T
Thomas Martin
Researcher at University of California, San Francisco
Publications - 311
Citations - 17918
Thomas Martin is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Exocytosis. The author has an hindex of 73, co-authored 242 publications receiving 15771 citations. Previous affiliations of Thomas Martin include Institut national de la recherche agronomique & University of Western Australia.
Papers
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Journal ArticleDOI
Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients
Elad Ziv,Eric Dean,Donglei Hu,Alessandro Martino,Daniel J. Serie,Karen Curtin,Daniele Campa,Blake T. Aftab,Paige M. Bracci,Gabriele Buda,Yi Zhao,Jennifer L. Caswell-Jin,Robert B. Diasio,Charles Dumontet,Marek Dudziński,Laura Fejerman,Alexandra J. Greenberg,Scott Huntsman,Krzysztof Jamroziak,Artur Jurczyszyn,Shaji Kumar,Djordje Atanackovic,Martha Glenn,Lisa A. Cannon-Albright,Brandt Jones,Adam M. Lee,Herlander Marques,Thomas Martin,Joaquin Martinez-Lopez,Vincent Rajkumar,Juan Sainz,Annette Juul Vangsted,Marzena Wątek,Jeffrey L. Wolf,Susan L. Slager,Nicola J. Camp,Federico Canzian,Celine M. Vachon +37 more
TL;DR: It is found that the minor allele was associated with increased expression of FOPNL and increased expression is associated with higher expression of centrosomal genes and with shorter survival among MM patients.
Journal ArticleDOI
A dose-finding Phase 2 study of single agent isatuximab (anti-CD38 mAb) in relapsed/refractory multiple myeloma
Joseph R. Mikhael,Joseph R. Mikhael,Joshua R. Richter,Joshua R. Richter,Ravi Vij,Craig E. Cole,Craig E. Cole,Jeffrey A. Zonder,Jonathan L. Kaufman,William I. Bensinger,Meletios A. Dimopoulos,Nikoletta Lendvai,Nikoletta Lendvai,Parameswaran Hari,Enrique M. Ocio,Cristina Gasparetto,Shaji Kumar,Corina Oprea,Marielle Chiron,Claire Brillac,Eric Charpentier,Jesús F. San-Miguel,Thomas Martin +22 more
TL;DR: Isatuximab is active and generally well tolerated in heavily pretreated RRMM, with greatest efficacy at doses ≥10 mg/kg.
Book ChapterDOI
Cell cracking: permeabilizing cells to macromolecular probes.
TL;DR: The ball homogenizer described here can render cells of diameter greater than approximately 10 microns permeable to macromolecular probes, such that the approach may be useful for immunocytochemical studies or for immunoneutralization studies with antibodies directed against antigens involved in a variety of cell functions.
Journal ArticleDOI
SNAP25, but Not Syntaxin 1A, Recycles via an ARF6-regulated Pathway in Neuroendocrine Cells
TL;DR: The results characterize a robust ARF6-dependent internalization mechanism that maintains an intracellular pool of SNAP25, which is compatible with possible intrACEllular roles for SNAP25 in neuroendocrine cells.
Journal ArticleDOI
Munc13 Homology Domain-1 in CAPS/UNC31 Mediates SNARE Binding Required for Priming Vesicle Exocytosis
TL;DR: The results show that MHD1 is a SNARE-binding domain and that SNARE protein binding is essential for CAPS function in dense-core vesicle exocytosis.