K
Keila E. Torres
Researcher at University of Texas MD Anderson Cancer Center
Publications - 97
Citations - 4331
Keila E. Torres is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Medicine & Sarcoma. The author has an hindex of 27, co-authored 77 publications receiving 3351 citations. Previous affiliations of Keila E. Torres include University of Texas Health Science Center at Houston & University of Puerto Rico.
Papers
More filters
Journal ArticleDOI
Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas
Adam Abeshouse,Clement Adebamowo,Sally N. Adebamowo,Rehan Akbani,Teniola Akeredolu,Adrian Ally,Matthew L. Anderson,Pavana Anur,Elizabeth L. Appelbaum,Joshua Armenia,J. Todd Auman,Matthew A. Bailey,Laurence H. Baker,Miruna Balasundaram,Saianand Balu,Floris P. Barthel,John Bartlett,Stephen B. Baylin,Madhusmita Behera,Dmitry Belyaev,Joesph Bennett,Christopher C. Benz,Rameen Beroukhim,Michael J. Birrer,Therese Bocklage,Tom Bodenheimer,Lori Boice,Moiz S. Bootwalla,Jay Bowen,Reanne Bowlby,Jeff Boyd,Andrew S. Brohl,Denise Brooks,Lauren Averett Byers,Rebecca Carlsen,Patricia Castro,Hsiao-Wei Chen,Andrew D. Cherniack,Frédéric Chibon,Lynda Chin,Juok Cho,Eric Chuah,Sudha Chudamani,Carrie Cibulskis,Lee Cooper,Leslie Cope,Matthew G. Cordes,Daniel Crain,Erin Curley,Ludmila Danilova,Fanny Dao,Ian J. Davis,Lara E. Davis,Timothy Defreitas,Keith A. Delman,John A. Demchok,George D. Demetri,Elizabeth G. Demicco,Noreen Dhalla,Lixia Diao,Li Ding,Phil DiSaia,Peter Dottino,Leona A. Doyle,Esther Drill,Michael Dubina,Jennifer M. Eschbacher,Konstantin V. Fedosenko,Ina Felau,Martin L. Ferguson,Scott Frazer,Catrina Fronick,Victoria Fulidou,Lucinda Fulton,Robert S. Fulton,Stacey Gabriel,Jianjiong Gao,Qingsong Gao,Johanna Gardner,Julie M. Gastier-Foster,Nils Gehlenborg,Mark Gerken,Gad Getz,Andrew K. Godwin,Eryn M. Godwin,Elena Gordienko,Juneko E. Grilley-Olson,David A. Gutman,David H. Gutmann,D. Neil Hayes,Apurva M. Hegde,David I. Heiman,Zachary J. Heins,Carmen Helsel,Austin J. Hepperla,Kelly Higgins,Katherine A. Hoadley,Shital Hobensack,Robert A. Holt,Dave B. Hoon,Jason L. Hornick,Alan P. Hoyle,Xin Hu,Mei Huang,Carolyn M. Hutter,Mary Iacocca,Davis R. Ingram,Michael Ittmann,Lisa Iype,Stuart R. Jefferys,Kevin B. Jones,Corbin D. Jones,Steven J.M. Jones,Tamara Kalir,Beth Y. Karlan,Apollon Karseladze,Katayoon Kasaian,Jaegil Kim,Ritika Kundra,Hanluen Kuo,Marc Ladanyi,Phillip H. Lai,Peter W. Laird,Erik G. Larsson,Michael S. Lawrence,Alexander J. Lazar,Sanghoon Lee,Darlene Lee,Kjong-Van Lehmann,Kristen M. Leraas,Jenny Lester,Douglas A. Levine,Irene Li,Tara M. Lichtenberg,Pei Lin,Jia Liu,Wen-Bin Liu,Eric Minwei Liu,Laxmi Lolla,Yiling Lu,Yussanne Ma,Rashna Madan,Dennis T. Maglinte,Anthony M. Magliocco,Robert G. Maki,David Mallery,Georgy Manikhas,Elaine R. Mardis,Armaz Mariamidze,Marco A. Marra,John A. Martignetti,Cathleen Martinez,Michael Mayo,Michael D. McLellan,Sam Meier,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,Christopher A. Miller,Gordon B. Mills,Richard A. Moore,Scott Morris,Lisle E. Mose,Evgeny Mozgovoy,Andrew J. Mungall,Karen Mungall,Michael Nalisnik,Rashi Naresh,Yulia Newton,Michael S. Noble,Janet E. Novak,Angelica Ochoa,Narciso Olvera,Taofeek K. Owonikoko,Oxana Paklina,Jeremy Parfitt,Joel S. Parker,Alessandro Pastore,Joseph Paulauskis,Robert Penny,Elena Pereira,Charles M. Perou,Amy H. Perou,Todd Pihl,Raphael E. Pollock,Olga Potapova,Amie Radenbaugh,Suresh S. Ramalingam,Nilsa C. Ramirez,W. Kimryn Rathmell,Chandrajit P. Raut,Richard F. Riedel,Colleen Reilly,Sheila Reynolds,Jeffrey Roach,A. Gordon Robertson,Jason Roszik,Brian P. Rubin,Sara Sadeghi,Gordon Saksena,Andrew Salner,Francisco Sanchez-Vega,Chris Sander,Jacqueline E. Schein,Heather Schmidt,Nikolaus Schultz,Steven