Tikva Turetsky

TL;DR: The generation of enriched and expandable preparations of proliferating neural progenitors from human ES cells is reported, indicating that the transplanted cells migrated along established brain migratory tracks in the host brain and differentiated in a region-specific manner, indicating they could respond to local cues and participate in the processes of host brain development.

TL;DR: The International Stem Cell Initiative characterized 59 human embryonic stem cell lines from 17 laboratories worldwide and found that despite diverse genotypes and different techniques used for derivation and maintenance, all lines exhibited similar expression patterns for several markers ofhuman embryonic stem cells.

TL;DR: The presented noggin-dependent controlled conversion of hESC into NPs is valuable for the study of human neurogenesis, the development of new drugs, and is an important step towards the potential utilization of h ESC in neural transplantation therapy.

TL;DR: It is shown that hESC lines can be derived from floating inner cell masses in suspension culture conditions that do not involve feeder cells or microcarriers, paving the way for large-scale expansion and controlled differentiation of hESCs in suspension, which would be valuable in basic and applied research.

TL;DR: This work developed for the first time animal-component free and good manufacturing practice (GMP)-compliant hESCs, derived from umbilical cord tissue and utilized within a novel, xeno-free hESC culture system.