T
Theresa Nguyen
Researcher at University of Texas MD Anderson Cancer Center
Publications - 18
Citations - 746
Theresa Nguyen is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Cell culture. The author has an hindex of 10, co-authored 15 publications receiving 644 citations. Previous affiliations of Theresa Nguyen include University of Texas Health Science Center at Houston.
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Journal ArticleDOI
Vimentin is a novel AKT1 target mediating motility and invasion
Quansheng Zhu,Kevin P. Rosenblatt,Kai Lieh Huang,Guy Lahat,Reynolds Brobey,Svetlana Bolshakov,Theresa Nguyen,Zhiyong Ding,Roman Belousov,Kate Lynn J. Bill,Xuemei Luo,Alexander J. Lazar,Adam P. Dicker,Gordon B. Mills,Mien Chie Hung,Mien Chie Hung,Dina Lev +16 more
TL;DR: It is demonstrated that AKT1 activation induces STS cell motility and invasiveness at least partially through a novel interaction with the intermediate filament vimentin (Vim), which was shown to enhance tumor and metastasis growth in vivo.
Journal ArticleDOI
Reirradiation of Head and Neck Cancers With Proton Therapy: Outcomes and Analyses
Jack Phan,Terence T. Sio,Terence T. Sio,Theresa Nguyen,Vinita Takiar,G. Brandon Gunn,Adam S. Garden,David I. Rosenthal,Clifton D. Fuller,William H. Morrison,Beth M. Beadle,Dominic Ma,Mark Zafereo,Katherine A. Hutcheson,Michael E. Kupferman,William N. William,Steven J. Frank +16 more
TL;DR: Proton beam therapy can be a safe and effective curative reirradiation strategy, with acceptable rates of toxicity and durable disease control.
Journal ArticleDOI
Activated MET Is a Molecular Prognosticator and Potential Therapeutic Target for Malignant Peripheral Nerve Sheath Tumors
Keila E. Torres,Quansheng Zhu,Kate Lynn J. Bill,Kate Lynn J. Bill,Gonzalo Lopez,Gonzalo Lopez,Markus P. Ghadimi,Xianbiao Xie,Eric D. Young,Juehui Liu,Theresa Nguyen,Svetlana Bolshakov,Roman Belousov,Suizhau Wang,Guy Lahat,Jun Liu,Belinda F Hernandez,Alexander J. Lazar,Dina Lev,Dina Lev +19 more
TL;DR: An important role is shown for MET in MPNST, supporting continued investigation of novel anti-MET therapies in this clinical context and Informative prognosticators and novel therapies are crucially needed to improve MPN ST management and outcomes.
Journal ArticleDOI
Vascular Endothelial Growth Factor Overexpression by Soft Tissue Sarcoma Cells: Implications for Tumor Growth, Metastasis, and Chemoresistance
Lianglin Zhang,Jonathan A. F. Hannay,Juehui Liu,Parimal Das,Maocheng Zhan,Theresa Nguyen,Daniel J. Hicklin,Dihua Yu,Raphael E. Pollock,Dina Lev +9 more
TL;DR: It is concluded that VEGF is a critical determinant of STS growth and metastasis and that STS chemoresistance, in this model, is a process induced by the interplay between STS cells and tumor-associated endothelial cells.
Journal ArticleDOI
An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors
Tingsheng Peng,Pingyu Zhang,Jeffery Liu,Theresa Nguyen,Svetlana Bolshakov,Roman Belousov,Eric D. Young,Xiaoke Wang,Kari J. Brewer,Delores H López-Terrada,Andre M. Oliveira,Alexander J. Lazar,Dina Lev +12 more
TL;DR: These newly established cellular and xenograft models can facilitate investigation of liposarcomagenesis, dedifferentiation, and tumor progression and may lead to improved therapeutic strategies for patients afflicted by these unfavorable malignancies.