E. Schumacher,Harman Sekhon,Yasin Senbabaoglu,Galiya Setdikova,Candace Shelton,Troy Shelton,Ronglai Shen,Yan Shi,Juliann Shih,Ilya Shmulevich,Gabriel Sica,Janae V. Simons,Samuel Singer,Payal Sipahimalani,Tara Skelly,Nicholas D. Socci,Heidi J. Sofia,Matthew G. Soloway,Paul T. Spellman,Qiang Sun,Patricia Swanson,Angela Tam,Donghui Tan,Roy Tarnuzzer,Nina Thiessen,Eric M. Thompson,Leigh B. Thorne,Pan Tong,Keila E. Torres,Matt van de Rijn,David Van Den Berg,Brian A. Van Tine,Umadevi Veluvolu,Roel G.W. Verhaak,Doug Voet,Olga Voronina,Yunhu Wan,Zhining Wang,Jing Wang,John N. Weinstein,Daniel J. Weisenberger,Matthew D. Wilkerson,Richard K. Wilson,Lisa Wise,Tina Wong,Wing Hing Wong,John Wrangle,Ye Wu,Matthew A. Wyczalkowski,Liming Yang,Christina Yau,Venkata Yellapantula,Jean C. Zenklusen,Jiashan Zhang,Hailei Zhang,Hongxin Zhang,Erik Zmuda +262 more
TL;DR: This large-scale analysis of 206 adult soft tissue sarcomas reveals previously unappreciated sarcoma-type-specific changes in copy number, methylation, RNA, and protein, providing insights into refining Sarcoma therapy and relationships to other cancer types.
Journal Article
Mechanisms of taxol-induced cell death are concentration dependent
TL;DR: Low concentrations of Taxol induced cell death in the absence of Raf-1 activation, indicating that Taxol-induced cell death is not dependent on Raf- 1 activation, whereas at higher Taxol concentrations (> or = 9 nM) cell death may be the result of a terminal mitotic arrest occurring by a Raf-2-dependent pathway.
Journal ArticleDOI
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Sam Behjati,Sam Behjati,Patrick S. Tarpey,Helen Sheldon,Inigo Martincorena,Peter Van Loo,Peter Van Loo,Gunes Gundem,David C. Wedge,Manasa Ramakrishna,Susanna L. Cooke,Nischalan Pillay,Nischalan Pillay,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Elli Papaemmanuil,Hans Koss,Hans Koss,Tom D. Bunney,Claire Hardy,Olivia Joseph,Sancha Martin,Laura Mudie,Adam Butler,Jon W. Teague,M Patil,Graham Steers,Yu Cao,Curtis Gumbs,Davis R. Ingram,Alexander J. Lazar,Latasha Little,Harshad S. Mahadeshwar,Alexei Protopopov,Ghadah A. Al Sannaa,Sahil Seth,Xingzhi Song,Jiabin Tang,Jianhua Zhang,Vinod Ravi,Keila E. Torres,Bhavisha Khatri,Dina Halai,Ioannis Roxanis,Daniel Baumhoer,Roberto Tirabosco,M Fernanda Amary,Chris Boshoff,Chris Boshoff,Ultan McDermott,Matilda Katan,Michael R. Stratton,P. Andrew Futreal,Adrienne M. Flanagan,Adrienne M. Flanagan,Adrian L. Harris,Adrian L. Harris,Peter J. Campbell,Peter J. Campbell +59 more
TL;DR: This work employed whole-genome, whole-exome and targeted sequencing to study the somatic changes underpinning primary and secondary angiosarcoma, and identified recurrent mutations in two genes, PTPRB and PLCG1, which are intimately linked to angiogenesis.
Journal ArticleDOI
Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies.
Guy Lahat,Quansheng Zhu,Kai Lieh Huang,Suizhao Wang,Svetlana Bolshakov,Jeffery Liu,Keila E. Torres,Robert R. Langley,Alexander J. Lazar,Mien Chie Hung,Dina Lev +10 more
TL;DR: Evaluating Withaferin-A's effects on tumor growth in vitro and in vivo elucidating the role of vimentin in drug-induced responses in soft tissue sarcoma and “epithelial to mesenchymal transition” clinical contexts is warranted.
Journal Article
Elevated Levels of Microtubule Destabilizing Factors in a Taxol-resistant/dependent A549 Cell Line with an α-Tubulin Mutation
Laura A. Martello,Pascal Verdier-Pinard,Heng Jia Shen,Lifeng He,Keila E. Torres,George A. Orr,Susan Band Horwitz +6 more
TL;DR: It is hypothesized that changes in tubulin/MAPs that result in increased microtubule instability may be related to the alpha-tubulin mutation and are compensated for by the stabilizing properties of Taxol.