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Tilman B. Drüeke

Researcher at French Institute of Health and Medical Research

Publications -  415
Citations -  22817

Tilman B. Drüeke is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Kidney disease & Hyperparathyroidism. The author has an hindex of 68, co-authored 413 publications receiving 21471 citations. Previous affiliations of Tilman B. Drüeke include Versailles Saint-Quentin-en-Yvelines University & University of Paris-Sud.

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Resistance to Recombinant Human Erythropoietin in Hemodialysis Patients

TL;DR: The administration of recombinant human erythropoietin (rHuEPO) to anemic hemodialysis patients is usually followed by a rapid increase in hemoglobin, and initial 'nonresponders' may either respond to higher doses of rHuEPo or rarely may remain totally unresponsive.
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Factors of increase in serum triglyceride-rich lipoproteins in uremic rats

TL;DR: Evidence is provided against hepatic over-production of TG-rich lipoproteins in rats with chronic renal failure and strongly point to an LPL-mediated defect of their peripheral catabolism, probably related to the insulin deficiency state.
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Uremic toxin indoxyl sulfate inhibits human vascular smooth muscle cell proliferation.

TL;DR: Indoxyl sulfate effects were associated with a dose‐dependent induction of intracellular reactive oxygen species and up‐regulation of p21 and p27 protein expression and inhibition of epidermal growth factor‐induced hVASMC proliferation after long‐term exposure.
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Tissue Accumulation of Lanthanum as Compared to Aluminum in Rats with Chronic Renal Failure – Possible Harmful Effects after Long-Term Exposure

TL;DR: Long-term oral La overload in rats with CRF was associated with a decrease in liver (and total body) weight and mild alterations of liver function, as was Al overload, possibly as a consequence of trace element accumulation.