factors for target non-attainment.
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Severe COVID-19 in a renal transplant recipient: A focus on pharmacokinetics.
Soufian Meziyerh,Tom C. Zwart,Ronald W. van Etten,Jeroen A. Janson,Teun van Gelder,Ian P.J. Alwayn,Johan W. de Fijter,Marlies E.J. Reinders,Dirk Jan A.R. Moes,Aiko P. J. de Vries +9 more
TL;DR: Increased awareness and improved management of drug‐drug interactions associated with the various treatment options for COVID‐19 in renal transplant patients are aimed to achieve.
Journal ArticleDOI
Renal Toxicity From Pemetrexed and Pembrolizumab in the Era of Combination Therapy in Patients With Metastatic Nonsquamous Cell NSCLC
Daphne W. Dumoulin,Sabine Visser,Robin Cornelissen,Teun van Gelder,Johan Vansteenkiste,Jan H. von der Thüsen,Joachim G.J.V. Aerts +6 more
TL;DR: The underlying mechanisms of the renal side effects caused by chemotherapy and ICI therapy are described, leading to a suggested diagnostic and treatment algorithm based on clinical, laboratory, radiographical and pathological parameters that may be a supportive tool for clinicians to diagnose the underlying cause of the acute kidney injury in patients treated with combination chemo- and immunotherapy.
Journal ArticleDOI
Usage of Tacrolimus and Mycophenolic Acid During Conception, Pregnancy, and Lactation, and Its Implications for Therapeutic Drug Monitoring: A Systematic Critical Review
Hoang Lan Le,Marith I. Francke,Louise M. Andrews,Brenda C M de Winter,Teun van Gelder,Dennis A. Hesselink +5 more
TL;DR: Tac treatment during conception, pregnancy, and lactation seems to be safe in terms of the health of the mother, (unborn) child, and allograft, however, Tac may increase the risk of hypertension, preeclampsia, preterm birth, and low birth weight.